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Drug combination produces synergistic effect against growth of triple-negative breast cancer

In the hunt for novel treatments against an aggressive form of breast cancer, researchers combined a new protein inhibitor with a chemotherapy drug to create a powerful combination that resulted in cancer cell death.

26 Sep 2017

MIT study sheds light on flu viruses' rapid evolution

Influenza viruses mutate rapidly, which is why flu vaccines have to be redesigned every year. A new study from MIT sheds light on just how these viruses evolve so quickly and offers a potential way to slow them down.

26 Sep 2017

Study finds no evidence of auditory nerve injury after recreational noise exposure

Exposure to loud noises during common recreational activities is widely cited as a cause of "hidden hearing loss." A new study of young adults, however, finds that while hearing is temporarily affected after attending a loud event, there is no evidence of auditory nerve injury or permanent hearing difficulties.

26 Sep 2017

MIPT scientist proposes unique model to predict cancer development

A scientist from the Moscow Institute of Physics and Technology has proposed a model that can predict the number of key carcinogenic events for each cancer type based on the relationship between morbidity and age.

26 Sep 2017

New approaches to treat aggressive NUT midline carcinoma

Precision medicine, which custom-tailors therapies to the needs of individual patients, is becoming more and more important in cancer therapy. Today, molecular-biological diagnostics can precisely identify alterations in tumor cells.

26 Sep 2017

SBP researcher awarded $10.8 million grant to pursue development of new drug for substance abuse

Sanford Burnham Prebys Medical Discovery Institute is pleased to announce the National Institute on Drug Abuse at the National Institutes of Health has awarded Nicholas Cosford, Ph.D., a three-year, $10.8 million grant to pursue the preclinical development of a new class of medicine to treat substance use disorders.

26 Sep 2017

Researchers identify new mechanism that causes hallmark symptoms of Parkinson's disease

A KAIST research team has identified a new mechanism that causes the hallmark symptoms of Parkinson's disease, namely tremors, rigidity, and loss of voluntary movement.

26 Sep 2017

Lactation hormone also helps establish nurturing link between mother and baby

The same hormone that stimulates milk production for lactation, also acts in the brain to help establish the nurturing link between mother and baby, researchers from New Zealand's University of Otago have revealed for the first time.

26 Sep 2017

Injections of hunger hormone blocker can halt typical weight gain in mice

Mayo Clinic scientists have shown that injections of a hunger hormone blocker in mice can halt the typical weight gain after dieting and help prevent rebound obesity in the long term. The research findings appear in the Proceedings of the National Academy of Sciences.

26 Sep 2017

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Two drugs, already approved for safe use in people, may be able to improve therapy for chronic myeloid leukemia (CML), a blood cancer that affects myeloid cells, according to results from a University of Iowa study in mice.

26 Sep 2017

Researchers use multi-modal integrated approach to develop potential anti-Chagas therapies

Chagas disease is a potentially life-threatening illness caused by the parasite, Trypanosoma cruzi, and is transmitted to humans through triatomine blood-sucking bugs that are commonly referred to as "kissing bugs" or "vampire bugs".

26 Sep 2017

Study: Gene linked to schizophrenia risk controls early neurodevelopment

A gene associated with the risk of schizophrenia regulates critical components of early brain development, according to a new study led by researchers from Penn State University.

26 Sep 2017

New pig model for stroke could accelerate drug discovery process

It is well-known in the medical field that the pig brain shares certain physiological and anatomical similarities with the human brain. So similar are the two that researchers at the University of Georgia's Regenerative Bioscience Center have developed the first U.S. pig model for stroke treatments, which will provide essential preclinical data and speed the drug discovery process.

26 Sep 2017

Breakthrough research offers new insight into function of the brain's anterior cingulate cortex

After four years of lab testing and complex neuro-decoding, a research team led by UNLV psychology professor James Hyman has struck a major breakthrough that could open the floodgates for research into the anterior cingulate cortex, or ACC, and how human brains learn.

26 Sep 2017

Biomaterial-mediated growth factor delivery can restore perfusion of blood vessels in animal models

Ischemia is a serious medical condition in which the flow of blood and delivery of oxygen to tissues is restricted, thus resulting in pain, weakness, and more seriously, tissue and organ damage. Ischemia in muscle tissue, most commonly as a result of atherosclerosis, leads to life-threatening diseases like coronary artery disease and stroke, but also to chronic peripheral artery disease (PAD).

26 Sep 2017

Pediatric researchers discover gene variants related to aggressive form of neuroblastoma

Pediatric researchers investigating the childhood cancer neuroblastoma have identified common gene variants that raise the risk of an aggressive form of that disease. The discovery may assist doctors in better diagnosing subtypes of neuroblastoma.

25 Sep 2017

Drug targeting approach could lead to improved therapies for immune-related diseases

A new technique that targets drugs to specific cells could lead to improved therapies for diseases caused by an overactive immune response.

25 Sep 2017

Treating cartilage grafts with bone marrow concentrate before joint replacement speeds recovery

Biologic joint restoration using donor tissue instead of traditional metal and plastic may be an option for active patients with joint defects. Although recovery from a biologic joint repair is typically longer than traditional replacement, successful biologic restoration allows patients to return to full activity. However, in some cases, the transplanted bone does not heal correctly.

25 Sep 2017

Long-lasting effects of traumatic childhood experiences may be due to impaired neural connections

Researchers from the McGill Group for Suicide Studies, based at the Douglas Mental Health University Institute and McGill University’s Department of Psychiatry, have just published research in the American Journal of Psychiatry that suggests that the long-lasting effects of traumatic childhood experiences, like severe abuse, may be due to an impaired structure and functioning of cells in the anterior cingulate cortex.

25 Sep 2017

Diet plus alcohol may play key role in liver injury development

A new study published in Alcohol and Alcoholism finds that mice bred to consume high amounts of alcohol, but controlled by diet, did not necessarily develop the most severe liver injuries, suggesting that diet may pay an important role in liver injury development.

25 Sep 2017

Medical Science News

Drug combination produces synergistic effect against growth of triple-negative breast cancer

MIT study sheds light on flu viruses' rapid evolution

Study finds no evidence of auditory nerve injury after recreational noise exposure

MIPT scientist proposes unique model to predict cancer development

New approaches to treat aggressive NUT midline carcinoma

SBP researcher awarded $10.8 million grant to pursue development of new drug for substance abuse

Researchers identify new mechanism that causes hallmark symptoms of Parkinson's disease

Lactation hormone also helps establish nurturing link between mother and baby

Injections of hunger hormone blocker can halt typical weight gain in mice

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Researchers use multi-modal integrated approach to develop potential anti-Chagas therapies

Study: Gene linked to schizophrenia risk controls early neurodevelopment

New pig model for stroke could accelerate drug discovery process

Breakthrough research offers new insight into function of the brain's anterior cingulate cortex

Biomaterial-mediated growth factor delivery can restore perfusion of blood vessels in animal models

Pediatric researchers discover gene variants related to aggressive form of neuroblastoma

Drug targeting approach could lead to improved therapies for immune-related diseases

Treating cartilage grafts with bone marrow concentrate before joint replacement speeds recovery

Long-lasting effects of traumatic childhood experiences may be due to impaired neural connections

Diet plus alcohol may play key role in liver injury development

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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