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Clinical study shows watercress extract inhibits carcinogen activation in cigarette smokers

Watercress extract taken multiple times a day significantly inhibits the activation of a tobacco-derived carcinogen in cigarette smokers, researchers at the University of Pittsburgh Cancer Institute, partner with UPMC Cancer Center, demonstrated in a phase II clinical trial presented today at the American Association for Cancer Research Annual Meeting in New Orleans.

21 Apr 2016

Vegetable-based polyphenol enhances wound healing

A research group led by Osaka University found a plant-based polyphenol, promotes the migration of Mesenchymal Stem Cells (MSCs) in blood circulation and accumulates them in damaged tissues to improve wound healing. It is anticipated that the results will be used for stem cell treatments for cutaneous disorders associated with various damage and lesions.

21 Apr 2016

Researchers reposition existing prazosin drug to combat glioblastoma

Treatments available for glioblastoma—malignant brain tumors—have little effect. An international collaboration led by the Laboratoire Neurosciences Paris-Seine tested active ingredients from existing medications and eventually identified one compound of interest, prazosin, on these tumors. Not only did it seem to be effective in this type of cancer, but it also acted on a signaling pathway that is common with other cancers.

21 Apr 2016

Testosterone may lead to greater heart attack risk in men than women

Testosterone might be involved in explaining why men have a greater risk of heart attacks than women of similar age, according to a study funded by the British Heart Foundation and the Biotechnology and Biological Sciences Research Council. The findings, published in the journal Scientific Reports, could lead to new therapies to help reduce heart attack risk.

21 Apr 2016

TNF-alpha protein involved in autoimmune diseases may also promote tissue healing

As its name suggests, inflammatory bowel disease, which afflicts more than 1.6 million Americans, involves chronic inflammation of all or some of the digestive tract. An autoimmune disease known to have a strong genetic component, its symptoms are abdominal cramps, bloody diarrhea, and fever and, sometimes, weight loss. IBD, which is a group of inflammatory conditions, includes Crohn's disease and ulcerative colitis.

21 Apr 2016

Caltech researchers map out pathways of neurons responsible for Parkinson's motor impairments

Because billions of neurons are packed into our brain, the neuronal circuits that are responsible for controlling our behaviors are by necessity highly intermingled. This tangled web makes it complicated for scientists to determine exactly which circuits do what. Now, using two laboratory techniques pioneered in part at Caltech, Caltech researchers have mapped out the pathways of a set of neurons responsible for the kinds of motor impairments--such as difficulty walking--found in patients with Parkinson's disease.

21 Apr 2016

Gladstone scientists bioengineer micro-scale heart tissues from stem cells

Scientists at the Gladstone Institutes have invented a new way to create three-dimensional human heart tissue from stem cells. The tissue can be used to model disease and test drugs, and it opens the door for a precision medicine approach to treating heart disease. Although there are existing techniques to make three-dimensional tissues from heart cells, the new method dramatically reduces the number of cells needed, making it an easier, cheaper, and more efficient system.

21 Apr 2016

Novel method could help analyze GWAS results for sporadic diseases

Using a novel method, Whitehead Institute researchers have determined how a non-coding mutation identified in genome-wide association studies can contribute to sporadic Parkinson's disease (PD). The approach could be used to analyze GWAS results for other sporadic diseases with genetic causes, such as multiple sclerosis, diabetes, and cancer.

21 Apr 2016

Low levels of 25-hydroxyvitamin D highly prevalent among children with type 1 diabetes

During the past two decades, vitamin D status, defined as serum concentration of 25-hydroxyvitamin D, has emerged as a predictor of key clinical outcomes including bone health, glucose metabolism, cardiovascular health, immune health and survival.

21 Apr 2016

Scientists find interaction between amyloid and tau proteins that cause brain damage linked with AD

For years, neuroscientists have puzzled over how two abnormal proteins, called amyloid and tau, accumulate in the brain and damage it to cause Alzheimer's disease (AD). Which one is the driving force behind dementia? The answer: both of them, according to a new study by researchers at the Douglas Mental Health University Institute.

21 Apr 2016

Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

Adolescents and young adults with a severe inherited immunodeficiency disorder improved following treatment with novel gene therapy developed at St. Jude Children's Research Hospital and at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. The results of this study appear today in the journal Science Translational Medicine.

21 Apr 2016

MAILES study finds link between fatty diets and sleep

University of Adelaide researchers have found that men who consume diets high in fat are more likely to feel sleepy during the day, to report sleep problems at night, and are also more likely to suffer from sleep apnea.

21 Apr 2016

Non-invasive test to diagnose EoE could replace need for repeated endoscopy

A non-invasive test to diagnose and monitor an inflammatory disease that injures the esophagus - called eosinophilic esophagitis or EoE - would replace the need for repeated endoscopy for a growing number of children and adults with this relatively new condition.

21 Apr 2016

Scientists aim to identify marker that could indicate aggressive basal cell skin cancer

Most basal cell skin cancers are easily removed -- those on the arm, leg or back. But when the cancer is on the eyelid or when it starts to invade surrounding tissue, it's no longer straightforward.

21 Apr 2016

BioTek Instruments, MilliporeSigma collaborate on integrated solution for long-term live cell experiments

BioTek Instruments is pleased to announce its collaboration with MilliporeSigma on an integrated solution for long-term live cell experiments and dynamic time-lapse analyses, including automated cell perfusion and imaging.

21 Apr 2016

Scientists identify genetic variants that may influence wellbeing, depression and neuroticism

An international group of more than 190 scientists who analyzed the genomes of 298,420 individuals have found genetic variants that may influence our sense of wellbeing, depression and neuroticism.

21 Apr 2016

Orthocell announces further validation of 'Cell Factory' concept for generation of bone, cartilage

Regenerative medicine company Orthocell Limited is pleased to announce further validation of ‘Cell Factory’ concepts for generating tissue specific growth factors and protein’s to aid in the healing and regeneration of bone, tendon and cartilage.

21 Apr 2016

Scientists evaluate phage-based therapy to battle antibiotic-resistant bacterial superbug infections

Flinders University scientists are looking to bacteriophages – highly specific viruses - as the as the best way to attack antibiotic-resistant bacterial superbug infections.

21 Apr 2016

LAP defects may lead to lupus-like autoimmune disorder

A casual observation about size differences in mice has led to the discovery that defects in a process for digesting dead cells called LC3-associated phagocytosis (LAP) may lead to a lupus-like autoimmune disorder. St. Jude Children's Research Hospital scientists led the research, which appears as an advance online publication today in the scientific journal Nature.

21 Apr 2016

High fructose consumption during pregnancy may increase risk factors for heart disease in children

The negative health effects of consuming large amounts of fructose could impact several generations, according to researchers at The University of Texas Medical Branch at Galveston.

21 Apr 2016

Medical Science News

Clinical study shows watercress extract inhibits carcinogen activation in cigarette smokers

Vegetable-based polyphenol enhances wound healing

Researchers reposition existing prazosin drug to combat glioblastoma

Testosterone may lead to greater heart attack risk in men than women

TNF-alpha protein involved in autoimmune diseases may also promote tissue healing

Caltech researchers map out pathways of neurons responsible for Parkinson's motor impairments

Gladstone scientists bioengineer micro-scale heart tissues from stem cells

Novel method could help analyze GWAS results for sporadic diseases

Low levels of 25-hydroxyvitamin D highly prevalent among children with type 1 diabetes

Scientists find interaction between amyloid and tau proteins that cause brain damage linked with AD

Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

MAILES study finds link between fatty diets and sleep

Non-invasive test to diagnose EoE could replace need for repeated endoscopy

Scientists aim to identify marker that could indicate aggressive basal cell skin cancer

BioTek Instruments, MilliporeSigma collaborate on integrated solution for long-term live cell experiments

Scientists identify genetic variants that may influence wellbeing, depression and neuroticism

Orthocell announces further validation of 'Cell Factory' concept for generation of bone, cartilage

Scientists evaluate phage-based therapy to battle antibiotic-resistant bacterial superbug infections

LAP defects may lead to lupus-like autoimmune disorder

High fructose consumption during pregnancy may increase risk factors for heart disease in children

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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