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UCLA scientists develop statistical method for conducting survival analysis of cancer patients

People with cancer are often told by their doctors approximately how long they have to live, and how well they will respond to treatments, but what if there were a way to improve the accuracy of doctors' predictions?

9 Jun 2016

Scientists resuscitate efforts to crack KRas protein structures

In the annals of cancer research, a protein known as KRas has become notorious. Part of a family of proteins implicated in 30 percent of cancers, KRas is considered a highly desirable but defiant drug target.

9 Jun 2016

Study provides insights into new pathways to generate universal vaccine against influenza viruses

Diverse antibodies induced in humans by vaccination with an avian influenza virus vaccine may offer broader, more durable protection against multiple strains of influenza than today's vaccines typically provide, according to a study led by Florian Krammer, PhD, Assistant Professor in the Department of Microbiology at the Icahn School of Medicine at Mount Sinai, and Patrick Wilson, PhD, Associate Professor in the Department of Medicine at the University of Chicago.

9 Jun 2016

Whole-exome sequencing can help characterize genetic alterations for commonly used bladder cancer cell lines

Much of basic cancer research is based on studies with cultured cancer cells. However, the usefulness of these studies greatly depends on how accurately these cancer cells grown in a dish represent human tumors.

9 Jun 2016

New effort in biomedical engineering may improve heart repair

Jianyi "Jay" Zhang, M.D., Ph.D., brought his biomedical engineering expertise to the University of Alabama at Birmingham to fix hearts.

9 Jun 2016

Drug candidate delivered by plant-virus-based carrier shows promise for triple-negative breast cancer

In a pair of firsts, researchers at Case Western Reserve University and Massachusetts Institute of Technology have shown that the drug candidate phenanthriplatin can be more effective than an approved drug in vivo, and that a plant-virus-based carrier successfully delivers a drug in vivo.

9 Jun 2016

Natural material in plants can enhance performance of sunscreens

Warm weather means beach vacations and pool-dipping for many of us. It also signals a season of slathering on sunscreen to avoid getting burned. Someday, those products could be enhanced with lignin, a natural material in plants and a major waste product of the paper industry.

9 Jun 2016

Scientists explore effects of physiological fluid shear on dangerous type of Salmonella

Once inside the human body, infectious microbes like Salmonella face a fluid situation. They live in a watery world, surrounded by liquid continually flowing over and abrading their cell surfaces--a property known as fluid shear.

9 Jun 2016

Far-UVC light can combat deadly scourge of drug-resistant surgical site infections

Scientists from the Center for Radiological Research at Columbia University Medical Center have shown that a narrow wavelength of ultraviolet (UV) light safely killed drug-resistant MRSA bacteria in mice, demonstrating a potentially safe and cost-effective way to reduce surgical site infections, a major public health concern.

9 Jun 2016

Transplantation of hpNSCs into non-human primates modeled with PD promotes behavioral recovery

A multi-center team of researchers in the U.S. testing the potential of cell therapy for treating Parkinson's disease (PD) has found that grafting human parthenogenetic stem cell-derived neural stem cells (hpNSCs) into non-human primates modeled with PD promoted behavioral recovery, increased dopamine concentrations in the brain, and induced the expression of beneficial genes and pathways when compared to control animals not transplanted with stem cells.

9 Jun 2016

Researchers identify promising new compound for targeting triple-negative breast cancer

Researchers at the University of Michigan have identified a promising new compound for targeting one of the most aggressive types of breast cancer.

9 Jun 2016

Simple blood test can help track rising levels of eosinophils linked to regrowth of sinus polyps

In an effort to identify a simple, reliable way to track the course of nasal polyps in chronic sinus disease, Johns Hopkins Medicine researchers say they've linked rising levels of immune system white blood cells, called eosinophils, with regrowth of polyps removed by surgery.

9 Jun 2016

Metabolite of oral DMF drug for multiple sclerosis appears to slow onset of Parkinson's disease

The metabolite of a drug that is helping patients battle multiple sclerosis appears to significantly slow the onset of Parkinson's disease, researchers say.

9 Jun 2016

Understanding DNA scrunching could help develop novel ways to fight infections

Evidence of DNA "scrunching" may one day lead to a new class of drugs against viruses, according to a research team from the Perelman School of Medicine at the University of Pennsylvania, the Georgia Institute of Technology, and Columbia University.

9 Jun 2016

Age may play major role in cell's ability to respond to physical exercise

If you're an older adult, a 30-minute workout may not be as effective, even at the cellular level, as it was when you were younger.

9 Jun 2016

Researchers investigate causes of renal failure using mathematical model

No one can deny that open-heart surgery, where the heart is exposed and the blood is made to bypass it, is one of the most invasive of all medical procedures. Nearly a third of all patients undergoing heart surgery experience kidney failure, yet little is known about why kidney injury occurs or how to prevent it.

9 Jun 2016

Medical Science News

UCLA scientists develop statistical method for conducting survival analysis of cancer patients

Scientists resuscitate efforts to crack KRas protein structures

Study provides insights into new pathways to generate universal vaccine against influenza viruses

Whole-exome sequencing can help characterize genetic alterations for commonly used bladder cancer cell lines

New effort in biomedical engineering may improve heart repair

Drug candidate delivered by plant-virus-based carrier shows promise for triple-negative breast cancer

Natural material in plants can enhance performance of sunscreens

Scientists explore effects of physiological fluid shear on dangerous type of Salmonella

Far-UVC light can combat deadly scourge of drug-resistant surgical site infections

Transplantation of hpNSCs into non-human primates modeled with PD promotes behavioral recovery

Researchers identify promising new compound for targeting triple-negative breast cancer

Simple blood test can help track rising levels of eosinophils linked to regrowth of sinus polyps

Metabolite of oral DMF drug for multiple sclerosis appears to slow onset of Parkinson's disease

Understanding DNA scrunching could help develop novel ways to fight infections

Age may play major role in cell's ability to respond to physical exercise

Researchers investigate causes of renal failure using mathematical model

Researchers deploy mobile DNA sequencing laboratories to help combat Zika virus spread in Brazil

New technology can detect KRAS gene mutations, facilitate targeted therapies for lung and colorectal cancers

Researchers identify lymphatic endothelial lineage that shows potential for new anti-cancer treatment

B lymphocytes can influence psoriasis by regulating cytokine IL-10

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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