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Myriad Genetics' Tumor BRACAnalysis CDx identifies 44% more candidates for PARP therapy

Myriad Genetics, Inc. today announced that its Tumor BRACAnalysis CDx- companion diagnostic test significantly improved the detection of cancer-causing BRCA1/2 mutations by 44 percent in women with ovarian cancer. Data from this new study were presented at the 2014 European Society for Medical Oncology annual meeting in Madrid, Spain.

29 Sep 2014

Scientists reveal that human brain can trigger random behavior

Many of the choices we make are informed by experiences we've had in the past. But occasionally we're better off abandoning those lessons and exploring a new situation unfettered by past experiences.

29 Sep 2014

Scientists discover mechanism that resists cancer drugs in estrogen-positive breast cancer

Scientists have discovered a previously unknown mechanism by which estrogen prepares cells to divide, grow and, in the case of estrogen-positive breast cancers, resist cancer drugs. The researchers say the work reveals new targets for breast cancer therapy and will help doctors predict which patients need the most aggressive treatment.

29 Sep 2014

Researchers create new Cas9 animal model for in vivo genome editing experiments

Researchers from the Broad Institute and Massachusetts Institute of Technology have created a new mouse model to simplify application of the CRISPR-Cas9 system for in vivo genome editing experiments.

29 Sep 2014

New study exposes negative consequences of sleep deprivation among teens

While American paediatricians warn sleep deprivation can stack the deck against teenagers, a new study from Taylor & Francis reveals youth's irritability and laziness aren't down to attitude problems but lack of sleep.

29 Sep 2014

Understanding how neurons encode information

Nathan Urban, interim provost and the Dr. Frederick A. Schwertz Distinguished Professor of Life Sciences, and Robert Kass, professor of statistics and machine learning, have received a $930,000 grant from the National Science Foundation to apply biological and statistical neuroscience approaches in order to create a better overall understanding of how neurons encode information.

29 Sep 2014

Study provides support for new understanding of the immune system

A study published in the journal Science provides support for a new-and still controversial-understanding of the immune system. The research was conducted by collaborators in the U.S. and Europe, including Robert Cramer, PhD, an assistant professor of microbiology and immunology at the Geisel School of Medicine and member of the Dartmouth Lung Biology Center, and Kelly Shepherdson, PhD, at the time a graduate student in Cramer's lab.

29 Sep 2014

New, high-throughput method can sort 10 billion bacterial cells in 30 minutes

University of Hawaii at Manoa College of Engineering mechanical engineer Yi Zuo has developed a new, high-throughput method for sorting cells capable of separating 10 billion bacterial cells in 30 minutes.

29 Sep 2014

Dr. Nancy Chiaravalloti of Kessler Foundation receives Alumni Achievement in Science award

Nancy (Donofrio) Chiaravalloti, PhD, of Kessler Foundation received the Alumni Achievement in Science award from her alma mater, Muhlenberg College at the Alumni Association luncheon on September 13th.

27 Sep 2014

New findings could pave way for treating autoimmune diseases

Scientists from A*STAR's Bioprocessing Technology Institute (BTI) have established a clearer relationship between two cells which serve our body's natural defence mechanisms against diseases and infections.

26 Sep 2014

MIT researchers use disarmed version of anthrax toxin to deliver cancer drugs

Bacillus anthracis bacteria have very efficient machinery for injecting toxic proteins into cells, leading to the potentially deadly infection known as anthrax. A team of MIT researchers has now hijacked that delivery system for a different purpose: administering cancer drugs.

26 Sep 2014

Imperial scientists map proteins affected by NMT enzyme, suggest potential way to treat cancer

Imperial chemists have gained fresh insights into how a disease-causing enzyme makes changes to proteins and how it can be stopped.

26 Sep 2014

UMass Amherst cell biologists propose new detailed cytokinesis model

Along with copying and splitting DNA during division, cells must have a way to break safely into two viable daughter cells, a process called cytokinesis. But the molecular basis of how plant cells accomplish this without mistakes has been unclear for many years.

26 Sep 2014

Scientists discover new clues about drug used in treating blood cancer

Keck Medicine of USC scientists have discovered new clues about a drug instrumental in treating a certain blood cancer that may provide important targets for researchers searching for cures.

26 Sep 2014

Research findings provide clues for design of future HIV vaccine

Scientists at The Scripps Research Institute have described how a single family of antibodies that broadly neutralizes different strains of HIV has evolved remarkably diverse structures to attack a vulnerable site on the virus.

26 Sep 2014

BRD4 protein appears to play key role in keeping stem cells in immature "pluripotent" state

A protein implicated in several cancers appears to play a pivotal role in keeping stem cells in an immature "pluripotent" state, according to a new study by NYU Langone Medical Center scientists.

26 Sep 2014

International researchers identify novel causes for severe childhood epilepsies

In the largest collaborative study so far, an international team of researchers, including scientists from VIB and Antwerp University identified novel causes for severe childhood epilepsies.

26 Sep 2014

Researchers awarded $16 million NIMH grant to create genetic resource for psychiatric disorders

A multi-institutional team of researchers studying schizophrenia and bipolar disorder has been awarded a $16 million grant from the National Institute of Mental Health to create the most extensive genetic resource to date for these two devastating psychiatric disorders, using data assembled by the University of Southern California.

26 Sep 2014

Two genes that cause pediatric glaucoma increases risk of future stroke up to ten times

Every year in Canada about 50,000 people suffer from a stroke, caused either by the interruption of blood flow or uncontrolled bleeding in the brain. While many environmental risk factors exist, including high blood pressure and smoking, stroke risk is also frequently inherited. Unfortunately, remarkably little is known regarding stroke's genetic basis.

26 Sep 2014

Study findings have potential to advance treatments for small cell lung cell cancer

Two recently published studies by a research team at University Hospitals Case Medical Center Seidman Cancer Center have the potential to advance treatments for small cell lung cell cancer (SCLC). This aggressive form of lung cancer has seen no treatment advances in 30 years and "is a disease in urgent need of new drug therapies," write the study's authors.

26 Sep 2014

Medical Science News

Myriad Genetics' Tumor BRACAnalysis CDx identifies 44% more candidates for PARP therapy

Scientists reveal that human brain can trigger random behavior

Scientists discover mechanism that resists cancer drugs in estrogen-positive breast cancer

Researchers create new Cas9 animal model for in vivo genome editing experiments

New study exposes negative consequences of sleep deprivation among teens

Understanding how neurons encode information

Study provides support for new understanding of the immune system

New, high-throughput method can sort 10 billion bacterial cells in 30 minutes

Dr. Nancy Chiaravalloti of Kessler Foundation receives Alumni Achievement in Science award

New findings could pave way for treating autoimmune diseases

MIT researchers use disarmed version of anthrax toxin to deliver cancer drugs

Imperial scientists map proteins affected by NMT enzyme, suggest potential way to treat cancer

UMass Amherst cell biologists propose new detailed cytokinesis model

Scientists discover new clues about drug used in treating blood cancer

Research findings provide clues for design of future HIV vaccine

BRD4 protein appears to play key role in keeping stem cells in immature "pluripotent" state

International researchers identify novel causes for severe childhood epilepsies

Researchers awarded $16 million NIMH grant to create genetic resource for psychiatric disorders

Two genes that cause pediatric glaucoma increases risk of future stroke up to ten times

Study findings have potential to advance treatments for small cell lung cell cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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