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Newly discovered player in epigenetic regulation closely linked to known cancer promoters

If genes form the body's blueprint, then the layer of epigenetics decides which parts of the plan get built. Unfortunately, many cancers hijack epigenetics to modulate the expression of genes, thus promoting cancer growth and survival.

19 Apr 2016

Researchers examine neuropsychological effect in ecstasy users

Researchers from the University of Liverpool have conducted a study examining the effect ecstasy has on different parts of the brain.

19 Apr 2016

Researchers identify biological pathway that explains why current asthma therapies fail in many cases

Asthma is an enormous public health problem that continues to grow larger, in part because scientists don't fully understand how it is caused. Existing therapies don't cure the disease and often don't even significantly alleviate the symptoms. Now, scientists from the Perelman School of Medicine at the University of Pennsylvania and Rutgers University have identified a biological pathway that potentially explains why current asthma therapies don't work well in many cases—and might be targeted to help those patients.

19 Apr 2016

Study shows women may face decreased kidney damage from ischemia reperfusion injury

After a kidney transplant, women may experience decreased kidney damage from ischemia reperfusion injury compared to men due to the impact of gender-specific hormones, suggests a new preclinical study and an analysis of patient data published online in the Journal of Clinical Investigation from researchers at the Perelman School of Medicine at the University of Pennsylvania.

19 Apr 2016

Penn researchers report results of CAR therapy trial in brain cancer patients

Immune cells engineered to seek out and attack a type of deadly brain cancer known as glioblastoma (GBM) were found to have an acceptable safety profile and successfully migrate to and infiltrate tumors, researchers from Penn Medicine and Harvard University reported at the AACR Annual Meeting 2016.

19 Apr 2016

Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

Cancer cells often devise ways to survive even in the presence of toxic chemotherapy. Now, a research team led by investigators at Beth Israel Deaconess Medical Center has found a way to attack a process that tumor cells use to escape the effects of standard cancer drugs. The discovery is published online today in the journal Nature Cell Biology.

19 Apr 2016

Transplanted human islets prevent hypoglycemic events in Type 1 diabetes patients

Northwestern Medicine researchers are co-investigators in a breakthrough clinical trial that found transplanted human islets prevent hypoglycemic events and provide excellent glycemic control for patients with Type 1 diabetes with severe hypoglycemia.

19 Apr 2016

Scientists discover new diagnostic marker for liver cancer

Scientists may have discovered a significant new diagnostic marker for liver cancer, according to a paper published in the April 18 online issue of Nature Cell Biology.

19 Apr 2016

New computer algorithm can better characterize functional context of genomic variations in cancer

Cancer is rarely the result of a single mutation in a single gene. Rather, tumors arise from the complex interplay between any number of mutually exclusive abnormal changes in the genome, the combinations of which can be unique to each individual patient.

19 Apr 2016

UNC scientists develop new optogenetic tool to study function of different proteins

Scientists at the University of North Carolina School of Medicine have developed a way to embed light-responsive switches into proteins so that researchers can use lasers to manipulate protein movement and activity within living cells and animals.

19 Apr 2016

Inhibiting adrenaline receptors reduces breast cancer brain metastases

While we look to invent new medicines to treat cancer, a parallel approach to repurpose existing medicines may be highly effective. Stress, mediated by adrenaline, has been suspected to promote cancer growth and this research study shows that by blocking adrenaline receptors in breast cancers, they are less successful in spreading to and growing in the brain.

19 Apr 2016

Study investigates usefulness of plasma levels as biomarker for AD

A Centre for Healthy Brain Ageing paper published in Current Alzheimer Research presents the first detailed study of the relationship between plasma levels of two amyloid beta peptides (Aβ1-40 and Aβ1-42), brain volumetrics (measures studying the size of brain, which shrinks with Alzheimer's disease) and cognitive performance in an investigation of the usefulness of plasma levels as a biomarker for Alzheimer's disease (AD).

19 Apr 2016

Therapies based on alpha defensins could help treat rheumatoid arthritis

Arthritis and other inflammatory conditions could be helped by new insights into how the immune response is switched off.

19 Apr 2016

High dietary saturated fat intake may lead to prostate cancer aggressiveness

Eating a diet higher in saturated fat, a type of fat found commonly in foods such as fatty beef and cheese, was linked to more aggressive prostate cancer, a study by University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators has found. The preliminary results were presented Monday, April 18 at the American Association for Cancer Research Annual Meeting in New Orleans.

19 Apr 2016

Animal study links female resilience to renal ischemia with protective effects of estrogen

Kidney transplantation outcomes are adversely affected by ischemia-reperfusion injury, which occurs as a result of blood flow restrictions during the reperfusion stage of transplant surgery.

19 Apr 2016

Researchers develop new method for identifying DNA mutations in single cancer cell

Researchers at The University of Texas MD Anderson Cancer Center have announced a new method for detecting DNA mutations in a single cancer cell versus current technology that analyzes millions of cells which they believe could have important applications for cancer diagnosis and treatment. The results are published in the April 18 online issue of Nature Methods.

19 Apr 2016

Specific intake levels of xanthohumol reduces obesity, cholesterol and elevated glucose

A recent study at Oregon State University has identified specific intake levels of xanthohumol, a natural flavonoid found in hops, that significantly improved some of the underlying markers of metabolic syndrome in laboratory animals and also reduced weight gain.

19 Apr 2016

Medical Science News

Newly discovered player in epigenetic regulation closely linked to known cancer promoters

Researchers examine neuropsychological effect in ecstasy users

Researchers identify biological pathway that explains why current asthma therapies fail in many cases

Study shows women may face decreased kidney damage from ischemia reperfusion injury

Penn researchers report results of CAR therapy trial in brain cancer patients

Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

Transplanted human islets prevent hypoglycemic events in Type 1 diabetes patients

Scientists discover new diagnostic marker for liver cancer

New computer algorithm can better characterize functional context of genomic variations in cancer

UNC scientists develop new optogenetic tool to study function of different proteins

Inhibiting adrenaline receptors reduces breast cancer brain metastases

Study investigates usefulness of plasma levels as biomarker for AD

Therapies based on alpha defensins could help treat rheumatoid arthritis

High dietary saturated fat intake may lead to prostate cancer aggressiveness

Animal study links female resilience to renal ischemia with protective effects of estrogen

Researchers develop new method for identifying DNA mutations in single cancer cell

Specific intake levels of xanthohumol reduces obesity, cholesterol and elevated glucose

Researchers devise method to stably internalize chemotherapy loaded microparticles into prostate cells

Oxidized mitochondrial nucleoids released from neutrophils may contribute to SLE pathogenesis

Researchers successfully use stem cells to promote nerve fibre regeneration after spinal cord injuries

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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