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Novel therapy takes rheumatoid arthritis treatment in mice to a new level

Rheumatoid arthritis is a condition that causes painful inflammation of several joints in the body. The joint capsule becomes swollen, and the disease can also destroy cartilage and bone as it progresses. Rheumatoid arthritis affects 0.5% to 1% of the world's population. Up to this point, doctors have used various drugs to slow or stop the progression of the disease.

7 Aug 2014

MIT researchers generate liver tumors in adult mice

Sequencing the genomes of tumor cells has revealed thousands of mutations associated with cancer. One way to discover the role of these mutations is to breed a strain of mice that carry the genetic flaw — but breeding such mice is an expensive, time-consuming process.

7 Aug 2014

Low levels of vitamin D may double dementia, Alzheimer's risks

In the largest study of its kind, researchers suggests that in older people, not getting enough vitamin D may double the risk of developing dementia and Alzheimer's disease. The study is published in the August 6, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Aug 2014

UCSF researchers identify novel molecular features within the developing human brain

UC San Francisco researchers have identified cells' unique features within the developing human brain, using the latest technologies for analyzing gene activity in individual cells, and have demonstrated that large-scale cell surveys can be done much more efficiently and cheaply than was previously thought possible.

7 Aug 2014

Research sheds light on how wounds heal

Research by a civil engineer from the University of Waterloo is helping shed light on the way wounds heal and may someday have implications for understanding how cancer spreads, as well as why certain birth defects occur.

7 Aug 2014

RSAM, Rettsyndrome.org renew commitment to defeat Rett syndrome

Rett Syndrome Association of Massachusetts and Rettsyndrome.org are thrilled to announce today their renewed commitment to work together to defeat Rett syndrome. A generous $150,000 donation from RSAM will support a Rettsyndrome.org approved grant to Dr. Michela Fagiolini's project at the Boston Children's Hospital: "Assessing NMDA receptor (NMDAr) modulators to ameliorate cortical regression in Rett syndrome".

7 Aug 2014

Findings show how galectin-1 protein plays key role in high grade malignant gliomas

Brain tumors fly under the radar of the body's defense forces by coating their cells with extra amounts of a specific protein, new research shows.

7 Aug 2014

Researchers take major step forward in developing real ALS treatments

A series of studies begun by Harvard Stem Cell Institute scientists eight years ago has lead to a report published today that may be a major step forward in the quest to develop real treatments for amyotrophic lateral sclerosis, ALS, or Lou Gehrig's disease.

7 Aug 2014

Researchers compare circadian fluctuations in tactile sense/two-point discrimination in different individuals

Many previous chronobiological studies have reported on detection of circadian fluctuation in performing simple motor tasks, fine skilled movement, and anaerobic exercise.

7 Aug 2014

Induced immunorejection may eliminate tumors post-cell transplantation

Recent studies have shown that transplanting induced pluripotent stem cell-derived neural stem cells (iPS-NSCs) can promote functional recovery after spinal cord injury in rodents and non-human primates. However, a serious drawback to the transplantation of iPS-NSCs is the potential for tumor growth, or tumorogenesis, post-transplantation.

7 Aug 2014

CSSi President Chris Trizna honored as one of PharmaVOICE 100

CSSi, the leader in patient recruitment solutions for the clinical research industry, announced today that President Chris Trizna has been honored as one of the PharmaVOICE 100, an annual list from PharmaVOICE magazine of the most inspiring people in the life-sciences industry.

6 Aug 2014

Penn physiologist receives Javits Neuroscience Investigator Award from NIH

Erika Holzbaur, PhD, a professor of Physiology in the Perelman School of Medicine at the University of Pennsylvania, has received the Javits Neuroscience Investigator Award from the National Institutes of Health.

6 Aug 2014

Comprehensive database collecting information about microRNAs, multiMiR

Your genes are blueprints for proteins, and molecules called microRNA can help to determine how often these genetic blueprints are manufactured into proteins. Researchers often ask what microRNA regulates a gene related to disease.

6 Aug 2014

Quantum Materials achieves 95% QY for Green Tetrapod Quantum Dots production

Quantum Materials Corp (OTCQB:QTMM) (QMC) today announced achieving a calculated 95% Quantum Yield (QY) for Green Tetrapod Quantum Dots (TQD) manufactured by QMC's proprietary automated mass-production system.

6 Aug 2014

Researchers identify genetic variants associated with severe skin reactions to antiepileptic drug

Researchers have identified genetic variants that are associated with severe adverse skin reactions to the antiepileptic drug phenytoin, according to a study in the August 6 issue of JAMA.

6 Aug 2014

Receipt of nutrition via feeding tube may be harmful for ICU patients

Among mechanically ventilated intensive care unit (ICU) patients, receipt of high-protein nutrition via a feeding tube enriched with immune-modulating nutrients (such as glutamine, omega-3 fatty acids, and antioxidants) vs standard high-protein nutrition did not result in a significant difference in the incidence of new complications and may be harmful, as suggested by an increased risk of death at 6 months, according to a study in the August 6 issue of JAMA.

6 Aug 2014

Prosthetic arm controlled by imagining different movements

This design hopes to identify the memory of movement in the amputee's brain to translate to an order allowing manipulation of the device.

6 Aug 2014

Oraya awarded NIH grant to study how gold nanoparticles can enhance Wet AMD treatment

Oraya Therapeutics, Inc. announced today that they have been awarded a $215,000 Small Business Technology Transfer Grant from the National Institutes of Health to investigate how Oraya Therapy, a low voltage stereotactic radiotherapy, and gold nanoparticles can further enhance the treatment of wet age-related macular degeneration (Wet AMD).

6 Aug 2014

Eating pistachios may reduce body's response to stresses among adults with diabetes

Among people with type 2 diabetes, eating pistachios may reduce the body's response to the stresses of everyday life, according to Penn State researchers.

6 Aug 2014

Study to understand how tissues break down with age

Scientists at Queen Mary University of London (QMUL) have identified differences in the proteins present in young and old tendons, in new research that could guide the development of treatments to stop tissue breakdown from occurring.

6 Aug 2014