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Women with low levels of anti-stress hormone at increased risk of getting breast cancer

A new study from Lund University in Sweden shows that women with low levels of an anti-stress hormone have an increased risk of getting breast cancer. The study is the first of its kind on humans and confirms previous similar observations from animal experiments.

15 Jul 2015

Wayne State researcher receives $1.9 million grant to improve EPCs-based cell therapy for vascular diseases

Chunying Li, Ph.D., assistant professor in the Wayne State University School of Medicine's Department of Biochemistry and Molecular Biology, has secured his first R01 grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to study the role and mechanism of the chemokine receptor CXCR2 in regulating new blood vessel formation, the so-called angiogenesis.

15 Jul 2015

New research may explain why youngsters' recovery times vary widely after traumatic brain injury

Why do some youngsters bounce back quickly from a traumatic brain injury, while others suffer devastating side effects for years? New UCLA/USC research suggests that damage to the fatty sheaths around the brain's nerve fibers--not injury severity-- may explain the difference. Published in the July 15 edition of the Journal of Neuroscience, the finding identifies possible biomarkers that physicians could use to predict higher-risk patients who require closer monitoring.

15 Jul 2015

Study highlights how KLF15 protein affects availability of nutrients in the body

Case Western Reserve researchers already demonstrated that a single protein plays a pivotal role in the use of nutrients by major organs that allow for the burning of fat during exercise or regulating the heart's contractile and electrical activity. Now they have found a new benefit of Kruppel-like Factor 15 (KLF15) — keeping the body in metabolic balance.

15 Jul 2015

IU researcher plays role in recent FDA approval of Neupogen drug to treat people exposed to radiation

An Indiana University Melvin and Bren Simon Cancer Center researcher played a role in the recent Food and Drug Administration approval of a drug to treat people exposed to potentially lethal doses of radiation.

15 Jul 2015

Agilent and BTI collaborate to address a critical need in biopharmaceutical industry

The collaboration will address a gap in analytical tests and standards applied for drugs based on glycoproteins, which now form the majority of approved biopharmaceutical drugs. Current analytical methods for characterizing glycans are time-consuming and difficult to deploy in commercial environments. They are also limited in their ability to detect and analyze minor glycan species.

15 Jul 2015

Transplanted MSCs slow progression of lupus nephritis by suppressing Tfh cells in SLE animal model

Systemic lupus erythematosus (SLE) is an autoimmune disease that produces autoantibodies and subsequent immune reactions that can lead to a variety of symptoms, including inflammation of the kidneys, or nephritis. When researchers transplanted mesenchymal stem cells (MSCs) derived from human bone marrow into mice modeled with SLE, they found that inflammation was reduced and nephritis "attenuated."

15 Jul 2015

New study reveals highly promising approach to coating tissue engineered constructs

A new study showing the ability to apply a thin coating of viable respiratory epithelial cells to tissue engineered constructs using a commercially available spray device is especially promising for therapeutic approaches in development to repair or replace challenging structures such as trachea or bronchi.

15 Jul 2015

Study examines how low-methionine diet may help improve outcomes in triple-negative breast cancer patients

A diet that starves triple-negative breast cancer cells of an essential nutrient primes the cancer cells to be more easily killed by a targeted antibody treatment, UW Carbone Cancer Center scientists report in a recent publication.

15 Jul 2015

New study finds that intellectual pursuits can buffer the brain's reward system against drug dependence

Challenging the idea that addiction is hardwired in the brain, a new UC Berkeley study of mice suggests that even a short time spent in a stimulating learning environment can rewire the brain's reward system and buffer it against drug dependence.

15 Jul 2015

Study shows possibility of using embryonic stem cells to repair damaged lung tissue

Collectively, such diseases of the airways as emphysema, bronchitis, asthma and cystic fibrosis are the second leading cause of death worldwide. More than 35 million Americans alone suffer from chronic respiratory disease. Weizmann Institute scientists have now proposed a new direction that could, in the future, lead to the development of a method for alleviating some of their suffering.

15 Jul 2015

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

The Salk Institute today announced that Rusty Gage, Salk professor in the Laboratory of Genetics, has been selected as one of five recipients of the Paul G. Allen Family Foundation's Allen Distinguished Investigator (ADI) program and will be awarded $1.5 million to conduct his research. These researchers have projects aimed at uncovering the elusive biological foundations of Alzheimer's disease.

15 Jul 2015

Imperial Innovations secures EIB loan to support investment in UK biotech, life science sector

Imperial Innovations Group has secured a new GBP 50 million loan from the European Investment Bank to support investment in the UK biotech and life science sector.

14 Jul 2015

New analysis explores importance of medical imaging in drug development, understanding pathological physiology

The use of small animal models in basic and preclinical research is now an integral part of developing and testing new pharmaceutical drugs prior to commercialisation.

14 Jul 2015

Quotient Clinical acquires second GMP manufacturing facility, expands pharmaceutical sciences capabilities

Quotient Clinical, the Translational Pharmaceutics Company, has announced a significant expansion of its pharmaceutical sciences capabilities, doubling capacity through the acquisition of a second GMP manufacturing facility and the construction of new formulation development and pharmaceutical analysis laboratories.

14 Jul 2015

Sleep loss makes memories less accessible during stressful situations

It is known that sleep facilitates the formation of long-term memory in humans. In a new study, researchers from Uppsala University, Sweden, now show that sleep does not only help form long-term memory but also ensures access to it during times of cognitive stress.

14 Jul 2015

Alzheimer's disease may be 'at work' years ahead of actual symptoms, say IU researchers

The best-known genetic variant linked to Alzheimer's disease may be "at work" promoting deposits of plaque in the brain long before any symptoms of the disease can be measured on tests, according to a national research study led by Indiana University School of Medicine investigators.

14 Jul 2015

Scientists gain insights into dynamic remodeling of tissue during lung repair

Our lungs are permanently exposed to harmful environmental factors that can damage or even destroy their cells. In a specific regenerative process these injured cells must be replaced as soon as possible. In collaboration with colleagues from the Max Planck Institute of Biochemistry, scientists at the Helmholtz Zentrum München have now, for the first time, gained detailed insights into the dynamic remodeling of the tissue during lung repair.

14 Jul 2015

Following restrictive sun exposure advice may be harmful to health

Following restrictive sun exposure advice in countries with low solar intensity like Canada might in fact be harmful to your health, says the co-author of a new study on sunlight and vitamin D.

14 Jul 2015

Hiroshima University researchers reveal molecular mechanisms involved in neuropathic pain

A research group from Hiroshima University demonstrated that the downregulation of spinal astrocyte connexin43 (Cx43) expression causes sustained neuropathic pain following peripheral nerve injury. Controlling the Cx43 expression using pharmacological approaches or gene therapy might serve as novel therapeutic strategies ameliorate neurological disorders in general and neuropathic pain in particular.

14 Jul 2015

Medical Science News

Women with low levels of anti-stress hormone at increased risk of getting breast cancer

Wayne State researcher receives $1.9 million grant to improve EPCs-based cell therapy for vascular diseases

New research may explain why youngsters' recovery times vary widely after traumatic brain injury

Study highlights how KLF15 protein affects availability of nutrients in the body

IU researcher plays role in recent FDA approval of Neupogen drug to treat people exposed to radiation

Agilent and BTI collaborate to address a critical need in biopharmaceutical industry

Transplanted MSCs slow progression of lupus nephritis by suppressing Tfh cells in SLE animal model

New study reveals highly promising approach to coating tissue engineered constructs

Study examines how low-methionine diet may help improve outcomes in triple-negative breast cancer patients

New study finds that intellectual pursuits can buffer the brain's reward system against drug dependence

Study shows possibility of using embryonic stem cells to repair damaged lung tissue

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

Imperial Innovations secures EIB loan to support investment in UK biotech, life science sector

New analysis explores importance of medical imaging in drug development, understanding pathological physiology

Quotient Clinical acquires second GMP manufacturing facility, expands pharmaceutical sciences capabilities

Sleep loss makes memories less accessible during stressful situations

Alzheimer's disease may be 'at work' years ahead of actual symptoms, say IU researchers

Scientists gain insights into dynamic remodeling of tissue during lung repair

Following restrictive sun exposure advice may be harmful to health

Hiroshima University researchers reveal molecular mechanisms involved in neuropathic pain

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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