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Researchers find Aspergillus as interesting target for discovery of novel drugs

The fungus Aspergillus fumigatus produces a group of previously unknown natural products. With reference to plant isoquinoline alkaloids, these substances have been named fumisoquins.

28 May 2016

Growing opportunities for artificial brain enhancement bring humans closer to becoming cyborgs

Our excitement with and rapid uptake of technology - and the growing opportunities for artificial brain enhancement - are putting humans more firmly on the path to becoming cyborgs, according to evolution experts from the University of Adelaide.

28 May 2016

University of Leicester researcher awarded grant to develop bacteriophages to target infant Shigella

A University of Leicester researcher has been awarded funding to develop bacteriophages to target bacterial infant diarrhoea in the developing world where it causes significant mortality.

28 May 2016

OIST scientists reveal how big protein complex inside E. coli cells divide and multiply

Escherichia coli (E. coli) are bacteria that live all around and inside of us. Most E. coli are harmless, but some strains can cause illness, and can even, in extreme cases, be deadly. With recent outbreaks of E. coli around the world, there is a fear of acquiring an infection from these bacteria.

28 May 2016

Slime mold provides key to understanding directional ability of immune cells

How white blood cells in our immune systems home in on and engulf bacterial invaders--like humans following the scent of oven-fresh pizza--has long been a mystery to scientists.

28 May 2016

New, simpler way for encapsulation-free controlled protein release

A U of T Engineering team has designed a simpler way to keep therapeutic proteins where they are needed for long periods of time. The discovery is a potential game-changer for the treatment of chronic illnesses or injuries that often require multiple injections or daily pills.

28 May 2016

Researchers demonstrate decisive role of cholesterol in T cell activation

T cell receptors are an important part of the human immune system. They are able to switch their conformation from an inactive to an active state spontaneously without any antigens present.

28 May 2016

Study finds link between respiratory sinus arrhythmia and survival prospects of heart attack patients

The heart rate may be an indicator of a person's life expectancy. A research team at the Technical University of Munich has to this end analyzed an effect which at first seems paradoxical: Minor irregularities in the heartbeat are indicative of a healthy body.

28 May 2016

New CRISPR-EZ method makes genome editing much easier in mice

University of California, Berkeley scientists have developed a quicker and more efficient method to alter the genes of mice with CRISPR-Cas9, simplifying a procedure growing in popularity because of the ease of using the new gene-editing tool.

28 May 2016

NASA releases new video that highlights Mark and Scott Kelly's metabolites

NASA's Human Research Program is releasing "Metabolomics: You Are What You Eat" video to highlight its Twins Study which uses omics to study Mark and Scott Kelly's metabolites.

28 May 2016

Certain HLA genes may increase ovarian cancer risk in women

Researchers in the Center for Immunotherapy at Roswell Park Cancer Institute have evaluated the human leukocyte antigen (HLA), a group of genes that help regulate the body's immune system, for underlying differences in ovarian cancer patients' response to therapy.

28 May 2016

New player in calcium signalling pathways acts as molecular brake to Orai activation

Information flow in cells relies on calcium as a key agent in several signalling pathways. Calcium dependent signalling is crucial in nearly every aspect of life - muscle movement, immune reactions, nerve function, light sensing and many such processes.

28 May 2016

Imaging data shows brains may have capacity to reverse schizophrenia effects

A team of scientists from across the globe have shown that the brains of patients with schizophrenia have the capacity to reorganize and fight the illness. This is the first time that imaging data has been used to show that our brains may have the ability to reverse the effects of schizophrenia.

28 May 2016

Applying deep neural networks to predict pharmacologic properties of drugs and drug repurposing

Deep learning, frequently referred to as artificial intelligence, a branch of machine learning utilizing multiple layers of neurons to model high-level abstractions in data, has outperformed humans in tasks including image, text and voice recognition, autonomous driving and others, and is now being applied to drug discovery and biomarker development.

28 May 2016

Study identifies potential new treatment for subset of gastric cancer patients

Testing cancers for 'addiction' to a gene that boosts cell growth can pick out patients who may respond to a targeted drug under development, a major new study reports.

28 May 2016

Researchers discover ANKRD55 gene linked to multiple sclerosis

The Ikerbasque researcher Koen Vandenbroeck, who heads the Neurogenomiks laboratory which reports to the Achucarro centre and the UPV/EHU-University of the Basque Country, together with other national and international groups, has shown that a genetic variant in the 5q11 chromosome, which is associated with susceptibility to developing multiple sclerosis, greatly regulates a gene known as ANKRD55. ANKRD55 is a gene with an unknown function.

28 May 2016

Increasing specific microRNA levels can restore chemotherapy sensitivity in pancreatic cancer cells

By increasing the level of a specific microRNA (miRNA) molecule, researchers have for the first time restored chemotherapy sensitivity in vitro to a line of human pancreatic cancer cells that had developed resistance to a common treatment drug.

27 May 2016

NR supplements can reduce diabetes-related complications in mice

A naturally occurring vitamin, nicotinamide riboside (NR), can lower blood sugar levels, reduce fatty liver, and prevent peripheral nerve damage in mouse models of prediabetes and type 2 diabetes (T2D), according to a new study by researchers at the University of Iowa and the Iowa City VA Health Care System.

27 May 2016

Study finds that TPC2 protein regulates melanin production

A year and a half ago, researchers at Brown University found a molecular gas pedal for melanin production. Now they've found a brake. For scientists, the finding deepens not only the basic understanding of how eyes, skin and hair gain color, but also what perhaps can be done in disorders, such as albinism, when that doesn't happen.

27 May 2016

New understanding of neurotransmitter transporter mechanism gives hope for treating depression, addicition

When nerve cells have to communicate with each other in our brains, it involves release of small signal molecules, the so-called neurotransmitters, which act as chemical messengers in specific points of contact between nerve cells, called synapses.

27 May 2016

Medical Science News

Researchers find Aspergillus as interesting target for discovery of novel drugs

Growing opportunities for artificial brain enhancement bring humans closer to becoming cyborgs

University of Leicester researcher awarded grant to develop bacteriophages to target infant Shigella

OIST scientists reveal how big protein complex inside E. coli cells divide and multiply

Slime mold provides key to understanding directional ability of immune cells

New, simpler way for encapsulation-free controlled protein release

Researchers demonstrate decisive role of cholesterol in T cell activation

Study finds link between respiratory sinus arrhythmia and survival prospects of heart attack patients

New CRISPR-EZ method makes genome editing much easier in mice

NASA releases new video that highlights Mark and Scott Kelly's metabolites

Certain HLA genes may increase ovarian cancer risk in women

New player in calcium signalling pathways acts as molecular brake to Orai activation

Imaging data shows brains may have capacity to reverse schizophrenia effects

Applying deep neural networks to predict pharmacologic properties of drugs and drug repurposing

Study identifies potential new treatment for subset of gastric cancer patients

Researchers discover ANKRD55 gene linked to multiple sclerosis

Increasing specific microRNA levels can restore chemotherapy sensitivity in pancreatic cancer cells

NR supplements can reduce diabetes-related complications in mice

Study finds that TPC2 protein regulates melanin production

New understanding of neurotransmitter transporter mechanism gives hope for treating depression, addicition

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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