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Researchers develop new nanorobotic agents to deliver drugs by targeting cancerous tumours

Researchers from Polytechnique Montréal, Université de Montréal and McGill University have just achieved a spectacular breakthrough in cancer research.

16 Aug 2016

Study shows leptomeningeal metastases more prevalent in NSCLC patients with EGFR mutations

Leptomeningeal metastases (LM), a devastating complication and predictor of poor survival in lung cancer patients, was found to be more prevalent in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations.

16 Aug 2016

Healthy BMI, exercise and diet can lower abnormal protein build-ups linked to Alzheimer’s

A study by researchers at UCLA's Semel Institute for Neuroscience and Human Behavior has found that a healthy diet, regular physical activity and a normal body mass index can reduce the incidence of protein build-ups that are associated with the onset of Alzheimer's disease.

16 Aug 2016

Microscale and macroscale brain disruptions may emerge together in schizophrenia

Brain abnormalities in schizophrenia have been identified at the microscale (alterations in synaptic connections between neurons) and the macroscale (altered connections between brain regions).

16 Aug 2016

Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

Using technology they developed, UT Southwestern Medical Center researchers have identified a previously unknown role of a certain class of proteins: as regulators of gene activity and RNA processing.

16 Aug 2016

German scientists develop new approach to prevent GvHD after bone marrow transplants

Scientists in Germany have developed a new approach that may prevent leukemia and lymphoma patients from developing graft-versus-host disease (GvHD) after therapeutic bone marrow transplants.

16 Aug 2016

Increased parental longevity linked to lower risk of cardiovascular conditions in offspring

In middle aged populations, the risks of cardiovascular conditions are progressively lower the longer a person's parents lived past 69 years old, according to a study of 186,000 participants using a voluntary database published today in the Journal of the American College of Cardiology.

16 Aug 2016

New, non-invasive way to monitor progression of Parkinson's disease may help improve treatment

A new, non-invasive way to track the progression of Parkinson's disease could help evaluate experimental treatments to slow or stop the disease's progression.

16 Aug 2016

Study offers clues about how genetic mutations can increase risk of psychiatric disorders

Brain scans have revealed how a genetic mutation linked to major psychiatric disorders affects the structure, function and chemistry of the brain.

16 Aug 2016

Scientists find new way to use CRISPR gene editing to help fix sickle cell disease

An international team of scientists led by researchers at St. Jude Children's Research Hospital has found a way to use CRISPR gene editing to help fix sickle cell disease and beta-thalassemia in blood cells isolated from patients.

16 Aug 2016

New study uncovers how chromosomal changes impact tumor formation and growth

As with most cancers, triple-negative breast cancer (TNBC) cells have abnormal amounts of chromosomes or DNA copy number aberrations (CNAs) in their genomes.

16 Aug 2016

TUM scientists isolate and archive cultured bacterial strains from mouse microbiome

Mouse models are extensively used in pharmaceutical and medical research, and it is known that the communities of microbes in their intestine can have a significant impact on the research output.

12 Aug 2016

St. Jude scientists identify key innate immune sensor that attacks influenza virus

St. Jude Children's Research Hospital immunologists have identified the protein trigger in the body's quick-reaction innate immune system that specifically recognizes the influenza virus in infected cells and triggers their death.

12 Aug 2016

Glia cells may play role in regulating sugar intake into the brain, experts report

Researchers at Technical University of Munich discovered that our brain actively takes sugar from the blood. Prior to this, researchers around the world had assumed that this was a purely passive process.

12 Aug 2016

Intestinal flora likely to have effect on person's response to drugs

Intestinal flora has multiple influences on human health, but researchers have revealed that it is also likely to have an effect on the body's response to drugs.

12 Aug 2016

Former SpaceX engineers launch Synthego, CRISPRevolution to accelerate genome engineering research

Synthego, a leading provider of genome engineering solutions, officially launches today. Synthego’s flagship product line, CRISPRevolution, features synthetic guide RNA products designed to accelerate CRISPR/Cas9 and Cpf1 genome engineering research. CRISPRevolution is the first product line to offer economical access to fully synthetic RNA for high fidelity editing and increased precision in genome editing.

12 Aug 2016

ICR researchers identify how genetic variant linked to leukaemia helps cancer cells survive

Scientists at The Institute of Cancer Research, London, have identified how an inherited genetic variant, associated with an increased risk of developing the most common type of leukaemia, helps cancer cells survive. The findings could lead to new ways to target the disease.

12 Aug 2016

EPFL scientists develop new method to cheaply produce chemical compounds

EPFL scientists design a new method to cheaply produce some of the most important chemical compounds in the pharmaceutical industry - the amines.

12 Aug 2016

FDA grants Orphan Drug Designation to CD4CAR therapy for treatment of peripheral T-cell lymphoma

iCell Gene Therapeutics today (Aug. 11) announced that the Food and Drug Administration has granted Orphan Drug Designation for its chimeric antigen receptor engineered T-cells directed against the target protein CD4 (CD4CAR) for the treatment of peripheral T-cell lymphoma (PTCL).

12 Aug 2016

Specific molecular features control uptake of biguanides into mitochondria to inhibit respiration

The biguanides are a family of drugs with diverse clinical applications. Metformin, a widely used anti-hyperglycemic biguanide, suppresses mitochondrial respiration by inhibiting respiratory complex I. Phenformin, a related anti-hyperglycemic biguanide, also inhibits respiration, but proguanil, which is widely used for the prevention of malaria, does not.

12 Aug 2016

Medical Science News

Researchers develop new nanorobotic agents to deliver drugs by targeting cancerous tumours

Study shows leptomeningeal metastases more prevalent in NSCLC patients with EGFR mutations

Healthy BMI, exercise and diet can lower abnormal protein build-ups linked to Alzheimer’s

Microscale and macroscale brain disruptions may emerge together in schizophrenia

Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

German scientists develop new approach to prevent GvHD after bone marrow transplants

Increased parental longevity linked to lower risk of cardiovascular conditions in offspring

New, non-invasive way to monitor progression of Parkinson's disease may help improve treatment

Study offers clues about how genetic mutations can increase risk of psychiatric disorders

Scientists find new way to use CRISPR gene editing to help fix sickle cell disease

New study uncovers how chromosomal changes impact tumor formation and growth

TUM scientists isolate and archive cultured bacterial strains from mouse microbiome

St. Jude scientists identify key innate immune sensor that attacks influenza virus

Glia cells may play role in regulating sugar intake into the brain, experts report

Intestinal flora likely to have effect on person's response to drugs

Former SpaceX engineers launch Synthego, CRISPRevolution to accelerate genome engineering research

ICR researchers identify how genetic variant linked to leukaemia helps cancer cells survive

EPFL scientists develop new method to cheaply produce chemical compounds

FDA grants Orphan Drug Designation to CD4CAR therapy for treatment of peripheral T-cell lymphoma

Specific molecular features control uptake of biguanides into mitochondria to inhibit respiration

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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