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$Multidisciplinary experts assess effects of osteoporosis drugs on fracture healing$

Multidisciplinary experts assess effects of osteoporosis drugs on fracture healing

In people with osteoporosis, one fracture often leads to more fractures, and potentially a future of pain, disability, and poor quality of life. While studies have shown that such high-risk patients benefit from appropriate medication to reduce future fracture risk, more research is needed on the effect of osteoporosis medications on fracture healing.

28 Apr 2016

Certain genetic markers linked with depression can also predict who may benefit from exercise

Call it personalized medicine for depression -- but the prescription in this case is exercise, which University of Florida Health researchers have found helps people with certain genetic traits.

28 Apr 2016

Scientists build semantic atlas to show how human brain organizes language

What if a map of the brain could help us decode people's inner thoughts? Scientists at the University of California, Berkeley, have taken a step in that direction by building a "semantic atlas" that shows in vivid colors and multiple dimensions how the human brain organizes language. The atlas identifies brain areas that respond to words that have similar meanings.

28 Apr 2016

Patients with impaired consciousness show uncontrolled communication between resting-state networks

An international research team has investigated interactions in different states of consciousness and has discovered that patients with severely impaired consciousness show a pathological or uncontrolled communication between resting-state networks.

28 Apr 2016

Group of gamma-protocadherins linked with neurons help regulate growth of dendrites

When you think of a neuron, imagine a tree. A healthy brain cell indeed looks like a tree with a full canopy. There's a trunk, which is the cell's nucleus; there's a root system, embodied in a single axon; and there are the branches, called dendrites.

28 Apr 2016

Scientists show how HIV enters female reproductive tract

Finding the vulnerable points where HIV enters the female reproductive tract is like searching for needles in a haystack. But Northwestern Medicine scientists have solved that challenge by creating a glowing map of the very first cells to be infected with a HIV-like virus.

28 Apr 2016

Bonn researchers identify new technique to measure activity of brown fat cells

Brown fat cells can burn fat to generate heat. University of Bonn researchers have discovered a new method to measure the activity of brown fat cells in humans and mice. The researchers showed that microRNA-92a can be used as an indirect measure for the activity of energy consuming brown fat cells. They showed that a small blood sample was sufficient. Results were published in "Nature Communications," a well-known scientific journal.

27 Apr 2016

Study reveals surprising results that may impair future therapeutic approaches in TGF-beta pathway

Researchers at Helmholtz Zentrum München describe how breast cancer cells challenged with a small-molecule inhibitor targeting specific invasive properties switch to an alternative mode-of-action, rendering them even more aggressive. The results may impair future therapeutic approaches in the TGF-beta pathway and are published in the journal 'Oncotarget'.

27 Apr 2016

People's ability to smell declines with age

You not only pick up aromas through your nose, but also through your mouth while you chew your food. Some people simply can smell better than others and those may enjoy an enhanced flavor of foods. Unfortunately, for some, this ability decreases with age, report Tyler Flaherty and Juyun Lim of Oregon State University in the US in Springer's journal Chemosensory Perception.

27 Apr 2016

Clinical study to evaluate safety of investigational cell therapy to treat chronic motor deficits after stroke

University Hospitals Case Medical Center is the first surgical site for a Phase 2b clinical trial study to further evaluate the safety and efficacy of an investigational cell therapy for the treatment of chronic motor deficit following an ischemic stroke.

27 Apr 2016

New study on retroviral DNA could help improve treatments for HIV infection

When retroviruses such as HIV infect a cell, they first make a copy of their RNA genome in the form of DNA. The relatively short viral DNA strand then moves to the cell nucleus, where it inserts itself into the host cell's DNA.

27 Apr 2016

TSRI study reveals important traits in LCMV, Lassa virus

For the first time, scientists at The Scripps Research Institute (TSRI) have solved the structure of the biological machinery used by a common virus to recognize and attack human host cells.

27 Apr 2016

Modernization of screening methods in sperm banks could protect future children from highly heritable diseases

U.S. sperm banks perform genetic testing to screen for and disqualify carriers of a limited number of recessive disease mutations, but more comprehensive and affordable DNA-based screening methods are now available that can detect many more disease-causing genetic variations.

27 Apr 2016

Exposure to titanium dioxide nanoparticles increases bacterial infection of HeLa cells

When human cells are exposed to titanium dioxide without the presence of UV light from the sun, the risk for bacterial infection more than doubles. This finding by a Stony Brook University-led research team, published early online in the Journal of Nanobiotechnology, raises concerns about exposure to titanium dioxide, a nanoparticle commonly used in millions of products worldwide ranging from cosmetics to toothpaste, gum, food coloring, and medicines.

27 Apr 2016

New rat study shows specific genetic factors may contribute to differences in addiction among humans

Why does one person who tries cocaine get addicted, while another might use it and then leave it alone? Why do some people who kick a drug habit manage to stay clean, while others relapse? And why do some families seem more prone to addiction than others?

27 Apr 2016

Rapamycin drug could target neural damage linked to Leigh syndrome

Salk Institute scientists showed how an FDA-approved drug boosts the health of brain cells by limiting their energy use. Like removing unnecessary lighting from a financially strapped household to save on electricity bills, the drug--called rapamycin--prolongs the survival of diseased neurons by forcing them to reduce protein production to conserve cellular energy.

27 Apr 2016

TGen scientists trace likely origins, dispersal of fungus that causes Valley Fever

Using the latest in genomic analysis technologies, scientists at the Translational Genomics Research Institute have tracked the likely origins and dispersal of the fungus that causes Valley Fever, according to a study published today in the journal mBio, the premiere journal for reporting high impact microbiological research.

27 Apr 2016

UNC-Chapel Hill researchers identify functional brain circuit that controls alcohol binge drinking

Researchers at the University of North Carolina at Chapel Hill have identified a circuit between two brain regions that controls alcohol binge drinking, offering a more complete picture on what drives a behavior that costs the United States more than $170 billion annually and how it can be treated.

27 Apr 2016

Study reveals new function for CACNA1C gene in psychiatric diseases

A new study shows the death of newborn brain cells may be linked to a genetic risk factor for five major psychiatric diseases, and at the same time shows a compound currently being developed for use in humans may have therapeutic value for these diseases by preventing the cells from dying.

27 Apr 2016

Review focuses on autologous cell therapy that can be applied to cardiac surgery

The combination of cell and gene therapy is rapidly raising clinical interest, although their combination has been under investigation for several decades. This is mainly due to the availability and feasibility of clinically relevant gene delivery options. This review focuses on cell therapies for heart failure and their use combined with cardiac surgery as well as with gene therapy.

27 Apr 2016

Medical Science News

Multidisciplinary experts assess effects of osteoporosis drugs on fracture healing

Certain genetic markers linked with depression can also predict who may benefit from exercise

Scientists build semantic atlas to show how human brain organizes language

Patients with impaired consciousness show uncontrolled communication between resting-state networks

Group of gamma-protocadherins linked with neurons help regulate growth of dendrites

Scientists show how HIV enters female reproductive tract

Bonn researchers identify new technique to measure activity of brown fat cells

Study reveals surprising results that may impair future therapeutic approaches in TGF-beta pathway

People's ability to smell declines with age

Clinical study to evaluate safety of investigational cell therapy to treat chronic motor deficits after stroke

New study on retroviral DNA could help improve treatments for HIV infection

TSRI study reveals important traits in LCMV, Lassa virus

Modernization of screening methods in sperm banks could protect future children from highly heritable diseases

Exposure to titanium dioxide nanoparticles increases bacterial infection of HeLa cells

New rat study shows specific genetic factors may contribute to differences in addiction among humans

Rapamycin drug could target neural damage linked to Leigh syndrome

TGen scientists trace likely origins, dispersal of fungus that causes Valley Fever

UNC-Chapel Hill researchers identify functional brain circuit that controls alcohol binge drinking

Study reveals new function for CACNA1C gene in psychiatric diseases

Review focuses on autologous cell therapy that can be applied to cardiac surgery

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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