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STING agonists developed to induce cellular death in B cell malignancies

In almost every mammalian cell, you will find the endoplasmic reticulum, a network of continuous membranes responsible for controlling metabolism as well as the folding, assembly and secretion of proteins.

11 Mar 2016

Researchers develop new process for synthesis of potent anti-cancer agents

A team led by Rice University synthetic organic chemist K.C. Nicolaou has developed a new process for the synthesis of a series of potent anti-cancer agents originally found in bacteria.

10 Mar 2016

Brown fat may help to keep blood sugar steady in adults

Australian scientists have shown that brown fat - a special type of fat that burns energy to produce heat - may also help to keep blood sugar steady in adults.

10 Mar 2016

Maternal bacterial infections affect fetal brain anatomy and cognitive functioning after birth

St. Jude Children's Research Hospital scientists have discovered how pieces of bacterial cell wall cross the placenta and enter developing neurons, altering fetal brain anatomy and cognitive functioning after birth. The study appears today in the scientific journal Cell Host & Microbe.

10 Mar 2016

CYP3A7 gene may over-activate metabolism, reduce effectiveness of cancer treatments

Some patients with breast cancer, lung cancer and leukaemia seem to fare poorly after treatment because of the effects of a particular gene, a new study finds.

10 Mar 2016

Scientists explore new treatment avenues to protect obese individuals from cardiovascular disease

Fatness is clearly linked to cardiovascular disease, but scientists want to find why the unhealthy pair tend to go hand-in-hand and how to break up their relationship.

10 Mar 2016

Specific gene mutation may significantly reduce risk of heart attack

People with a specific gene mutation have a 50 percent lower risk of suffering a heart attack. This is what an international team of researchers headed by the cardiologist Prof. Heribert Schunkert, Medical Director of the German Heart Center at the Technical University of Munich (TUM), discovered in a broad comparative study. If this gene were switched off with medications it could reduce the risk of coronary disease significantly.

10 Mar 2016

Scientists discover novel drug candidate to treat breast cancer, lung cancer and melanoma

Using a new approach, scientists at The Scripps Research Institute and collaborating institutions have discovered a novel drug candidate that could be used to treat certain types of breast cancer, lung cancer and melanoma.

10 Mar 2016

Advion introduces new proteins and peptides analysis system at ABRF 2016 Annual Meeting

Advion, Inc., a leading systems and consumables developer for the life sciences industry, announced during the ABRF 2016 Annual Meeting in Fort Lauderdale, Florida the introduction of a proteins and peptides analysis system, 'TIDES EXPRESS.

From Advion 10 Mar 2016

Scientists discover molecular switch that can burn off excess pounds

The number of overweight people is increasing worldwide -- and thus the risk of developing diabetes or cardiovascular disease.

10 Mar 2016

Gar genome helps identify genetic sequences shared by human disease genes and zebrafish

Led by Drs John Postlethwait and Ingo Braasch from the Institute of Neuroscience, University of Oregon, US, in collaboration with the Broad Institute, the study of the Spotted Gar (Lepisosteus oculatus) genome reveals that it is small and manageable. Furthermore, it lacks much shuffling and duplication that occurred in the 'main' fish ancestral line; it conserved its genome.

10 Mar 2016

Repetitive movements in slow-learning stages can help individuals retain motor skills

Researchers in Japan have found that repetitive movements in slow-learning stages can alter an area of the brain responsible for movement, and help individuals retain these motor skills.

10 Mar 2016

Is the global diet getting sweeter? An interview with Professor Barry Popkin

In the past, caloric sweeteners simply referred to cane sugar or beet sugar. However, over time we've created hundreds of different sugars that are all providing calories of the same amount, about four calories for every gram of the sugar. Some examples include corn syrups and more processed sweeteners like high fructose corn syrup.

10 Mar 2016

MDI Biological Laboratory discover mechanisms underlying regeneration of heart tissue

The MDI Biological Laboratory has announced new discoveries about the mechanisms underlying the regeneration of heart tissue by Assistant Professor Voot P. Yin, Ph.D., which raise hope that drugs can be identified to help the body grow muscle cells and remove scar tissue, important steps in the regeneration of heart tissue.

10 Mar 2016

Tailored new compound can dramatically reduce brain damage resulting from stroke

After suffering a stroke, about three-fourths of patients exhibit some disability. The extent of a patient's symptoms depends on the degree and location of brain tissue damage following the stroke event. This week in ACS Central Science, researchers show that by using a tailored small molecule to turn off the production of a key neuromodulator in the brain, they can dramatically reduce brain damage in stroke models in rats.

10 Mar 2016

Early childhood presents short-lived window for intervention to ensure future cardio-metabolic health

Research conducted at LSU Health New Orleans School of Public Health has found that exposure to poverty does not produce metabolic and inflammatory biomarkers in young, healthy children. It identifies early childhood as an opportunity to prevent a known association in adults between poverty and the metabolic syndrome. The study is one of the first to characterize the timing of exposure to such stress and the emergence of the physiologic changes leading to cardio-metabolic disease and to document these relationships during this critical developmental period.

10 Mar 2016

Bioengineers introduce CORDA algorithm to find new therapeutic targets for cancer

Rice University bioengineers have introduced a fast computational method to model tissue-specific metabolic pathways. Their algorithm may help researchers find new therapeutic targets for cancer and other diseases.

10 Mar 2016

Practicing movements at different speeds enhances certain nerve functions after stroke or spine injury

Changes in one circuit of nerves, but not another, in the spinal cord depend on how quickly muscles must move to complete a task, according to results from the Human Motor Control Laboratory of Professor Kozo Funase, PhD, at Hiroshima University. The results could influence physical therapy routines for patients struggling to control their bodies after a stroke or spine injury.

10 Mar 2016

New, regenerative medicine approach developed to remove congenital cataracts in infants

Researchers at University of California, San Diego School of Medicine and Shiley Eye Institute, with colleagues in China, have developed a new, regenerative medicine approach to remove congenital cataracts in infants, permitting remaining stem cells to regrow functional lenses.

10 Mar 2016

TSRI researchers uncover new molecular mechanism underlying neurodegenerative diseases

A new study led by scientists at The Scripps Research Institute suggests that cells construct protein "clumps" to protect against neurodegenerative diseases such as amyotrophic lateral sclerosis, a.k.a. ALS or Lou Gehrig's disease.

10 Mar 2016

Medical Science News

STING agonists developed to induce cellular death in B cell malignancies

Researchers develop new process for synthesis of potent anti-cancer agents

Brown fat may help to keep blood sugar steady in adults

Maternal bacterial infections affect fetal brain anatomy and cognitive functioning after birth

CYP3A7 gene may over-activate metabolism, reduce effectiveness of cancer treatments

Scientists explore new treatment avenues to protect obese individuals from cardiovascular disease

Specific gene mutation may significantly reduce risk of heart attack

Scientists discover novel drug candidate to treat breast cancer, lung cancer and melanoma

Advion introduces new proteins and peptides analysis system at ABRF 2016 Annual Meeting

Scientists discover molecular switch that can burn off excess pounds

Gar genome helps identify genetic sequences shared by human disease genes and zebrafish

Repetitive movements in slow-learning stages can help individuals retain motor skills

Is the global diet getting sweeter? An interview with Professor Barry Popkin

MDI Biological Laboratory discover mechanisms underlying regeneration of heart tissue

Tailored new compound can dramatically reduce brain damage resulting from stroke

Early childhood presents short-lived window for intervention to ensure future cardio-metabolic health

Bioengineers introduce CORDA algorithm to find new therapeutic targets for cancer

Practicing movements at different speeds enhances certain nerve functions after stroke or spine injury

New, regenerative medicine approach developed to remove congenital cataracts in infants

TSRI researchers uncover new molecular mechanism underlying neurodegenerative diseases

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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