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Blood test may spot first signs of skin cancer relapse

A BLOOD test may be able to sound early warning bells that patients with advanced melanoma skin cancer are relapsing, according to a study published in the journal Cancer Discovery today (Monday).

7 Mar 2016

Absence of PEMT enzyme leads to development of fatty liver disease and tumours in thin patients

Researchers observe protection against obesity and insulin resistance but at the cost of prominent fatty liver disease in mice lacking the PEMT enzyme and patients with low levels of PEMT.

7 Mar 2016

CTRC study provides new insight into how Angelina Jolie gene functions in normal breast tissue

Scientists from the Cancer Therapy & Research Center in San Antonio today (March 4) published work that provides deeper insight into how the Angelina Jolie gene, BRCA1, functions in normal breast tissue and how its loss results in breast cancer.

7 Mar 2016

Researchers develop new technique to create naïve pluripotent stem cells

Scientists at the University of Cambridge have for the first time shown that it is possible to derive from a human embryo so-called 'naïve' pluripotent stem cells - one of the most flexible types of stem cell, which can develop into all human tissue other than the placenta.

7 Mar 2016

First atomic-scale view of interaction between HIV capsid and host protein cyclophilin A

A new study offers the first atomic-scale view of an interaction between the HIV capsid - the protein coat that shepherds HIV into the nucleus of human cells - and a host protein known as cyclophilin A. This interaction is key to HIV infection, researchers say.

7 Mar 2016

Complex biomarker tests for molecularly targeted therapies lack evidentiary standards

Potentially useful biomarker tests for molecularly targeted therapies are not being adopted appropriately into clinical practice because of a lack of common evidentiary standards necessary for regulatory, reimbursement, and treatment decisions.

7 Mar 2016

Research highlights association of western diet with Alzheimer's disease

Recent research has established associations between certain environmental factors, including eating a western diet and being sedentary, with an increased susceptibility to Alzheimer's disease. In fact, it is estimated that a combination of diet and inactivity contributes to as many as 25% of Alzheimer's cases. Nonetheless, little is known about the exact disease mechanisms and how or why this increasingly common middle-age lifestyle can play such a big role in subsequent cognitive function.

7 Mar 2016

Researchers solve structure of key protein in coronaviruses, like MERS and SARS

When the respiratory illness SARS (Severe Acute Respiratory Syndrome) emerged in 2003, it killed at least 775 people before it was contained. Nine years later, MERS (Middle East Respiratory Syndrome) began circulating in the human population—and has gone on to have a 36 percent case fatality rate.

7 Mar 2016

Leukemia researchers uncover protein that allows blood cancers to develop

Walter and Eliza Hall Institute researchers have uncovered a protein that is key to the development of blood cancers caused by a common genetic error.

7 Mar 2016

Kessler Foundation's Silvana L. Costa awarded Switzer Research Fellowship for research on MS

Silvana L. Costa, PhD, of Kessler Foundation has been awarded a Switzer Research Fellowship by the National Institute on Disability, Independent Living and Rehabilitation Research. The $70,000 Merit Award funds her research on "Processing Speed Deficits in Multiple Sclerosis: Exploring the Complex Sensorial Cognitive Motor Interaction."

7 Mar 2016

Expression of BIRC3 protein associated with poor survival, recurrent disease in GBM patients

Glioblastoma multiforme (GBM) is a highly aggressive brain tumor with low survival rates, with newly diagnosed patients surviving a median of 14 months and recurrent patients surviving a median of only 3 to 9 months. New therapeutic targets and biomarkers for prognosis are urgently needed.

7 Mar 2016

Researchers identify how Zika virus may cause microcephaly in fetuses

Working with lab-grown human stem cells, a team of researchers suspect they have discovered how the Zika virus probably causes microcephaly in fetuses. The virus selectively infects cells that form the brain's cortex, or outer layer, making them more likely to die and less likely to divide normally and make new brain cells.

7 Mar 2016

FSU researchers make major breakthrough in Zika virus research

Florida State University researchers have made a major breakthrough in the quest to learn whether the Zika virus is linked to birth defects with the discovery that the virus is directly targeting brain development cells and stunting their growth.

7 Mar 2016

Athletes carrying specific genotype at greater risk of prolonged recovery following concussion

Genetic research on concussions is progressing in many different avenues. However, researchers presenting their work at the American Orthopaedic Society for Sports Medicine's Specialty Day, believe there may be a new genetic connection regarding recovery rates following a sports-related concussion.

7 Mar 2016

Long-term exercise may benefit Spinal Muscular Atrophy patients

Long-term exercise appears to be beneficial for Spinal Muscular Atrophy (SMA) like mice, suggesting a potential of active physiotherapy for patient care; according to a study published today in the Journal of Physiology.

6 Mar 2016

Antibiotic resistance: A serious threat to human health

The World Health Organization has identified antibiotic resistance as a serious threat to human health across the world. The Journal of Environmental Quality recently published a special section titled "Antibiotics in Agroecosystems" to address the science of this important topic.

4 Mar 2016

Allen Institute, Blue Brain Project collaborate to develop simulation-based tools to study neurons

The Allen Institute for Brain Science and the Blue Brain Project are deepening their collaboration. Today, the US-based Allen Institute is releasing a set of 40 computer models of neurons from the mouse visual cortex, created using tools developed by the Swiss-based Blue Brain Project at EPFL. Using Blue Brain technology, the researchers were able to reproduce the physiology and electrical activity of the neurons with an extremely high level of detail.

4 Mar 2016

IOM report elucidates state of ovarian cancer incidence, treatment and research

Ovarian cancer, one of the deadliest malignancies, is actually a constellation of different cancers that may originate in other organs and should not be treated as a single disease, concludes a new congressionally mandated report on the state of ovarian cancer incidence, treatment and research. The report, published by the Institute of Medicine of the National Academies of Sciences, Engineering, and Medicine, also highlights persistent serious disparities in delivery of care across different groups of women in the U.S., and suggests promising areas for further research.

4 Mar 2016

Routine stress adversely affects women’s heart

While the number of men dying from a heart attack has been constantly decreasing during the past twenty years, the fatal risk particularly in young women has increased significantly. Gender medicine has already demonstrated that women exhibit different symptoms. A new insight shows that stress in the daily routine has particularly adverse effects on the hearts of women. This was emphasised by Alexandra Kautzky-Willer, Professor for Gender Medicine of MedUni Vienna, on the occasion of the impending International Women's Day on 8 March 2016.

4 Mar 2016

Research highlights how the brain handles numbers

Small numbers are processed in the right side of the brain, while large numbers are processed in the left side of the brain, new research suggests.

4 Mar 2016

Medical Science News

Blood test may spot first signs of skin cancer relapse

Absence of PEMT enzyme leads to development of fatty liver disease and tumours in thin patients

CTRC study provides new insight into how Angelina Jolie gene functions in normal breast tissue

Researchers develop new technique to create naïve pluripotent stem cells

First atomic-scale view of interaction between HIV capsid and host protein cyclophilin A

Complex biomarker tests for molecularly targeted therapies lack evidentiary standards

Research highlights association of western diet with Alzheimer's disease

Researchers solve structure of key protein in coronaviruses, like MERS and SARS

Leukemia researchers uncover protein that allows blood cancers to develop

Kessler Foundation's Silvana L. Costa awarded Switzer Research Fellowship for research on MS

Expression of BIRC3 protein associated with poor survival, recurrent disease in GBM patients

Researchers identify how Zika virus may cause microcephaly in fetuses

FSU researchers make major breakthrough in Zika virus research

Athletes carrying specific genotype at greater risk of prolonged recovery following concussion

Long-term exercise may benefit Spinal Muscular Atrophy patients

Antibiotic resistance: A serious threat to human health

Allen Institute, Blue Brain Project collaborate to develop simulation-based tools to study neurons

IOM report elucidates state of ovarian cancer incidence, treatment and research

Routine stress adversely affects women’s heart

Research highlights how the brain handles numbers

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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