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Scientists discover key cellular mechanism behind side-effects of antipsychotics

Since their development in the 1950s, antipsychotic drugs have been widely used to treat psychoses and neuropsychiatric disorders like schizophrenia. A debilitating side-effect of these drugs called parkinsonism limits their efficacy.

7 Jul 2016

Review examines role of gut microbes in development, progression of MS

An increasing number of clinical studies are pointing to a link between the autoimmune disease multiple sclerosis (MS) and the composition of microbes in the human gut, sparking new research on the gut microbiome as a potential target for MS treatment and prevention.

7 Jul 2016

WRAIR collaborates with Sanofi Pasteur to develop ZPIV vaccine candidate

The Walter Reed Army Institute of Research announces a Cooperative Research and Development Agreement for the development of a Zika vaccine candidate with Sanofi Pasteur, the vaccines division of Sanofi.

7 Jul 2016

Genetic test detects colon cancer-linked DNA in blood to predict disease recurrence risk

Scientists at the Johns Hopkins Kimmel Cancer Center and University of Melbourne report they have used a genetic test that spots bits of cancer-related DNA circulating in the blood to accurately predict the likelihood of the disease's return in some — but not all — of a small group of patients with early-stage colon cancer.

7 Jul 2016

AMPK protein activated during fasting regulates hunger neurons in the brain

Neurons in the brain that control hunger are regulated by AMPK, a protein activated during fasting, report researchers from Tufts University School of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School in Neuron on July 6, 2016.

6 Jul 2016

Existing anti-inflammatory drugs may be effective in treating epilepsy

In epileptic patients, seizures lead to an increased level of inflammation-related proteins called chemokines in the brain, and systemic inflammation likely helps trigger and promote the recurrence of seizures, making inflammation a promising new target for anticonvulsant therapy.

6 Jul 2016

Regular marijuana use impacts the brain's natural response to rewards

Most people would get a little 'rush' out of the idea that they're about to win some money.

6 Jul 2016

BU researcher receives grant to better understand breast cancer in African-American women

Why do African-American women die at a higher rate and experience more aggressive breast tumors than white women? Researchers from Boston University's Slone Epidemiology Center (SEC) have received funding from the National Cancer Institute to explore this question.

6 Jul 2016

Changes in benign tissue adjacent to prostate tumors could better predict recurrence

Changes in benign tissues next to prostate tumors may provide an early warning for patients at higher risk for biochemical recurrence after a radical prostatectomy, a study by researchers at Case Western Reserve University and Johns Hopkins Medical Institutions shows.

6 Jul 2016

Phase 1 trial to examine efficacy of promising malaria vaccine in Burkina Faso

Malaria is one of the world's deadliest diseases: it infects hundreds of millions of people every year, and kills about half a million, most of them under five years of age.

6 Jul 2016

Whole-genome omics data can improve accuracy of breast cancer survival predictions

Precise predictions of whether a tumor is likely to spread would help clinicians and patients choose the best course of treatment. But current methods fall short of the precision needed.

6 Jul 2016

Conceptual model highlights transmission of chronic pain risk from parent to children

Can an increased risk of chronic pain be transmitted from parents to children? Several factors may contribute, including genetics, effects on early development, social learning, and more according to a report in the journal PAIN, the official publication of the International Association for the Study of Pain.

6 Jul 2016

Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Maple Syrup Urine Disease (MSUD) is a rare inherited metabolic disorder involving the dysfunction of an enzyme which breaks down three essential amino acids: leucine, isoleucine and valine.

6 Jul 2016

Scientists use Sure Chill technology to develop cost-effective vaccine storage

Vaccines against killer diseases from polio to hepatitis are fragile and can easily be made useless if they get too hot or too cold.

6 Jul 2016

Researchers use FRET to make activation of AMPA receptors optically visible

Our brain is a high-performance computer. One of the key players in this complex system is the AMPA-type glutamate receptor. It ensures that neurotransmission proceeds at a breakneck pace from cell to cell.

6 Jul 2016

Study finds no substantial link between gadolinium exposure and parkinsonism

In a study appearing in the July 5 issue of JAMA, Blayne Welk, M.D., M.Sc., of Western University, London, Canada, and colleagues conducted a study to assess the association between gadolinium exposure and parkinsonism, a degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination.

6 Jul 2016

PREVAIL IV trial opens in Liberia for EVD survivors with persistent traces of Ebola virus RNA

The Partnership for Research on Ebola Virus in Liberia, a U.S.-Liberia joint Clinical Research Partnership, today announced the opening of PREVAIL IV, a treatment trial for men who have survived Ebola virus disease (EVD) but continue to have evidence of Ebola virus genetic material, RNA, in their semen.

6 Jul 2016

Medical Science News

Scientists discover key cellular mechanism behind side-effects of antipsychotics

Review examines role of gut microbes in development, progression of MS

WRAIR collaborates with Sanofi Pasteur to develop ZPIV vaccine candidate

Genetic test detects colon cancer-linked DNA in blood to predict disease recurrence risk

AMPK protein activated during fasting regulates hunger neurons in the brain

Existing anti-inflammatory drugs may be effective in treating epilepsy

Regular marijuana use impacts the brain's natural response to rewards

BU researcher receives grant to better understand breast cancer in African-American women

Changes in benign tissue adjacent to prostate tumors could better predict recurrence

Phase 1 trial to examine efficacy of promising malaria vaccine in Burkina Faso

Whole-genome omics data can improve accuracy of breast cancer survival predictions

Conceptual model highlights transmission of chronic pain risk from parent to children

Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Scientists use Sure Chill technology to develop cost-effective vaccine storage

Researchers use FRET to make activation of AMPA receptors optically visible

Study finds no substantial link between gadolinium exposure and parkinsonism

PREVAIL IV trial opens in Liberia for EVD survivors with persistent traces of Ebola virus RNA

Sleep disturbances, long sleep duration linked to inflammatory illnesses

Scientists discover X-chromosome-inherited type of osteogenesis imperfecta

New lung-targeted gene therapy shows promise in improving treatment for emphysema

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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