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Long-term sulfonylurea use linked to increased risk of hypoglycemia unawareness

Sulfonylureas are a class of oral medications used to manage blood glucose levels in patients with type 2 diabetes.

22 Jul 2024

Study: Danger circuit relies on neuropeptides, not neurotransmitters

In the split second as you accidentally touch the hot handle of a cast iron skillet, pain and a sense of danger rush in.

22 Jul 2024

USC scientists transform B cells into cancer and HIV destroyers

USC scientists have discovered a way to turn the body's B cells into tiny surveillance machines and antibody factories that can pump out specially designed antibodies to destroy cancer cells or HIV, two of medicine's most formidable foes.

22 Jul 2024

Synthetic solutions for ethical and effective drug testing

Improving human quality of life with drug treatments is a complicated issue. Drug certification, including drug safety and reliability, entails a long series of tests and government approvals before the drug is available for anyone to use.

22 Jul 2024

Innovative genetic approaches to rare disease diagnosis

The majority of rare diseases have a genetic cause. The underlying genetic alteration can be found more and more easily, for example by means of exome sequencing (ES), leading to a molecular genetic diagnosis.

22 Jul 2024

New combined cell therapy for kidney transplants can help reduce donor-specific immune response

A new combined cell therapy for kidney transplants can help to reduce the donor-specific reaction against the transplanted organ without the need for maintenance triple immunosuppression.

22 Jul 2024

Brain coupling patterns as predictive markers for psychosis in 22q11.2DS

A UNIGE team shows that overly strong or weak interconnections between certain brain areas could be a predictive marker of the disease.

22 Jul 2024

Duke-NUS unveils LIVE Ventures to catalyze the commercialization of academic research

Duke-NUS Medical School today launched LIVE Ventures, a S$20 million incubation programme designed to catalyse the commercialisation of innovative academic research.

22 Jul 2024

Women with endometriosis have a significantly increased ovarian cancer risk, study finds

Researchers from the United States of America investigated the potential association between different subtypes of endometriosis and the incidence of ovarian cancer.

22 Jul 2024

Why do we blush, and what are the underlying mechanisms of blushing? Research aims to find out

Researchers investigated the neural substrates and mental processes underlying blushing in response to self-observation.

22 Jul 2024

Living near greenspace in midlife tied to slower cognitive decline in older age

The association between midlife residential greenness and cognitive decline.

22 Jul 2024

How music lessons can shape children's social and emotional growth

Long-term music instruction improves children's pitch-matching skills and certain socioemotional abilities, with the strongest benefits observed in music-related tasks.

21 Jul 2024

Breakthrough malaria vaccines RTS,S and R21 poised to save thousands of lives

Research paper reviews the efficacy of the first licensed malaria vaccines, RTS,S and R21, highlighting their potential to significantly reduce childhood mortality and discussing future vaccine development strategies.

21 Jul 2024

Long-term immune changes persist in unvaccinated COVID-19 patients

Study reveals that unvaccinated individuals experience significant long-term changes in immune parameters up to ten months post-COVID-19 infection, with a shift towards a Th2 cytokine profile.

21 Jul 2024

Saffron: A golden remedy for modern health challenges

Review highlights saffron's potential in preventing and treating various human diseases through its bioactive compounds. Clinical and preclinical studies confirm saffron's benefits in conditions like maculopathy, depression, neurodegenerative diseases, and cancer.

21 Jul 2024

Concussions in retired rugby players linked to higher neurodegenerative disease biomarkers

A study in the International Journal of Molecular Sciences reveals that retired rugby players with a history of concussions exhibit significant differences in biomarkers associated with neurodegenerative diseases compared to non-contact sports participants.

21 Jul 2024

Ultra-processed food consumption trends among UK adolescents show regional and socioeconomic disparities

A study in the European Journal of Nutrition reveals that UK adolescents' ultra-processed food consumption varies by age, ethnicity, and socioeconomic status, with significant differences across regions.

21 Jul 2024

AI and imaging advances revolutionize multiple sclerosis diagnosis

A study in Translational Vision Science & Technology reveals that integrating AI with IR-SLO and OCT imaging improves the automated diagnosis and classification of multiple sclerosis.

21 Jul 2024

COVID pandemic boosted food diversity and diet quality in U.S. households, study finds

The COVID-19 pandemic led to temporary increases in food diversity and diet quality in U.S. households, with notable improvements in household food purchasing behavior.

21 Jul 2024

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, according to a preclinical study from investigators at the University of Pennsylvania's Perelman School of Medicine and Abramson Cancer Center.

19 Jul 2024