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Researchers design novel small antibody fragment with improved crystallizability

Antibodies are a powerful weapon system in defending our body against invaders such as bacteria and viruses. Each antibody consists of four polypeptide chains: two heavy chains and two light chains joined to form a Y-shaped molecule.

21 Sep 2017

Study identifies slowly proliferating and highly invasive melanoma cells

A study conducted at The Wistar Institute has led to the identification of a slowly proliferating and highly invasive melanoma cell subpopulation, characterized by production of a protein associated with invasive behavior. The research was published in the journal Oncogene.

21 Sep 2017

Metabolic changes after quitting could help explain how ill-effects of smoking may be reversible

Even after years of smoking, the body has a remarkable ability to repair itself. Now in a study appearing in ACS' Journal of Proteome Research, scientists report that certain metabolic changes occur soon after quitting, and these changes could help explain how some ill-effects of smoking might be reversible.

21 Sep 2017

Study opens new door to potential treatments for highly lethal brain tumors

New research conducted in mice provides evidence that highly lethal brain tumors, called high-grade gliomas, stop growing when deprived of a specific molecule naturally produced when brain cells fire.

21 Sep 2017

UConn Health makes new 3D-printed model of arteries to help surgeons get practice

The first time a young surgeon threads a wire through a stroke victim's chest up through their neck and fishes a blood clot out of their brain may be one of the most harrowing moments in her career.

21 Sep 2017

JAX professor receives $5.4 million grant to study 'cognitive resilience' to Alzheimer's disease

A new five-year grant totaling $5,382,423 to Jackson Laboratory Assistant Professor Catherine Kaczorowski will fund research to explore why some people with a family history of Alzheimer's disease, and even brain changes associated with the disease, nevertheless manage to maintain their cognitive capabilities.

21 Sep 2017

New device can monitor mitochondria in the heart to predict cardiac arrest

A new device can assess in real time whether the body's tissues are receiving enough oxygen and, placed on the heart, can predict cardiac arrest in critically ill heart patients, report researchers at Boston Children's Hospital and scientists from Cambridge device maker Pendar Technologies.

21 Sep 2017

UTMB scientists gain new insights into factors that lead to preterm birth

A group of scientists led by Ramkumar Menon at The University of Texas Medical Branch at Galveston has gained new insights into what factors lead to preterm birth. This study is currently available in The American Journal of Pathology.

21 Sep 2017

MIT engineers design more effective synthetic mRNA delivery system

By delivering strands of genetic material known as messenger RNA into cells, researchers can induce the cells to produce any protein encoded by the mRNA. This technique holds great potential for administering vaccines or treating diseases such as cancer, but achieving efficient delivery of mRNA has proven challenging.

21 Sep 2017

Regeneration ability may lie with the body's innate immune system, study shows

The answer to regenerative medicine's most compelling question -- why some organisms can regenerate major body parts such as hearts and limbs while others, such as humans, cannot -- may lie with the body's innate immune system, according to a new study of heart regeneration in the axolotl, or Mexican salamander, an organism that takes the prize as nature's champion of regeneration.

21 Sep 2017

UCSB scientists receive $9 million NSF funding to develop optical brain-imaging techniques

A multidisciplinary team of researchers, including UC Santa Barbara scientists John Bowers, Michael Goard and Luke Theogarajan, has been awarded $9 million from the National Science Foundation (NSF) to develop and widely share state-of-the-art optical brain-imaging techniques.

21 Sep 2017

Poliovirus therapy triggers longer-lasting immune response against malignant tumors

An investigational therapy using modified poliovirus to attack cancer tumors appears to unleash the body's own capacity to fight malignancies by activating an inflammation process that counter's the ability of cancer cells to evade the immune system.

20 Sep 2017

People with high and low magnesium levels in blood may have increased risk of dementia

People with both high and low levels of magnesium in their blood may have a greater risk of developing dementia, according to a study published in the September 20, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology.

20 Sep 2017

Oxytocin promotes avoidance of unfamiliar situations after negative social interactions

Before you shop for the "cuddle" hormone oxytocin to relieve stress and enhance your social life, read this: a new study from the University of California, Davis, suggests that sometimes, blocking the action of oxytocin in the brain may be a better option.

20 Sep 2017

UTA researcher wins NSF grant to explore new method for accurately analyzing brain image data

Like the organ itself, data collected about the brain is incredibly complex and requires sophisticated methods to sort and analyze. Current methods involve topology, which is a mathematical model that gives a picture of the data, or machine learning, which is a statistical model showing trends. Neither can handle the amounts of data available.

20 Sep 2017

Immune cells may play crucial role in helping the brain heal after hemorrhage or stroke

While immune cells called neutrophils are known to act as infantry in the body's war on germs, a National Institutes of Health-funded study suggests they can act as medics as well. By studying rodents, researchers showed that instead of attacking germs, some neutrophils may help heal the brain after an intracerebral hemorrhage, a form of stroke caused by ruptured blood vessels.

20 Sep 2017

Physical stress in preemies plus separation from mothers may have lasting effects into adulthood

A new study suggests that physiological stress in premature infants combined with separation from their mothers may have lasting effects into adulthood.

20 Sep 2017

Study uncovers millions of previously unknown genes in human microbiome

A new study of the human microbiome- the trillions of microbial organisms that live on and within our bodies- has uncovered millions of previously unknown genes from microbial communities in the human gut, skin, mouth, and vaginal microbiome, allowing for new insights into the role these microbes play in human health and disease.

20 Sep 2017

Penn researchers identify new way to target enzyme crucial to tumor growth, develop new drugs

Opening up a new pathway to fight cancer, researchers at the University of Pennsylvania have found a way to target an enzyme that is crucial to tumor growth while also blocking the mechanism that has made past attempts to target that enzyme resistant to treatment.

20 Sep 2017

Inactivation of Capicua gene leads to formation of T-ALL tumors in mice, researchers find

Researchers at the Spanish National Cancer Research Centre have discovered a genetic alteration that is directly involved in at least 10% of cases of one of the most common cancers in children, T-cell acute lymphoblastic leukemia.

20 Sep 2017

Medical Science News

Researchers design novel small antibody fragment with improved crystallizability

Study identifies slowly proliferating and highly invasive melanoma cells

Metabolic changes after quitting could help explain how ill-effects of smoking may be reversible

Study opens new door to potential treatments for highly lethal brain tumors

UConn Health makes new 3D-printed model of arteries to help surgeons get practice

JAX professor receives $5.4 million grant to study 'cognitive resilience' to Alzheimer's disease

New device can monitor mitochondria in the heart to predict cardiac arrest

UTMB scientists gain new insights into factors that lead to preterm birth

MIT engineers design more effective synthetic mRNA delivery system

Regeneration ability may lie with the body's innate immune system, study shows

UCSB scientists receive $9 million NSF funding to develop optical brain-imaging techniques

Poliovirus therapy triggers longer-lasting immune response against malignant tumors

People with high and low magnesium levels in blood may have increased risk of dementia

Oxytocin promotes avoidance of unfamiliar situations after negative social interactions

UTA researcher wins NSF grant to explore new method for accurately analyzing brain image data

Immune cells may play crucial role in helping the brain heal after hemorrhage or stroke

Physical stress in preemies plus separation from mothers may have lasting effects into adulthood

Study uncovers millions of previously unknown genes in human microbiome

Penn researchers identify new way to target enzyme crucial to tumor growth, develop new drugs

Inactivation of Capicua gene leads to formation of T-ALL tumors in mice, researchers find

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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