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Certain mosquito species genetically better at transmitting malaria

Certain species of mosquitoes are genetically better at transmitting malaria than even some of their close cousins, according to a multi-institutional team of researchers including Virginia Tech scientists.

28 Nov 2014

Researchers use mathematical models to predict how immune cells respond to disease

Walter and Eliza Hall Institute researchers have defined for the first time how the size of the immune response is controlled, using mathematical models to predict how powerfully immune cells respond to infection and disease.

28 Nov 2014

Study provides proof of concept for developing antibodies against human pathogens

Scientists investigating the potentially deadly hantavirus have used a novel approach to developing protective antibodies against it. Their work, published in today's online edition of Science Translational Medicine, provides proof of concept for producing antibodies against a broad range of human pathogens.

28 Nov 2014

Experimental drug works best when patients' immune cells surrounding tumors express PD-L1

A promising experimental immunotherapy drug works best in patients whose immune defenses initially rally to attack the cancer but then are stymied by a molecular brake that shuts down the response, according to a new study led by researchers at Dana-Farber Cancer Institute and the Yale University School of Medicine.

28 Nov 2014

New study explores how genes interact in relation to the behavior of muscles

How do the genes in the cells inside the body's muscles respond when the muscles are put to work? And how are these genes affected when muscles are not used? What importance do activity and, on the other hand, lack of activity have for the organism's metabolism, and thus also for diseases such as diabetes and obesity? These questions form the basis for a new study from the Department of Public Health at Aarhus University and the Institute of Sports Medicine at Bispebjerg Hospital.

28 Nov 2014

Finding could upend scientific consensus about when embryonic cells begin separating into cell types

Bioengineers at the University of California, San Diego have discovered that mouse embryos are contemplating their cellular fates in the earliest stages after fertilization when the embryo has only two to four cells, a discovery that could upend the scientific consensus about when embryonic cells begin differentiating into cell types.

28 Nov 2014

UCL research opens up new way to treat neurological disorders

The way that tetanus neurotoxin enters nerve cells has been discovered by UCL scientists, who showed that this process can be blocked, offering a potential therapeutic intervention for tetanus. This newly-discovered pathway could be exploited to deliver therapies to the nervous system, opening up a whole new way to treat neurological disorders such as motor neuron disease and peripheral neuropathies.

28 Nov 2014

Researchers discover molecular switch that triggers stress processes in the brain

At the Center for Brain Research at the MedUni Vienna an important factor for stress has been identified in collaboration with the Karolinska Institutet in Stockholm (Sweden). This is the protein secretagogin that plays an important role in the release of the stress hormone CRH and which only then enables stress processes in the brain to be transmitted to the pituitary gland and then onwards to the organs.

28 Nov 2014

Researchers identify key molecule that drives excess protein production in Fragile X patients' brain

People affected by a common inherited form of autism could be helped by a drug that is being tested as a treatment for cancer.

27 Nov 2014

Researchers identify mechanism linked to brain damage

Researchers have discovered a mechanism linked to the brain damage often suffered by stroke victims--and are now searching for drugs to block it.

27 Nov 2014

Astronaut Koichi Wakata carried out live cell experiments with Leica Microsystems’ inverted research microscope

Astronaut Koichi Wakata of the Japan Aerospace Exploration Agency (JAXA) studied the effect of microgravity on bone density as well as on plants building their shape during his stay in the International Space Station (ISS) with an inverted research microscope by Leica Microsystems, the Leica DMI6000 B. He returned to earth with new data from several experiments at the ISS module "Kibo" which will now be evaluated and analyzed by him and collaborating scientists at Japanese research institutions.

From Leica Microsystems GmbH 27 Nov 2014

Uterine contractions have positive effect on artificial insemination

The negative impact of contractions during in vitro fertilisation is a well-known fact. What was unknown until now was the effect it had on artificial insemination.

27 Nov 2014

Extreme Mechanics Letters: New journal from Elsevier

Elsevier, a world-leading provider of scientific, technical and medical information products and solutions, is pleased to announce the launch of a new journal: Extreme Mechanics Letters.

27 Nov 2014

External artificial pancreas improves glucose control, reduces hypoglycemia risk

The world's first clinical trial comparing three alternative treatments for type 1 diabetes was conducted in Montréal by researchers at the IRCM and the University of Montreal, led by endocrinologist Dr. Rémi Rabasa-Lhoret.

27 Nov 2014

GABA injections prevent and reverse Type 1 diabetes in mice

A chemical produced in the pancreas that prevented and even reversed Type 1 diabetes in mice had the same effect on human beta cells transplanted into mice, new research has found.

27 Nov 2014

Researchers investigate role of mitochondria in expansion, survival of cancer stem cells

Cancer stem cells are particularly difficult to eradicate and are at the heart of why it is so hard to more effectively treat cancer patients, as the post-treatment survival of cancer stem cells drives tumour recurrence, the systemic spread of cancer and, ultimately, treatment failure.

From The University of Manchester 27 Nov 2014

Cognitive test battery developed to measure impact of spaceflight stressors on cognitive performance

Space is one of the most demanding and unforgiving environments. Human exploration of space requires astronauts to maintain consistently high levels of cognitive performance to ensure mission safety and success, and prevent potential errors and accidents. Despite the importance of cognitive performance for mission success, little is known about how cognition is affected by prolonged spaceflight, and what aspects of cognition are primarily affected.

27 Nov 2014

Therapeutic nanoparticle safe, effective against H. pylori infection, shows study

The bacterium Helicobacter pylori is strongly associated with gastric ulcers and cancer. To combat the infection, researchers at University of California, San Diego School of Medicine and Jacobs School of Engineering developed LipoLLA, a therapeutic nanoparticle that contains linolenic acid, a component in vegetable oils.

27 Nov 2014

Proper copper levels essential to health of the brain at rest, new study finds

In recent years it has been established that copper plays an essential role in the health of the human brain. Improper copper oxidation has been linked to several neurological disorders including Alzheimer's, Parkinson's, Menkes' and Wilson's.

27 Nov 2014

TET1 enzyme may be important target for cancer diagnostics, treatment

Mutations in the KRAS gene have long been known to cause cancer, and about one third of solid tumors have KRAS mutations or mutations in the KRAS pathway. KRAS promotes cancer formation not only by driving cell growth and division, but also by turning off protective tumor suppressor genes, which normally limit uncontrolled cell growth and cause damaged cells to self-destruct.

27 Nov 2014

Medical Science News

Certain mosquito species genetically better at transmitting malaria

Researchers use mathematical models to predict how immune cells respond to disease

Study provides proof of concept for developing antibodies against human pathogens

Experimental drug works best when patients' immune cells surrounding tumors express PD-L1

New study explores how genes interact in relation to the behavior of muscles

Finding could upend scientific consensus about when embryonic cells begin separating into cell types

UCL research opens up new way to treat neurological disorders

Researchers discover molecular switch that triggers stress processes in the brain

Researchers identify key molecule that drives excess protein production in Fragile X patients' brain

Researchers identify mechanism linked to brain damage

Astronaut Koichi Wakata carried out live cell experiments with Leica Microsystems’ inverted research microscope

Uterine contractions have positive effect on artificial insemination

Extreme Mechanics Letters: New journal from Elsevier

External artificial pancreas improves glucose control, reduces hypoglycemia risk

GABA injections prevent and reverse Type 1 diabetes in mice

Researchers investigate role of mitochondria in expansion, survival of cancer stem cells

Cognitive test battery developed to measure impact of spaceflight stressors on cognitive performance

Therapeutic nanoparticle safe, effective against H. pylori infection, shows study

Proper copper levels essential to health of the brain at rest, new study finds

TET1 enzyme may be important target for cancer diagnostics, treatment

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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