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Metal ions released by implant wear can damage progenitors of bone-forming cells

In metal-on-metal pairings, both the shell and head of an implant consist of a cobalt-chromium-molybdenum alloy. The release of metal ions into the body has been reported as a result of implant wear. Bone loss (osteolysis) was observed in many cases.

22 Jun 2016

Hops show promise in reducing breast cancer risk

Hops, the flower cones used in beer-making, are also found in dietary supplements designed to help treat post-menopausal symptoms and other conditions. Scientists are now investigating whether an extract from the plant could also help fend off breast cancer.

22 Jun 2016

Mitofusin 2 protein could serve as therapeutic target to ameliorate sarcopenia in older adults

One of the alterations that most affects the quality of life of the elderly is muscle wastage and the resulting loss of strength, a condition known as sarcopenia. At about 55 years old, people begin to lose muscle mass, this loss continues into old age, at which point it becomes critical.

22 Jun 2016

Study explores anti-Toxoplasma effects of estragole and thymol compounds

The Journal of Parasitology – Many people carry a single-celled parasite known as Toxoplasma gondii but never feel its effects.

22 Jun 2016

Researchers reveal DNA unwrapping can happen asymmetrically to expose specific genes

The protein complex that holds strands of DNA in compact spools partially disassembles itself to help genes reveal themselves to specialized proteins and enzymes for activation, according to Rice University researchers and their colleagues.

22 Jun 2016

Researchers develop plasma QC assay for downstream metabolomics applications

Researchers from IBBL and the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg have investigated the impact of variations in temperature and delays during blood sample processing on downstream metabolomics applications.

22 Jun 2016

New study suggests how rod photoreceptors may have originated to give rise to nocturnal mammals

Retinas from our earliest vertebrate ancestors had cone-like photoreceptors, presumably allowing them to see in daylight, but little ability to see at night. Then, millions of years ago in the Mesozoic era, and in relatively short order, mammals emerged that had retinas with predominantly rod photoreceptors, allowing for them to see at night perhaps to hunt for food while their dinosaur predators were dozing.

22 Jun 2016

Scientists join together to map urban subway microbiome

Scientists at the Centre for Genomic Regulation in Barcelona, Spain, have joined today the Global City Sampling Day for the MetaSub research project. Started in 2013 in New York and led by Dr. Christopher E Mason at Weill Cornell Medicine, MetaSub is an international consortium of laboratories to establish a world-wide "DNA map" of microbiomes in mass transit systems.

22 Jun 2016

Researchers seek to develop novel antibody to treat glioblastoma

Scientists of Helmholtz Zentrum München and the Munich University Hospital are developing a novel antibody to treat brain tumors.

22 Jun 2016

Scientists uncover five new genetic causes of bowel cancer

A landmark study has given the most detailed picture yet of the genetics of bowel cancer - the UK's fourth most common cancer.

22 Jun 2016

Pipeline Embolization Device safe, effective for treatment of complex brain aneurysms

A recently introduced technology called the Pipeline Embolization Device (PED) can provide a less-invasive approach for difficult-to-treat aneurysms of the arteries supplying blood to the front of the brain, reports a study in the July issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, published by Wolters Kluwer.

22 Jun 2016

Scientists detect new genetic candidate for testing treatments that could influence fear learning in PTSD patients

Researchers at The Saban Research Institute of Children's Hospital Los Angeles have identified a new genetic candidate for testing therapies that might affect fear learning in people with PTSD or other conditions. Results of the study have been published in the Journal of Neuroscience.

22 Jun 2016

Moffitt researchers develop mathematical model to show differences in subpopulations of tumors

Tumors are composed of many subpopulations of cells. A general consensus among scientists is that these subpopulations are due to random mutations. However, Moffitt Cancer Center researchers found that these assumptions may be incorrect.

22 Jun 2016

Taking notes can enhance jurors' memory of trial evidence

Jurors who are allowed to take and review notes during court trials are less likely to forget critical evidence, a new University of Liverpool study has found.

22 Jun 2016

First CRISPR/Cas9 screen helps identify human proteins required for Zika virus replication

Scientists at the University of Massachusetts Medical School have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication.

22 Jun 2016

SORLA protein makes fat cells oversensitive to insulin

SORLA is a protein that influences the balance of metabolic processes in adipose tissue, a particular form of fat. Too much of it makes fat cells overly sensitive to insulin, which leads them to break down less fat. SORLA was previously known for its protective role in Alzheimer's disease.

22 Jun 2016

Composition of microbiota plays significant role in body's ability to accept transplanted tissue

Researchers from the University of Chicago have shown that microbiota—the bacteria, viruses and other microbes living on the skin and in the digestive system—play an important role in the body's ability to accept transplanted skin and other organs.

22 Jun 2016

Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

Chronic pain is one of the most prevalent, disabling and expensive public health crises in the United States. It affects more than 100 million Americans, with annual costs estimated at $635 billion, says a 2014 report from the American Pain Society.

22 Jun 2016

New CAR-based therapy using combined cancer target could be effective for solid tumors

Chimeric antigen receptors (CARs), engineered from a patient's own immune cells, have been successful for treating blood cancers, but using CARs for solid tumors has been limited by side effects to normal tissues containing the protein targeted by the engineered cells.

22 Jun 2016

Inflammatory response to mosquito bites can help spread viral infections

Mosquito bite sites are not just itchy, irritating nuisances - they also make viral infections spread by the insects far worse, new research has found.

22 Jun 2016

Medical Science News

Metal ions released by implant wear can damage progenitors of bone-forming cells

Hops show promise in reducing breast cancer risk

Mitofusin 2 protein could serve as therapeutic target to ameliorate sarcopenia in older adults

Study explores anti-Toxoplasma effects of estragole and thymol compounds

Researchers reveal DNA unwrapping can happen asymmetrically to expose specific genes

Researchers develop plasma QC assay for downstream metabolomics applications

New study suggests how rod photoreceptors may have originated to give rise to nocturnal mammals

Scientists join together to map urban subway microbiome

Researchers seek to develop novel antibody to treat glioblastoma

Scientists uncover five new genetic causes of bowel cancer

Pipeline Embolization Device safe, effective for treatment of complex brain aneurysms

Scientists detect new genetic candidate for testing treatments that could influence fear learning in PTSD patients

Moffitt researchers develop mathematical model to show differences in subpopulations of tumors

Taking notes can enhance jurors' memory of trial evidence

First CRISPR/Cas9 screen helps identify human proteins required for Zika virus replication

SORLA protein makes fat cells oversensitive to insulin

Composition of microbiota plays significant role in body's ability to accept transplanted tissue

Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

New CAR-based therapy using combined cancer target could be effective for solid tumors

Inflammatory response to mosquito bites can help spread viral infections

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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