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CUMC's Laboratory of Personalized Genomic Medicine granted approval for Columbia Combined Cancer Panel

The Laboratory of Personalized Genomic Medicine at Columbia University Medical Center has been granted full approval by the New York State Department of Health for the Columbia Combined Cancer Panel, (CCCP). This panel queries 467 cancer-related genes and was designed in collaboration with Columbia University Medical Center oncologists.

25 Sep 2015

Fungi research may lead to cheaper anti-cancer drugs for humans

Cheaper anti-cancer drugs for humans might ultimately stem from a new study by University of Guelph scientists into a kind of microbial "bandage" that protects yew trees from disease-causing fungi.

25 Sep 2015

Matchmaker Exchange platform launched for uncovering rare disease genes

In a special issue of Human Mutation, a team including investigators at Brigham and Women's Hospital has announced the launch of the Matchmaker Exchange - a way for the rare disease community to share information and find new connections. Matchmaker Exchange connects databases of genetic information and symptoms that physicians and investigators can "match" with a patient's rare disease.

25 Sep 2015

DNA nanostructures provide novel applications in molecular medicine

Researchers from Aalto University have published an article in the recent Trends in Biotechnology journal. The article discusses how DNA molecules can be assembled into tailored and complex nanostructures, and further, how these structures can find uses in therapeutics and bionanotechnological applications.

25 Sep 2015

Medication used for diabetes could be a valuable tool for treating alcohol dependence

A new study on mice and rats at Sahlgrenska Academy shows that a medication used for diabetes and obesity also could be a valuable tool for the treatment of alcohol dependence.

25 Sep 2015

UCSF researchers develop molecular 'on switch' that allows control over the actions of T cells

UC San Francisco researchers have engineered a molecular "on switch" that allows tight control over the actions of T cells, immune system cells that have shown great potential as therapies for cancer. The innovation lays the groundwork for sharply reducing severe, sometimes deadly side effects that have been a significant hurdle to advancing T cell-based treatments.

25 Sep 2015

Research highlights potential new treatment strategy for degenerative diseases

St. Jude Children's Research Hospital scientists have discovered evidence of a mechanism at the heart of amyotrophic lateral sclerosis (ALS) and related degenerative diseases. The research appears in today's edition of the journal Cell and highlights a possible new treatment strategy for the devastating disorders.

25 Sep 2015

HIV cure research may shift from single-therapy development model to combination therapy trials

The next five years of HIV research should shift gears from the classic single-therapy development model to moving directly from in vitro studies to combination therapy trials, authors argue in a new paper published online today.

25 Sep 2015

HSCI researchers find surprising similarities between SMA and ALS

Harvard Stem Cell Institute researchers studying spinal muscular atrophy (SMA) have found what they term "surprising similarities" between this childhood disorder that attacks motor neurons and amyotrophic lateral sclerosis (ALS), more commonly known as Lou Gehrig's disease.

25 Sep 2015

Sticky, protein-rich gel improves cardiac function after simulated heart attacks

A sticky, protein-rich gel created by Johns Hopkins researchers appears to help stem cells stay on or in rat hearts and restore their metabolism after transplantation, improving cardiac function after simulated heart attacks, according to results of a new study.

25 Sep 2015

Brain & Behavior Research Foundation announces recipients of NARSAD Young Investigator Grants

The Brain & Behavior Research Foundation today announced the award of its NARSAD Young Investigator Grants valued at more than $13 million to 191 of the world's most promising young scientists.

24 Sep 2015

Protein-coding gene identified as tumor suppressor for acute myeloid leukemia

A protein-coding gene called hnRNP K has been identified as a tumor suppressor for acute myeloid leukemia (AML), a finding that could be important for investigating how best to target treatment of a blood cancer striking mostly older individuals.

24 Sep 2015

Study compares general and domain-specific measures of self-control to predict consumer behavior

You can resist buying a candy bar while you're waiting in the checkout line at the grocery store--but you'll buy any pair of shoes that are on sale. Your best friend, in contrast, wouldn't dream of buying a pair of shoes he thinks he doesn't need, no matter how low the price--but he can't resist buying that same candy bar you so easily ignore.

24 Sep 2015

Researchers reveal potential new treatment methods for fatal brain disease

Researchers from the University of Zurich and the University Hospital Zurich reveal possible new treatment methods for a rare, usually fatal brain disease. Thanks to their discovery that specific antibodies play a key role in combating the viral infection, a vaccine against the disease "progressive multifocal leukoencephalopathy" could now be developed.

24 Sep 2015

New technique allows scientists to see blood-forming stem cells present in the bone marrow

A team of scientists at the Children's Research Institute at UT Southwestern has become the first to use a tissue-clearing technique to localize a rare stem cell population, in the process cracking open a black box containing detailed information about where blood-forming stem cells are located and how they are maintained.

24 Sep 2015

Discovery opens door to more targeted, effective treatments for cancer

In a discovery that could lead to more targeted and effective treatments for certain lung and prostate cancers, researchers at the University of Virginia School of Medicine have identified two new cancer-causing gene mutations - mutations that may be particularly susceptible to cancer-fighting drugs already approved by the federal Food and Drug Administration. One of the gene mutations also may play a key role in early menopause.

24 Sep 2015

Neuroscientists reveal the brain malady responsible for tinnitus, chronic pain

Neuroscientists at Georgetown University Medical Center and Germany's Technische Universität München say they've uncovered the brain malady responsible for tinnitus and for chronic pain — the uncomfortable, sometimes agonizing sensations that persist long after an initial injury.

24 Sep 2015

Research suggests potential drug targets to stop cancer spread

It only takes seconds: one cancerous cell breaks off from a tumor, slips into the bloodstream and quickly lodges elsewhere in the body. These colonizers may bloom into deadly metastatic cancer right away or lie dormant for years, only to trigger a recurrence decades after the primary tumor is removed.

24 Sep 2015

Stanford researchers successfully defeat C. difficile bacteria

Stanford University School of Medicine scientists successfully defeated a dangerous intestinal pathogen, Clostridium difficile, with a drug targeting its toxins rather than its life.

24 Sep 2015

Novel approach promises easier way to detect protein fibers implicated in neuro-degenerative diseases

Liquid crystals are familiar to most of us as the somewhat humdrum stuff used to make computer displays and TVs. Even for scientists, it has not been easy to find other ways of using them.

24 Sep 2015

Medical Science News

CUMC's Laboratory of Personalized Genomic Medicine granted approval for Columbia Combined Cancer Panel

Fungi research may lead to cheaper anti-cancer drugs for humans

Matchmaker Exchange platform launched for uncovering rare disease genes

DNA nanostructures provide novel applications in molecular medicine

Medication used for diabetes could be a valuable tool for treating alcohol dependence

UCSF researchers develop molecular 'on switch' that allows control over the actions of T cells

Research highlights potential new treatment strategy for degenerative diseases

HIV cure research may shift from single-therapy development model to combination therapy trials

HSCI researchers find surprising similarities between SMA and ALS

Sticky, protein-rich gel improves cardiac function after simulated heart attacks

Brain & Behavior Research Foundation announces recipients of NARSAD Young Investigator Grants

Protein-coding gene identified as tumor suppressor for acute myeloid leukemia

Study compares general and domain-specific measures of self-control to predict consumer behavior

Researchers reveal potential new treatment methods for fatal brain disease

New technique allows scientists to see blood-forming stem cells present in the bone marrow

Discovery opens door to more targeted, effective treatments for cancer

Neuroscientists reveal the brain malady responsible for tinnitus, chronic pain

Research suggests potential drug targets to stop cancer spread

Stanford researchers successfully defeat C. difficile bacteria

Novel approach promises easier way to detect protein fibers implicated in neuro-degenerative diseases

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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