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Pre-clinical study reports promising step forward in search for non-addictive painkillers

A pre-clinical study led by Indiana University scientists reports a promising step forward in the search for pain relief methods without the addictive side effects behind the country's current opioid addiction crisis.

25 Oct 2017

Gut bacteria could hold clues to risk of developing PTSD after traumatic event

The bacteria in your gut could hold clues to whether or not you will develop posttraumatic stress disorder (PTSD) after experiencing a traumatic event.

25 Oct 2017

Pharmacist identifies protein linked to tumor growth in gallbladder cancer

Patients with gallbladder cancer often show few or no symptoms for long periods of time. As a result, the tumors are only detected at a late stage of the disease when treatment is often no longer possible.

25 Oct 2017

Researchers develop new way to genetically engineer T cells for treating leukemia relapse

Researchers at Fred Hutchinson Cancer Research Center and the University of Washington have developed a novel way to genetically engineer T cells that may be effective for treating and preventing leukemia relapse.

25 Oct 2017

Insights from NGLY1 deficiency could provide new approach to treat blood cancers

A new class of drugs for blood cancers such as leukemia and multiple myeloma is showing promise. But it is hobbled by a problem that also plagues other cancer drugs: targeted cells can develop resistance.

25 Oct 2017

Skin plays role in helping regulate blood pressure and heart rate, say scientists

Skin plays a surprising role in helping regulate blood pressure and heart rate, according to scientists at the University of Cambridge and the Karolinska Institute, Sweden. While this discovery was made in mice, the researchers believe it is likely to be true also in humans.

25 Oct 2017

Adopting healthy diet can help reverse risk of high triglycerides, despite genetic predisposition

Triglycerides, a type of fat in the blood, are important for good health. But having high triglycerides might increase a person's risk of heart disease, and may be a sign of metabolic syndrome--a combination of high blood pressure, high blood sugar, and too much fat accumulation at the waist.

25 Oct 2017

Study reveals why Alzheimer's drugs fail in clinical trials

A tremendous amount of Amyloid-β peptide (Aβ) (a peptide of ～40 amino acids) accumulates in the brain of Alzheimer's disease patients. γ-Secretase inhibitors were designed to inhibit the enzymatic activity that produces Aβ. By reducing Aβ production, γ-secretase inhibitors were considered able to treat Alzheimer's disease (Aβ hypothesis).

25 Oct 2017

New discovery could speed development and approval of antiviral drugs

New research shows that a new class of antiviral drugs works by causing the virus' replication machinery to pause and backtrack, preventing the virus from efficiently replicating. This discovery, made possible by a high-throughput experimental technique called "magnetic tweezers," could speed the development and approval of related antiviral drugs.

25 Oct 2017

Research identifies molecular mechanism that causes kidney cancer to resist drug treatment

New research from The University of Texas Health Science Center at San Antonio and U.S. Department of Veterans Affairs has identified the molecular mechanism that causes kidney cancer to resist drug treatment.

25 Oct 2017

Scientists get one step closer to reversing retinal degenerative diseases

Degenerative disorders affecting the retinal pigment epithelium (RPE), such as age-related macular degeneration and autosomal recessive bestrophinopathy, can ultimately lead to blindness. Some of these life-changing disorders are the result of mutations in a single gene, called BEST1.

25 Oct 2017

Researchers mine blood-based epigenetic data to gain insights into autism biology

Using data from blood and brain tissue, a team led by researchers at Johns Hopkins Bloomberg School of Public Health found that they could gain insights into mechanisms that might help explain autism by analyzing the interplay between genes and chemical tags that control whether genes are used to make a protein, called epigenetic marks.

25 Oct 2017

Weight loss following bariatric operation leads to improvements in heart health

In overweight and obese people, fat often gets deposited in the midsection of the body. Large amounts of this belly fat can lead to unhealthy changes in a heart's function and size.

25 Oct 2017

Stony Brook University scientist receives $3.9 million NIH grant for ALS research

Stony Brook University scientist Josh Dubnau, PhD, has received a $3.9 million grant from the National Institutes of Health to investigate the impact of environmental stressors and other external factors that contribute to the development of amyotrophic lateral sclerosis (ALS).

24 Oct 2017

CRISPRy bacon ! Genetically modified leaner low-fat pigs

Genetically modified leaner pigs are on the cards soon. Researchers in china used the gene-editing technology, CRISPR, to create pigs that are less fatty and leaner with more muscle. This could mean genetically modified bacon on the plates.

24 Oct 2017

Myelin sheaths restore impaired nervous system over the long haul

In the central nervous system of humans and all other mammals, a vital insulating sheath composed of lipids and proteins around nerve fibers helps speed the electrical signals or nerve impulses that direct our bodies to walk, talk, breathe, swallow or perform any routine physical act.

24 Oct 2017

NIH launches major effort to discover, catalog the brain's ‘parts list’

The National Institutes of Health has launched a major effort to discover and catalog the brain's "parts list." The NIH's Brain Research through Advancing Innovative Neurotechnologies® Initiative Cell Census Network aims to provide researchers with a comprehensive reference of the diverse cell types in human, monkey, and mouse brain.

24 Oct 2017

APC gene mutations play dual role in development of colorectal cancer, research suggests

Adenomatous polyposis coli (APC) is a gene whose mutations are associated with a rare, hereditary form of colorectal cancer known as familial adenomatous polyposis. Research led by scientists at the Institut Pasteur and Inserm have recently demonstrated that mutations to this gene do not only lead to the emergence of colon polyps; they also harm the immune system, leaving it unable to tackle inflammation of the colonic mucosa.

24 Oct 2017

Study explores role of genes in depression vulnerability

In the current issue of Psychotherapy and Psychosomatics a study explored the role of genes in depression vulnerability. The financial crisis that has afflicted Greece since 2008 has adversely affected the physical and mental health of the population, with reports pointing to a rise in the prevalence of depression from 3.3% prior to the crisis to 12.3% in 2013.

24 Oct 2017

Pollutant from forest and crop fires induces genetic damage in human lung cells

When exposed in a laboratory to pollution levels comparable to those found in the atmosphere of the Amazon region during the forest and crop burning season, human lung cells suffer severe DNA damage and stop dividing. After 72 hours of exposure, over 30% of the cultured cells are dead.

24 Oct 2017

Medical Science News

Pre-clinical study reports promising step forward in search for non-addictive painkillers

Gut bacteria could hold clues to risk of developing PTSD after traumatic event

Pharmacist identifies protein linked to tumor growth in gallbladder cancer

Researchers develop new way to genetically engineer T cells for treating leukemia relapse

Insights from NGLY1 deficiency could provide new approach to treat blood cancers

Skin plays role in helping regulate blood pressure and heart rate, say scientists

Adopting healthy diet can help reverse risk of high triglycerides, despite genetic predisposition

Study reveals why Alzheimer's drugs fail in clinical trials

New discovery could speed development and approval of antiviral drugs

Research identifies molecular mechanism that causes kidney cancer to resist drug treatment

Scientists get one step closer to reversing retinal degenerative diseases

Researchers mine blood-based epigenetic data to gain insights into autism biology

Weight loss following bariatric operation leads to improvements in heart health

Stony Brook University scientist receives $3.9 million NIH grant for ALS research

CRISPRy bacon ! Genetically modified leaner low-fat pigs

Myelin sheaths restore impaired nervous system over the long haul

NIH launches major effort to discover, catalog the brain's ‘parts list’

APC gene mutations play dual role in development of colorectal cancer, research suggests

Study explores role of genes in depression vulnerability

Pollutant from forest and crop fires induces genetic damage in human lung cells

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

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