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New approach to treating B-ALL tumour disease

B cell acute lymphoblastic leukaemia, or B-ALL, is the most common tumour disease in children and also occurs in adults. It develops when signalling pathways in immature B cells, or pre-B cells, are dysregulated. Prof. Dr. Markus Müschen from the University of California in San Francisco, USA, and his team worked together with the BIOSS researchers Prof. Dr. Hassan Jumaa and Prof. Dr. Michael Reth to find a new approach for treating the B-ALL tumour disease.

25 Mar 2015

Mesenchymal stem cell transplantation reduces opioid tolerance, opioid-induced pain

Mesenchymal stem cell (MSC) transplantation reduced opioid tolerance and opioid-induced hyperalgesia caused by daily morphine injections in rats, according to new research.

25 Mar 2015

DNA samples collected from tampons may help detect endometrial cancer

Researchers at Mayo Clinic have shown that it is possible to detect endometrial cancer using tumor DNA picked up by ordinary tampons. The new approach specifically examines DNA samples from vaginal secretions for the presence of chemical "off" switches — known as methylation — that can disable genes that normally keep cancer in check.

25 Mar 2015

Biological clue could help explain why some drinkers can't resist alcohol

Virginia Commonwealth University School of Medicine researchers have discovered a biological clue that could help explain why some drinkers develop a dependence on alcohol and others do not.

25 Mar 2015

Brain-somatic-activating mutations in MTOR cause focal cortical dysplasia type II

Epilepsy is a brain disorder that afflicts more than 50 million people worldwide. Many epilepsy patients can control their symptoms through medication, but about 30% suffer from intractable epilepsy and are unable to manage the disease with drugs. Intractable epilepsy causes multiple seizures, permanent mental, physical, and developmental disabilities, and even death.

25 Mar 2015

New research finds link between milk consumption and high levels of glutathione in the brain

New research conducted at the University of Kansas Medical Center has found a correlation between milk consumption and the levels of a naturally-occurring antioxidant called glutathione in the brain in older, healthy adults.

25 Mar 2015

Experimental drug that attacks brain tumor cells passes early tests

An experimental drug that attacks brain tumor tissue by crippling the cells' energy source called the mitochondria has passed early tests in animal models and human tissue cultures, say Houston Methodist scientists.

25 Mar 2015

Mexican researcher close to finding a cure for Parkinson's disease

Parkinson's disease, which took world fame after being diagnosed in various personalities such as actor Michael J. Fox, the heavyweight champion Muhammad Ali and the painter Salvador Dalí, could be very close to a cure, thanks to a Mexican researcher which managed to eliminate its neurological effects with an immunosuppressant.

25 Mar 2015

Study finds clustered cardiometabolic risk factors in children

Lifestyle-related cardiometabolic risk factors cluster already in children in the same way as in adults, according to research from the University of Eastern Finland. A cardiometabolic risk score was used to evaluate cardiometabolic risk in different age groups.

25 Mar 2015

Duke researchers develop new model to study why some HPV infections go away and others progress

For people infected with the human papilloma virus (HPV), the likelihood of clearing the infection and avoiding HPV-related cancer may depend less on the body's disease-fighting arsenal than has been generally assumed.

25 Mar 2015

Testing APOL1 gene variants in deceased kidney donors may improve transplant outcomes

Kidney transplantation outcomes from deceased African-American donors may improve through rapid testing for apolipoprotein L1 gene (APOL1) renal risk variants at the time of organ recovery, according to a new study led by researchers at Wake Forest Baptist Medical Center.

25 Mar 2015

New imaging technique could give precise information about structures inside tissues, cells

One infrared scan can give pathologists a window into the structures and molecules inside tissues and cells, enabling fast and broad diagnostic assessments, thanks to an imaging technique developed by University of Illinois researchers and clinical partners.

25 Mar 2015

Discovery opens door to possible new ways to break transmission cycle of schistosomiasis

Researchers at Oregon State University have discovered a group of genes in one species of snail that provide a natural resistance to the flatworm parasite that causes schistosomiasis, and opens the door to possible new drugs or ways to break the transmission cycle of this debilitating disease.

25 Mar 2015

Broad Institute of MIT researcher honored for groundbreaking research using new gene editing tool

The newest gene editing tool - called CRISPR-Cas9 - is leading to new research possibilities in cell biology and neuroscience. This includes the ability to make transgenic animal models more quickly, which helps researchers better study diseases that affect thousands of people each year.

25 Mar 2015

University of Michigan scientists grow first 3D mini lungs from human stem cells

Scientists from the University of Michigan have grown the first 3D mini lungs from stem cells. The study, published in eLife, compliments other developments in the field such as growing mainly 2D structures and building lung tissue from the scaffold of donated organs.

25 Mar 2015

Funding helps researchers to kiss MS goodbye

Murdoch University researchers have received funding to investigate the link between the Epstein-Barr virus infection, more commonly known as glandular fever or the ‘kissing disease’, and the debilitating disease Multiple Sclerosis (MS).

24 Mar 2015

Non-invasive autopsy service nominated for national award

Sheffield’s radiology team are in the running for a top national medical award after establishing the world’s first minimally invasive autopsy service for babies and children who tragically die in the womb or 28 days after birth.

24 Mar 2015

ISSM selects Elsevier to publish three prestigious journals

Elsevier, a world-leading provider of scientific, technical and medical information products and services, has announced that it has been selected by the International Society for Sexual Medicine (ISSM) to publish its flagship journal, The Journal of Sexual Medicine, as well as Sexual Medicine Reviews and open access journal Sexual Medicine, as of January 2016.

24 Mar 2015

ItpkB enzyme regulates stem cells function to prevent cancer, anemia

Stem cells can generate any type of cell in the body, but they are inactive most of the time--and for good reason. When stem cells become too active and divide too often, they risk acquiring cell damage and mutations.

24 Mar 2015

Exercise and chronic fatigue syndrome: an interview with Professor Trudie Chalder

Chronic fatigue syndrome (CFS) is characterised primarily by fatigue but people often report muscle pain and sleep problems as well as concentration and memory problems. The symptoms affect people’s ability to carry out normal activities that healthy people take for granted. CFS can affect relationships, work and leisure activities.

24 Mar 2015

Medical Science News

New approach to treating B-ALL tumour disease

Mesenchymal stem cell transplantation reduces opioid tolerance, opioid-induced pain

DNA samples collected from tampons may help detect endometrial cancer

Biological clue could help explain why some drinkers can't resist alcohol

Brain-somatic-activating mutations in MTOR cause focal cortical dysplasia type II

New research finds link between milk consumption and high levels of glutathione in the brain

Experimental drug that attacks brain tumor cells passes early tests

Mexican researcher close to finding a cure for Parkinson's disease

Study finds clustered cardiometabolic risk factors in children

Duke researchers develop new model to study why some HPV infections go away and others progress

Testing APOL1 gene variants in deceased kidney donors may improve transplant outcomes

New imaging technique could give precise information about structures inside tissues, cells

Discovery opens door to possible new ways to break transmission cycle of schistosomiasis

Broad Institute of MIT researcher honored for groundbreaking research using new gene editing tool

University of Michigan scientists grow first 3D mini lungs from human stem cells

Funding helps researchers to kiss MS goodbye

Non-invasive autopsy service nominated for national award

ISSM selects Elsevier to publish three prestigious journals

ItpkB enzyme regulates stem cells function to prevent cancer, anemia

Exercise and chronic fatigue syndrome: an interview with Professor Trudie Chalder

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Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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