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Research advance may lead to preservation of hearing in people with Usher syndrome type III

A research advance co-led by Case Western Reserve University School of Medicine's Kumar Alagramam, PhD, may stop the progression of hearing loss and lead to significant preservation of hearing in people with Usher syndrome type III, a form of hereditary hearing loss linked to defects in the sensory "hair" cells in the inner ear. USH3 is caused by a mutation in the clarin-1 gene.

26 Oct 2017

New research may protect Navy divers from oxygen toxicity in the deep

Special Operations divers like Navy SEALs take on life-threatening risks such as enemy combatants and harsh environments. But another hazard is silent and unseen -- oxygen toxicity, the result of breathing lethal levels of oxygen that occur at depth and pressure.

26 Oct 2017

Penn researchers awarded $3.75 million grant to investigate how meal timings affect human health

Disrupting sleep-wake cycles from a predominantly daytime to a delayed eating lifestyle, -- i.e., skipping breakfast and making lunch the first meal of the day, plus eating late dinner, disrupts the body's natural circadian (24-hour) rhythm, the cycle that tells us when to sleep, wake up, eat, and influences hormones and other functions.

26 Oct 2017

Penn study sheds light on genetic cause of early hearing loss

From the moment a baby is born, they are put through a battery of screenings to test for all sorts of characteristics, which includes the sense of hearing.

26 Oct 2017

Scientists define molecular mechanism that triggers pump-induced disease

Researchers at Texas Tech University Health Sciences Center investigated a pump-induced disease and defined the molecular mechanism that triggers it. The study, "On the effect of hyperaldosteronism-inducing mutations in Na/K pumps," was published in the October issue of the Journal of General Physiology.

26 Oct 2017

Dartmouth study uncovers three novel genetic biomarkers for lung cancer

Both environmental and genetic risk factors contribute to development of lung cancer. Tobacco smoking is the most well-known environmental risk factor associated with lung cancer. A Dartmouth research team led by Yafang Li, PhD, has conducted a study to display that gene-smoking interactions play important roles in the etiology of lung cancer.

26 Oct 2017

UC San Diego scientists unravel how ‘resting-state connectivity’ occurs in the brain

Scientists have known that areas of the brain with similar functions--even those in different brain hemispheres--connect to share signals when the body rests, but they haven't known how this "resting-state connectivity" occurs.

26 Oct 2017

Penn study shows how blood flow shapes developing heart valves into mature valve leaflets

Congenital heart valve defects appear in 2 percent of all live births, making them the most common type of birth defect. While some of these defects have been linked to specific genetic mutations, the majority have no clearly definable genetic cause, suggesting that epigenetic factors - changes in gene expression versus an alteration in the genetic code -- play an important role.

26 Oct 2017

New study sheds light on normal function of Parkinson's gene

A new study published in the journal Neuron sheds light on the normal function of LRRK2, the most common genetic cause for late-onset Parkinson's disease. The study was supported by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health.

26 Oct 2017

Wayne State researchers win NIH grant to uncover new antibiotic targets

A research team from Wayne State University has received a $1.85 million grant from the National Institute of General Medical Sciences of the National Institutes of Health for the project "Mechanisms of Non-Shine-Dalgarno Translation Initiation."

26 Oct 2017

Smell sensitivity changes over the course of each day, study suggests

It has always been apparent that some individuals have a better sense of smell than others, but a new study of 37 teens provides the first direct evidence that within each person, smell sensitivity varies over the course of each day. The pattern, according to the data, tracks with the body's internal day-night cycle, or circadian rhythm.

26 Oct 2017

JGU researchers develop new technique to facilitate differentiation of stem cells into neurons

Very little is still known about how neurons can be generated from stem cells. Researchers at the University Medical Center of Johannes Gutenberg University Mainz have now developed a promising technique that will facilitate the differentiation of stem cells into neurons. This even enables them to accelerate the maturation process.

26 Oct 2017

CRISPR - a genetic editor - used to edit DNA and RNA in two parallel studies

Two different studies have shown that CRISPR - a gene editing tool, could be the next big thing in manipulating and modifying the DNA to suit the needs.

26 Oct 2017

Genetic variability of Helicobacter pylori complicates efforts to develop effective vaccine

Helicobacter pylori is a widespread bacterial pathogen that infects the lining of the stomach, where it can cause ulcers and even cancer. As a new study shows, its genetic variability complicates efforts to develop an effective vaccine.

25 Oct 2017

Single infusion of wildtype HSPCs halts cellular damage caused by neuromuscular disorder in mice

Researchers at University of California San Diego School of Medicine report that a single infusion of wildtype hematopoietic stem and progenitor cells (HSPCs) into a mouse model of Friedreich's ataxia (FA) measurably halted cellular damage caused by the degenerative disease.

25 Oct 2017

Higher amounts of physical activity linked to healthier blood biomarkers, study finds

It is well known that being physically active may lower risks of many diseases, such as heart disease and diabetes. In this study, the scientists studied the link between various measures of exercise and eight biomarkers that have previously related to several chronic diseases.

25 Oct 2017

Young hockey players may show post-concussion brain changes even after they return to play

Young hockey players who have suffered concussions may still show changes in the white matter of the brain months after being cleared to return to play, researchers at Western University have found through sophisticated Magnetic Resonance Imaging (MRI) techniques.

25 Oct 2017

Direct application of immune cells accelerates healing of acute, chronic wounds in mice

A Massachusetts General Hospital research team has found a surprising potential solution to a persistent clinical problem - the healing of chronic wounds. In their report published in Wound Repair and Regeneration, the investigators from the MGH Vaccine and Immunotherapy Center describe how application of mature B lymphocytes - the immune cells best known for producing antibodies - greatly accelerated the healing of acute and chronic wounds in both diabetic and nondiabetic mice.

25 Oct 2017

Scientists discover how immune cells clear the way for nerve regeneration after injury

Immune cells are normally associated with fighting infection but in a new study, scientists have discovered how they also help the nervous system clear debris, clearing the way for nerve regeneration after injury.

25 Oct 2017

Researchers find rare genetic variants that may help explain longevity in some CF patients

Cystic fibrosis is an inherited disorder caused by genetic mutations that disrupt the normal movement of chloride in and out of cells. Among other health problems, cystic fibrosis compromises the lungs' ability to fight infection and breathe efficiently, making it the most lethal genetic disease in the Caucasian population. Patients have an average lifespan of just 30 to 40 years.

25 Oct 2017

Medical Science News

Research advance may lead to preservation of hearing in people with Usher syndrome type III

New research may protect Navy divers from oxygen toxicity in the deep

Penn researchers awarded $3.75 million grant to investigate how meal timings affect human health

Penn study sheds light on genetic cause of early hearing loss

Scientists define molecular mechanism that triggers pump-induced disease

Dartmouth study uncovers three novel genetic biomarkers for lung cancer

UC San Diego scientists unravel how ‘resting-state connectivity’ occurs in the brain

Penn study shows how blood flow shapes developing heart valves into mature valve leaflets

New study sheds light on normal function of Parkinson's gene

Wayne State researchers win NIH grant to uncover new antibiotic targets

Smell sensitivity changes over the course of each day, study suggests

JGU researchers develop new technique to facilitate differentiation of stem cells into neurons

CRISPR - a genetic editor - used to edit DNA and RNA in two parallel studies

Genetic variability of Helicobacter pylori complicates efforts to develop effective vaccine

Single infusion of wildtype HSPCs halts cellular damage caused by neuromuscular disorder in mice

Higher amounts of physical activity linked to healthier blood biomarkers, study finds

Young hockey players may show post-concussion brain changes even after they return to play

Direct application of immune cells accelerates healing of acute, chronic wounds in mice

Scientists discover how immune cells clear the way for nerve regeneration after injury

Researchers find rare genetic variants that may help explain longevity in some CF patients

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

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