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IQWiG dossier assessment finds added benefit of afatinib in patients with certain mutations

Afatinib (trade name: Giotrif) has been approved since September 2013 for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with activating EGF receptor mutations who have not been treated with an EGF receptor tyrosine-kinase inhibitor (EGFR TKI).

21 Aug 2015

UC Davis researchers reveal how four proteins come together to help assemble tubulin

When they think about how cells put together the molecules that make life work, biologists have tended to think of assembly lines: Add A to B, tack on C, and so on. But the reality might be more like a molecular version of a 3-D printer, where a single mechanism assembles the molecule in one go.

21 Aug 2015

Study sheds light on helper cells and killer cells

Scientists at the University of Bonn, together with colleagues from the USA and Japan, have shed light on an important immune mechanism. Their work shows how the body provides the important killer cells with a helper in the case of an infection. The study could point the way to better vaccines in the future.

21 Aug 2015

Researchers evaluate use of human fetal progenitor tenocyte to repair tendon injuries

Tendon injuries, especially those acquired while engaging in sports, are not easily healed due to the fibrous nature of tendon tissues which transmit forces from muscle to bone and protect surrounding tissues against tension and compression. Tendon injuries to wrists, knees, elbows and rotator cuffs, often from over use when playing golf or tennis, are increasingly common for both professional and amateur athletes ("weekend warriors") alike.

21 Aug 2015

Novel synthetic DNA vaccine induces protective immunity against MERS virus in animal study

A novel synthetic DNA vaccine can, for the first time, induce protective immunity against the Middle East Respiratory Syndrome (MERS) coronavirus in animal species, reported researchers from the Perelman School of Medicine at the University of Pennsylvania.

21 Aug 2015

New set of genes can indicate improved survival after surgery for pancreatic cancer patients

A study by the Translational Genomics Research Institute and other major research institutes, found a new set of genes that can indicate improved survival after surgery for patients with pancreatic cancer. The study also showed that detection of circulating tumor DNA in the blood could provide an early indication of tumor recurrence.

21 Aug 2015

Two proteins that help cells eliminate trash may contribute to development of Parkinson's disease

Two proteins that share the ability to help cells deal with their trash appear to need each other to do their jobs and when they don't connect, it appears to contribute to development of Parkinson's disease, scientists report.

21 Aug 2015

Researchers identify strategy to prevent adenoviruses from multiplying and causing sickness in humans

Using an animal model they developed, Saint Louis University and Utah State university researchers have identified a strategy that could keep a common group of viruses called adenoviruses from replicating and causing sickness in humans.

21 Aug 2015

Trojan horse strategy may elucidate why antibiotics ineffective in some patients

Bacteria are pretty wily creatures. Take for example, an organism such as Salmonella, which which are killed by antibiotics in lab tests, but can become highly resistant in the body.

21 Aug 2015

Researchers establish structure of important tumor-suppressing protein

An international group of researchers led by Carnegie Mellon University physicists Mathias Lösche and Frank Heinrich have established the structure of an important tumor suppressing protein, PTEN. Their findings provide new insights into how the protein regulates cell growth and how mutations in the gene that encodes the protein can lead to cancer.

21 Aug 2015

Hippocampus in the brain's temporal lobe involved in quick, successful conflict resolution

The hippocampus in the brain's temporal lobe is responsible for more than just long-term memory. Researchers have for the first time demonstrated that it is also involved in quick and successful conflict resolution.

21 Aug 2015

Potential biomarker could help prevent pre-diabetic individuals from developing Type II diabetes

Virginia Tech researchers have identified a biomarker in pre-diabetic individuals that could help prevent them from developing Type II diabetes.

21 Aug 2015

Johns Hopkins study advances scientific understanding of how DNA segments move among bacteria

Scientists at Johns Hopkins report they have deciphered the structure and unusual shape of a bacterial protein that prepares segments of DNA for the insertion of so-called jumping genes.

21 Aug 2015

Temporary postnatal visual deprivation induces permanent auditory responses in the brain's visual area

A brief period of postnatal visual deprivation, when early in life, drives a rewiring of the brain areas involved in visual processing, even if the visual restoration is completed well before the baby reaches one year of age, researchers at the University of Trento, McMaster University, and the University of Montreal revealed today in Current Biology.

21 Aug 2015

No single genetic strain associated with the worst cases of C. difficile infections

No single genetic strain of the widespread Clostridium difficile (C. difficile) bacteria appears to be any more harmful than other strains, according to new research published online today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

21 Aug 2015

NYBC, UC Davis Health System partner to manufacture potential stem cell therapies

New York Blood Center today announced a new collaboration with the University of California, Davis, Health System to manufacture specialized lines of stem cells as potential therapies for repair and regeneration of retina, kidney, lung and liver tissue, as well as for the treatment of neurodegenerative disorders such as Parkinson's, Alzheimer's and Huntington's disease.

20 Aug 2015

Tiny nanocrystals could be used in advanced medical imaging technologies to light up cancer cells

Researchers in China have developed tiny nanocrystals that could be used in the next generation of medical imaging technologies to light up cancer cells.

20 Aug 2015

AbVitro launches PairMe Grant Challenge to provide access to AbPair technology

AbVitro Inc., an immuno-oncology discovery company, today announced access to its AbPairTM technology by launching the "PairMe Grant Challenge."

20 Aug 2015

$IUPUI researcher receives NIH grant to study role of collagen in bone fracture resistance$

IUPUI researcher receives NIH grant to study role of collagen in bone fracture resistance

A biomedical engineer researcher at Indiana University-Purdue University Indianapolis has received a $419,000 National Institutes of Health grant to uncover why mechanical loading of bones increases their resistance to fractures.

20 Aug 2015

GMP protein can improve gastrointestinal health by protecting digestive system from pathogens

The protein glycomacropeptide (GMP) is derived from whey, the liquid by-product of the cheese-making process. GMP contains low amounts of the amino acid phenylalanine. Individuals who suffer from phenylketonuria—a metabolic disorder that causes cognitive impairment when phenylalanine level is too high—can use GMP as an alternative protein source. GMP supplementation has also been observed to improve gastrointestinal health by protecting the digestive system from pathogens and by having an anti-inflammatory effect.

20 Aug 2015

Medical Science News

IQWiG dossier assessment finds added benefit of afatinib in patients with certain mutations

UC Davis researchers reveal how four proteins come together to help assemble tubulin

Study sheds light on helper cells and killer cells

Researchers evaluate use of human fetal progenitor tenocyte to repair tendon injuries

Novel synthetic DNA vaccine induces protective immunity against MERS virus in animal study

New set of genes can indicate improved survival after surgery for pancreatic cancer patients

Two proteins that help cells eliminate trash may contribute to development of Parkinson's disease

Researchers identify strategy to prevent adenoviruses from multiplying and causing sickness in humans

Trojan horse strategy may elucidate why antibiotics ineffective in some patients

Researchers establish structure of important tumor-suppressing protein

Hippocampus in the brain's temporal lobe involved in quick, successful conflict resolution

Potential biomarker could help prevent pre-diabetic individuals from developing Type II diabetes

Johns Hopkins study advances scientific understanding of how DNA segments move among bacteria

Temporary postnatal visual deprivation induces permanent auditory responses in the brain's visual area

No single genetic strain associated with the worst cases of C. difficile infections

NYBC, UC Davis Health System partner to manufacture potential stem cell therapies

Tiny nanocrystals could be used in advanced medical imaging technologies to light up cancer cells

AbVitro launches PairMe Grant Challenge to provide access to AbPair technology

IUPUI researcher receives NIH grant to study role of collagen in bone fracture resistance

GMP protein can improve gastrointestinal health by protecting digestive system from pathogens

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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