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New technology reveals cellular gene transcription process in detail

A new technology that reveals cellular gene transcription in greater detail has been developed by Dr. Daniel Kaufmann of the University of Montreal Hospital Research Centre and the research team he directed. "This new research tool offers us a more profound view of the immune responses that are involved in a range of diseases, such as HIV infection. At the level of gene transcription, this had been difficult, complex and costly to do with current technologies, such as microscopy," explained the University of Montreal professor.

4 Dec 2014

Controlling neural excitations may help prevent detrimental effects like those in stroke, say scientists

What do lasers, neural networks, and spreading epidemics have in common? They share a most basic feature whereby an initial pulse can propagate through a medium - be it physical, biological or socio-economic, respectively. The challenge is to gain a better understanding - and eventually control - of such systems, allowing them to be applied, for instance to real neural systems. This is the objective of a new theoretical study published in EPJ B by Clemens Bachmair and Eckehard Schöll from the Berlin University of Technology in Germany.

4 Dec 2014

New light-triggered strategy can provide accurate control over aptamer-based therapeutics

While aptamers—single-stranded nucleic acids—offer promise as drug-delivery tools for cancer treatment, it has proven difficult to get them to tumor cells at therapeutic levels.

4 Dec 2014

New chemical compound shows promise in restoring function lost to spinal cord injury

Case Western Reserve scientists have developed a new chemical compound that shows extraordinary promise in restoring function lost to spinal cord injury. The compound, which the researchers dubbed intracellular sigma peptide (ISP), allowed paralyzed muscles to activate in more than 80 percent of the animals tested.

4 Dec 2014

UAB research suggests potential therapeutic target for patients with frontotemporal dementia

Drugs that boost the function of a specific type of neurotransmitter receptor may provide benefit to patients with the second most common type of dementia, according to research by scientists at the University of Alabama at Birmingham published today in the Journal of Neuroscience.

4 Dec 2014

Researchers identify biochemical mechanism that could lead to 'chemo brain'

UNC School of Medicine researchers have found for the first time a biochemical mechanism that could be a cause of "chemo brain" - the neurological side effects such as memory loss, confusion, difficulty thinking, and trouble concentrating that many cancer patients experience while on chemotherapy to treat tumors in other parts of the body.

4 Dec 2014

Scientists review HBV-associated tumor microenvironment in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the few cancers in which a continued increase in incidence has been observed over recent years. Globally, there are approximately 750,000 new cases of liver cancer reported each year. Importantly, population-based studies show that HCC ranks as the third leading cause of cancer-related deaths worldwide.

4 Dec 2014

UC Berkeley scientists reveal how humans have excelled at 'relational reasoning'

When it comes to getting out of a tricky situation, we humans have an evolutionary edge over other primates. Take, as a dramatic example, the Apollo 13 voyage in which engineers, against all odds, improvised a chemical filter on a lunar module to prevent carbon dioxide buildup from killing the crew.

4 Dec 2014

Researchers publish first comprehensive characterization of genetic diversity in Sub-Saharan Africa

Researchers from the African Genome Variation Project have published the first attempt to comprehensively characterise genetic diversity across Sub-Saharan Africa. The study of the world's most genetically diverse region will provide an invaluable resource for medical researchers and provides insights into population movements over thousands of years of African history.

4 Dec 2014

Researchers receive grant to examine role of proteins in dementia diseases

Researchers from Plymouth University Peninsula Schools of Medicine and Dentistry have received funding from Alzheimer's charity BRACE for a pilot study to investigate the role of proteins in the development of dementia diseases such as Alzheimer's and Parkinson's.

4 Dec 2014

Protein that regulates the body's sleep cycle may offer cancer protection

People who work around the clock could actually be setting themselves back, according to Virginia Tech biologists.

4 Dec 2014

Resveratrol in red wine may prevent cancer

Alcohol use is a major risk factor for head and neck cancer. But an article published in the November issue of the journal Advances in Experimental Medicine and Biology shows that the chemical resveratrol found in grape skins and in red wine may prevent cancer as well.

4 Dec 2014

Tobacco smoke toxin could increase pain in people with spinal cord injury

A neurotoxin called acrolein found in tobacco smoke that is thought to increase pain in people with spinal cord injury has now been shown to accumulate in mice exposed to the equivalent of 12 cigarettes daily over a short time period.

4 Dec 2014

Scientists report new approach to defeating asthma by targeting allergen

Current asthma treatments can alleviate wheezing, coughing and other symptoms felt by millions of Americans every year, but they don't get to the root cause of the condition. Now, for the first time, scientists are reporting a new approach to defeating asthma by targeting the trigger -- the allergen -- before it can spark an attack. They describe their new compound, which they tested on rats, in ACS' Journal of Medicinal Chemistry.

3 Dec 2014

Organovo, Yale collaborate to develop bioprinted tissues for surgical transplantation research

Organovo Holdings, Inc., a three-dimensional biology company focused on delivering breakthrough 3D bioprinting technology, and Yale School of Medicine, Department of Surgery have formed a collaboration to develop bioprinted tissues for surgical transplantation research, made possible by a generous gift from the Methuselah Foundation.

3 Dec 2014

Human stem cells made from adult donor cells remember their origin, say McMaster scientists

Scientists at McMaster University have discovered that human stem cells made from adult donor cells "remember" where they came from and that's what they prefer to become again.

3 Dec 2014

Rhine-Waal students bag first place in research poster competition at European Detergents Conference

Rhine-Waal students Aleksandar Hizman, Sabine Vollmer, Chantal Baumann, Kim Krieger and Lars Frohn, undergraduates in the Quality, Environment, Safety and Hygiene programme of the Faculty of Life Sciences, won first place in a research poster competition at the 10th annual European Detergents Conference, held in conjunction with the SEPAWA Congress in Fulda, Germany.

3 Dec 2014

MIT engineers create new computer model to design complex 3-D DNA shapes

MIT biological engineers have created a new computer model that allows them to design the most complex three-dimensional DNA shapes ever produced, including rings, bowls, and geometric structures such as icosahedrons that resemble viral particles.

3 Dec 2014

Scientists develop system for printing protein patterns onto film

Protein-coated Petri dishes are increasingly being used to support cell growth during cell cultivation. Scientists have developed a system for printing protein patterns onto film using a roll-to-roll process, which allows high volumes to be manufactured efficiently and cost-effectively.

3 Dec 2014

Researchers use MRI techniques to study consequences of anorexia nervosa on brain structure

Researchers from the Translational Developmental Neuroscience Lab led by Professor Stefan Ehrlich at the Department of Child and Adolescent Psychiatry and Psychotherapy of the University Hospital Carl Gustav Carus at the TU Dresden (Faculty of Medicine) used state-of-the-art magnetic resonance imaging (MRI) techniques to investigate the consequences of anorexia nervosa on brain structure.

3 Dec 2014

Medical Science News

New technology reveals cellular gene transcription process in detail

Controlling neural excitations may help prevent detrimental effects like those in stroke, say scientists

New light-triggered strategy can provide accurate control over aptamer-based therapeutics

New chemical compound shows promise in restoring function lost to spinal cord injury

UAB research suggests potential therapeutic target for patients with frontotemporal dementia

Researchers identify biochemical mechanism that could lead to 'chemo brain'

Scientists review HBV-associated tumor microenvironment in hepatocellular carcinoma

UC Berkeley scientists reveal how humans have excelled at 'relational reasoning'

Researchers publish first comprehensive characterization of genetic diversity in Sub-Saharan Africa

Researchers receive grant to examine role of proteins in dementia diseases

Protein that regulates the body's sleep cycle may offer cancer protection

Resveratrol in red wine may prevent cancer

Tobacco smoke toxin could increase pain in people with spinal cord injury

Scientists report new approach to defeating asthma by targeting allergen

Organovo, Yale collaborate to develop bioprinted tissues for surgical transplantation research

Human stem cells made from adult donor cells remember their origin, say McMaster scientists

Rhine-Waal students bag first place in research poster competition at European Detergents Conference

MIT engineers create new computer model to design complex 3-D DNA shapes

Scientists develop system for printing protein patterns onto film

Researchers use MRI techniques to study consequences of anorexia nervosa on brain structure

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