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Researchers find new way to prevent graft-versus-host disease after stem cell transplants

Through experimental work, an international team of researchers led by City of Hope's Defu Zeng, professor of diabetes immunology and hematopoietic cell transplantation, believe they may have found a way to prevent graft-versus-host disease after stem cell transplants while retaining the transplants' positive effects on fighting leukemia and lymphoma.

18 Apr 2017

Air pollution may directly affect biology of upper airways to cause chronic sinus problems

Although human population studies have linked air pollution to chronic inflammation of nasal and sinus tissues, direct biological and molecular evidence for cause and effect has been scant.

18 Apr 2017

Healthcare for mental illness is on the decline in US, say experts

More Americans than ever before are suffering from serious psychological distress (SPD), according to researchers from NYU Langone Medical Center.

18 Apr 2017

UTHealth researchers identify less invasive way to screen for colorectal cancer

Specific strains of bacteria in the gut are significantly associated with colorectal cancer, according to a new study by researchers at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health.

18 Apr 2017

Study shows how early administration of old drug reduces damage during heart attack

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have discovered a new mechanism of action of metoprolol, a drug that can reduce the damage produced during a heart attack if administered early.

18 Apr 2017

Innovate UK funds new, economic vaccine to halt spread of 'zoonotic' infectious diseases

A team of international scientists led by Dr. Michael Jarvis at the University of Plymouth has received funding in excess of £408,000 from Innovate UK to develop a new and economic vaccine designed to halt the spread of highly pathogenic 'zoonotic' (spreading from animals to humans) infectious diseases.

18 Apr 2017

New 7-gene test strategy could improve life expectancy for women at risk of hereditary breast cancer

Value in Health, the official journal of the International Society for Pharmacoeconomics and Outcomes Research, announced today the publication of new research indicating that testing for variants in 7 cancer-associated genes (versus the usual process of testing in just 2 genes) followed by risk-reduction management could cost-effectively improve life expectancy for women at risk of hereditary breast cancer.

17 Apr 2017

Study establishes potential of BAT receptors as druggable targets for treatment of obesity, diabetes

According to research published online in The FASEB Journal, scientists have discovered a way to increase the amount of metabolism-boosting brown adipose tissue (BAT) ("good" fat) by employing two receptors on BAT cells as potential therapeutic targets.

17 Apr 2017

Microscopic probes simplify process of measuring electrical signals in small animals

Microscopic probes developed at Rice University have simplified the process of measuring electrical activity in individual cells of small living animals. The technique allows a single animal like a worm to be tested again and again and could revolutionize data-gathering for disease characterization and drug interactions.

17 Apr 2017

Nanoparticle-programmed immune cells can slow progression of leukemia in mouse model

Researchers at Fred Hutchinson Cancer Research Center have developed biodegradable nanoparticles that can be used to genetically program immune cells to recognize and destroy cancer cells -- while the immune cells are still inside the body.

17 Apr 2017

Discovery of additional viral reservoir reveals new target for HIV cure research

HIV cure research to date has focused on clearing the virus from T cells, a type of white blood cell that is an essential part of the immune system.

17 Apr 2017

Gambling addicts have poor ability to assess and adapt to high risk situations, fMRI study finds

You've been losing all night, and now another bad hand. So why raise? Gambling addiction is a mental disorder characterized by excessive risk-taking despite negative results. Scientific studies using functional MRI -- fMRI, a method of looking at active areas of the brain -- have previously shown that addicts have altered activity in brain regions related to risk and reward, making them prone to prefer risky choices.

17 Apr 2017

Th17 cell durability offers promise for next-generation adoptive cancer immunotherapy trials

Medical University of South Carolina investigators report that long-term expansion protocols for adoptive cancer immunotherapy do not compromise Th17 cells' effectiveness against large tumors, in the March 9, 2017 issue of JCI Insight.

17 Apr 2017

Scientists identify gene responsible for generating key lipid in skin barrier formation

Scientists have identified the gene responsible for generating acylceramide, the key lipid in forming the skin barrier that protects us from pathogens, allergens and other harmful substances. This finding could prove crucial in developing medicines for treating atopic dermatitis and ichthyosis.

17 Apr 2017

Study describes synthesis and biological evaluation of novel, effective ARIs

Diabetes mellitus (DM) is probably one of the oldest known diseases and the incidence has been increasing steadily all over the world. This metabolic disease is characterized by chronic hyperglycemia due to defect in insulin secretion and/or insulin action.

17 Apr 2017

Vaccine-chemotherapy combination may improve survival for glioblastoma patients

A vaccine targeting cytomegalovirus (CMV) antigen pp65, combined with high-dose chemotherapy (temozolomide), improved both progression-free survival and overall survival for a small group of glioblastoma (GBM) patients.

17 Apr 2017

Seeing genes inside living cells

For Mazhar Adli, the little glowing dots dancing about on the computer screen are nothing less than the fulfillment of a dream. Those fluorescent dots, moving in real time, are set to illuminate our understanding of the human genome, cancer and other genetic diseases in a way never before possible.

14 Apr 2017

Medical Science News

Researchers find new way to prevent graft-versus-host disease after stem cell transplants

Air pollution may directly affect biology of upper airways to cause chronic sinus problems

Healthcare for mental illness is on the decline in US, say experts

UTHealth researchers identify less invasive way to screen for colorectal cancer

Study shows how early administration of old drug reduces damage during heart attack

Innovate UK funds new, economic vaccine to halt spread of 'zoonotic' infectious diseases

New 7-gene test strategy could improve life expectancy for women at risk of hereditary breast cancer

Study establishes potential of BAT receptors as druggable targets for treatment of obesity, diabetes

Microscopic probes simplify process of measuring electrical signals in small animals

Nanoparticle-programmed immune cells can slow progression of leukemia in mouse model

Discovery of additional viral reservoir reveals new target for HIV cure research

Gambling addicts have poor ability to assess and adapt to high risk situations, fMRI study finds

Th17 cell durability offers promise for next-generation adoptive cancer immunotherapy trials

Scientists identify gene responsible for generating key lipid in skin barrier formation

Study describes synthesis and biological evaluation of novel, effective ARIs

Vaccine-chemotherapy combination may improve survival for glioblastoma patients

Seeing genes inside living cells

Lower-face asymmetries may help identify early life stress

Injection drug use linked to increase in immune activation, says researcher

Peripheral arteries may be useful for assessing heart disease risk, study finds

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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