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New study uncovers how chromosomal changes impact tumor formation and growth

As with most cancers, triple-negative breast cancer (TNBC) cells have abnormal amounts of chromosomes or DNA copy number aberrations (CNAs) in their genomes.

16 Aug 2016

TUM scientists isolate and archive cultured bacterial strains from mouse microbiome

Mouse models are extensively used in pharmaceutical and medical research, and it is known that the communities of microbes in their intestine can have a significant impact on the research output.

12 Aug 2016

St. Jude scientists identify key innate immune sensor that attacks influenza virus

St. Jude Children's Research Hospital immunologists have identified the protein trigger in the body's quick-reaction innate immune system that specifically recognizes the influenza virus in infected cells and triggers their death.

12 Aug 2016

Glia cells may play role in regulating sugar intake into the brain, experts report

Researchers at Technical University of Munich discovered that our brain actively takes sugar from the blood. Prior to this, researchers around the world had assumed that this was a purely passive process.

12 Aug 2016

Intestinal flora likely to have effect on person's response to drugs

Intestinal flora has multiple influences on human health, but researchers have revealed that it is also likely to have an effect on the body's response to drugs.

12 Aug 2016

Former SpaceX engineers launch Synthego, CRISPRevolution to accelerate genome engineering research

Synthego, a leading provider of genome engineering solutions, officially launches today. Synthego’s flagship product line, CRISPRevolution, features synthetic guide RNA products designed to accelerate CRISPR/Cas9 and Cpf1 genome engineering research. CRISPRevolution is the first product line to offer economical access to fully synthetic RNA for high fidelity editing and increased precision in genome editing.

12 Aug 2016

ICR researchers identify how genetic variant linked to leukaemia helps cancer cells survive

Scientists at The Institute of Cancer Research, London, have identified how an inherited genetic variant, associated with an increased risk of developing the most common type of leukaemia, helps cancer cells survive. The findings could lead to new ways to target the disease.

12 Aug 2016

EPFL scientists develop new method to cheaply produce chemical compounds

EPFL scientists design a new method to cheaply produce some of the most important chemical compounds in the pharmaceutical industry - the amines.

12 Aug 2016

FDA grants Orphan Drug Designation to CD4CAR therapy for treatment of peripheral T-cell lymphoma

iCell Gene Therapeutics today (Aug. 11) announced that the Food and Drug Administration has granted Orphan Drug Designation for its chimeric antigen receptor engineered T-cells directed against the target protein CD4 (CD4CAR) for the treatment of peripheral T-cell lymphoma (PTCL).

12 Aug 2016

Specific molecular features control uptake of biguanides into mitochondria to inhibit respiration

The biguanides are a family of drugs with diverse clinical applications. Metformin, a widely used anti-hyperglycemic biguanide, suppresses mitochondrial respiration by inhibiting respiratory complex I. Phenformin, a related anti-hyperglycemic biguanide, also inhibits respiration, but proguanil, which is widely used for the prevention of malaria, does not.

12 Aug 2016

NIH researchers design new set of assays for initial screening of patients with Fragile X syndrome

Fragile X syndrome, the most common heritable cause of intellectual disability and a frequent cause of autism, is characterized by abnormalities of the FMR1 gene that are difficult to analyze.

12 Aug 2016

Scientists discover key molecule that drives regeneration in planarian stem cells

Many living creatures possess exceptional abilities that set them apart from other species. Cheetahs can run up to 60 miles per hour; ants can lift 100 times their body weight; flatworms can regrow amputated body parts.

12 Aug 2016

Food commercials may alter brain mechanisms of children's food choices

Food advertising is a multi-billion dollar industry, with approximately $1.8 billion annually aimed at children and adolescents, who view between 1,000 and 2,000 ads per year.

12 Aug 2016

Study provides detailed picture of genetics underlying type 2 diabetes

The largest study of its kind into type 2 diabetes has produced the most detailed picture to date of the genetics underlying the condition.

12 Aug 2016

Intermediate HDL-C levels linked to lower risk of death

A new study indicates that maintaining an intermediate level of high density lipoprotein cholesterol (HDL-C) may help people live longer.

12 Aug 2016

Long-term brain-machine interface use could lead to recovery in paraplegic patients

During the 2014 FIFA World Cup opening ceremony, a young Brazilian man, paralyzed from the chest down, delivered the opening kickoff. He used a brain-machine interface, allowing him to control the movements of a lower-limb robotic exoskeleton.

12 Aug 2016

Cold plasma could help bones heal faster, study shows

Cold plasma looks like the glow from the "Star Wars" blue light saber but this beam of energy, made of electrons that change polarity at micro-second or nanosecond speeds, could help bones heal faster, according to a study published August 11th in the Journal of Tissue Engineering and Regenerative Medicine.

12 Aug 2016

Scientists find new functions of ANG protein that plays key role in regulation of blood cell formation

Tufts Medical Center and Tufts University scientists have found exciting, new functions of the protein angiogenin that play a significant role in the regulation of blood cell formation, important in bone marrow transplantation and recovery from radiation-induced bone marrow failure.

11 Aug 2016

Scientists identify potential mechanism that paves way for improved treatment of fungal infections

By identifying new compounds that selectively block mitochondrial respiration in pathogenic fungi, Whitehead Institute scientists have identified a potential antifungal mechanism that could enable combination therapy with fluconazole, one of today's most commonly prescribed fungal infection treatments.

11 Aug 2016

Research finding opens new avenues to tailor drug development with Upsalite

For the first time, researchers have revealed the nanostructure of the mesoporous magnesium carbonate Upsalite and pore size control was achieved without organic templates or swelling agents.

11 Aug 2016

Medical Science News

New study uncovers how chromosomal changes impact tumor formation and growth

TUM scientists isolate and archive cultured bacterial strains from mouse microbiome

St. Jude scientists identify key innate immune sensor that attacks influenza virus

Glia cells may play role in regulating sugar intake into the brain, experts report

Intestinal flora likely to have effect on person's response to drugs

Former SpaceX engineers launch Synthego, CRISPRevolution to accelerate genome engineering research

ICR researchers identify how genetic variant linked to leukaemia helps cancer cells survive

EPFL scientists develop new method to cheaply produce chemical compounds

FDA grants Orphan Drug Designation to CD4CAR therapy for treatment of peripheral T-cell lymphoma

Specific molecular features control uptake of biguanides into mitochondria to inhibit respiration

NIH researchers design new set of assays for initial screening of patients with Fragile X syndrome

Scientists discover key molecule that drives regeneration in planarian stem cells

Food commercials may alter brain mechanisms of children's food choices

Study provides detailed picture of genetics underlying type 2 diabetes

Intermediate HDL-C levels linked to lower risk of death

Long-term brain-machine interface use could lead to recovery in paraplegic patients

Cold plasma could help bones heal faster, study shows

Scientists find new functions of ANG protein that plays key role in regulation of blood cell formation

Scientists identify potential mechanism that paves way for improved treatment of fungal infections

Research finding opens new avenues to tailor drug development with Upsalite

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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