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Antivirulence antibiotics could evade resistance longer than traditional antibiotics

We've all seen the headlines. "Man found to be shedding virulent strain of polio"; "Virulent flu strain in Europe hits the economy"; "Most virulent strain of E. coli ever seen contains DNA sequences from plague bacteria."

19 Jan 2016

NIST researchers simulate new method for fast, precise DNA sequencing

Researchers at the National Institute of Standards and Technology (NIST) have simulated a new concept for rapid, accurate gene sequencing by pulling a DNA molecule through a tiny, chemically activated hole in graphene--an ultrathin sheet of carbon atoms--and detecting changes in electrical current.

19 Jan 2016

New blood biomarkers could lead to better evaluation of treatment for patients with PAH

New blood biomarkers reflecting vasoreactivity in lung blood vessels of patients with heart- and lung disease, can lead to simplified diagnostics and better evaluation of treatment for patients with the condition pulmonary arterial hypertension (PAH).

18 Jan 2016

New method helps generate cardiac cells for heart disease studies, drug discovery

For a team of Vanderbilt investigators trying to generate heart muscle cells from stem cells, a piece of broken equipment turned out to be a good thing.

18 Jan 2016

Scientists develop wireless brain sensors

A team of neurosurgeons and engineers has developed wireless brain sensors that monitor intracranial pressure and temperature and then are absorbed by the body, negating the need for surgery to remove the devices.

18 Jan 2016

UM SOM selected to work with BARDA to develop radiologic and nuclear countermeasures

University of Maryland School of Medicine Department of Radiation Oncology Chair and Professor William F. Regine, MD, FACR, FACRO, and UM SOM Dean E. Albert Reece, MD, PhD, MBA, announced today that researchers at the UM SOM have been selected as key contractors by the Biomedical Advanced Research and Development Authority, for its Radiation Nuclear Animal Model Development program.

18 Jan 2016

UConn-led researchers identify specific gene linked to Hajdu-Cheney syndrome

Fragile bones are usually an old person's affliction, but sometimes children are born with them. Now, a team of researchers led by UConn professor Ernesto Canalis has shown in mice that a specific gene can cause the disease, called Hajdu-Cheney syndrome. Overabundant bone-absorbing cells may be causing the disorder's characteristic bone loss, and the researchers hope to find a potential treatment.

18 Jan 2016

Health Canada approves immunotherapy clinical study to treat Epstein-Barr virus-related lymphomas

Health Canada recently approved, for the first time in Canada, a clinical project for a Phase I study aimed at treating lymphomas associated with the Epstein-Barr virus (EBV) through adoptive cellular immunotherapy that is specific to EBV.

18 Jan 2016

PK molecule could be a target for vascular complications linked to type 1 diabetes

In an article published ahead of print on November 24, 2015 in the journal Diabetes (available at http://dx.doi.org/10.2337/db15-0930), researchers from the Medical University of South Carolina, the American University of Beirut, and Case Western Reserve University report that a molecule called pre-kallikrein (PK) could be a target for the vascular complications associated with type 1 diabetes.

18 Jan 2016

The Mobile App That's Making Prescribing Drugs Easier and Safer

News-Medical speaks to Dr. Volpe about the development of an app that allows physicians to access up-to-date medical information at the touch of a button!

From Physicians' Desk Reference (PDR) 18 Jan 2016

UT Southwestern pediatric researchers identify key trigger of neonatal lung disease

Pediatric researchers at UT Southwestern Medical Center have identified a key component of the pathogenesis of bronchopulmonary dysplasia (BPD), a devastating and sometimes fatal lung disease that affects premature infants. Their findings clarify what prompts the inflammatory response that results in BPD, which previously had been unclear.

18 Jan 2016

UGA study helps solve mystery of how African trypanosomes communicate

While scientists have known for years that African trypanosomes cause sleeping sickness, they've been left scratching their heads as to how these tiny single-celled organisms communicate. A University of Georgia study, published Jan. 14 in the journal Cell, helps solve this mystery.

18 Jan 2016

Taking up new mental challenges may help maintain cognitive vitality

One of the greatest challenges associated with the growing numbers of aged adults is how to maintain a healthy aging mind. Taking up a new mental challenge such as digital photography or quilting may help maintain cognitive vitality, say researchers reporting in Restorative Neurology and Neuroscience.

18 Jan 2016

Researchers reveal biological connection between obesity and colorectal cancer risk

Obesity has long been associated with increased risk of colorectal cancer, but the link has never been understood. Now, a research team led by investigators at Thomas Jefferson University has revealed the biological connection, and in the process, has identified an approved drug that might prevent development of the cancer.

18 Jan 2016

Findings offer potential new therapeutic target to boost strength of heart muscle contractions

Researchers at UT Southwestern Medical Center have identified a previously unrecognized small protein in cells of the human heart that plays a key role in heart muscle contraction. The protein is made from an RNA that was previously believed to be a blank or non-coding RNA, suggesting there may be many other small 'non-coding' segments that play important biological roles.

18 Jan 2016

Rockefeller University researchers identify new mechanism involved in early stem cell development

Stem cells work throughout our lives as a sort of handyman, repairing damaged tissues and renewing some normal ones, like the skin we shed. Scientists have come to understand much about how stem cells function when we are adults, but less is known about where these stem cells come from to begin with, as an embryo is developing.

18 Jan 2016

Quad partners with University of Massachusetts to evaluate performance of novel cell separation solution

The rapid growth of cell-based immunotherapy research has led to an increase in demand for methods to isolate specific immune cell populations from heterogeneous samples with high viability, purity and recovery efficiency. Quad Technologies ("Quad"), is meeting this need with its MagCloudz™ Streptavidin Cell Separation Kits and has partnered with The University of Massachusetts Medical School to evaluate the performance of its novel cell separation solution for the enrichment and purification of CD3+ T-cells from human umbilical cord blood.

18 Jan 2016

Scientists find new way to re-engineer body’s immune system to target cancer

Scientists have demonstrated a new way of re-engineering the body’s immune system to target cancer, paving the way for a new generation of drugs, unprecedented in safety and effectiveness.

18 Jan 2016

Researchers identify origins of aggressive childhood lymphoma

The origins of a type of aggressive childhood lymphoma have been found, giving hope that new drugs could be designed to prevent the disease coming back after treatment.

18 Jan 2016

Anti-cancer drug uses 50 times less chemo to effectively destroy drug-resistant lung cancer

The cancer drug paclitaxel just got more effective. For the first time, researchers from the University of North Carolina at Chapel Hill have packaged it in containers derived from a patient's own immune system, protecting the drug from being destroyed by the body's own defenses and bringing the entire payload to the tumor.

18 Jan 2016

Medical Science News

Antivirulence antibiotics could evade resistance longer than traditional antibiotics

NIST researchers simulate new method for fast, precise DNA sequencing

New blood biomarkers could lead to better evaluation of treatment for patients with PAH

New method helps generate cardiac cells for heart disease studies, drug discovery

Scientists develop wireless brain sensors

UM SOM selected to work with BARDA to develop radiologic and nuclear countermeasures

UConn-led researchers identify specific gene linked to Hajdu-Cheney syndrome

Health Canada approves immunotherapy clinical study to treat Epstein-Barr virus-related lymphomas

PK molecule could be a target for vascular complications linked to type 1 diabetes

The Mobile App That's Making Prescribing Drugs Easier and Safer

UT Southwestern pediatric researchers identify key trigger of neonatal lung disease

UGA study helps solve mystery of how African trypanosomes communicate

Taking up new mental challenges may help maintain cognitive vitality

Researchers reveal biological connection between obesity and colorectal cancer risk

Findings offer potential new therapeutic target to boost strength of heart muscle contractions

Rockefeller University researchers identify new mechanism involved in early stem cell development

Quad partners with University of Massachusetts to evaluate performance of novel cell separation solution

Scientists find new way to re-engineer body’s immune system to target cancer

Researchers identify origins of aggressive childhood lymphoma

Anti-cancer drug uses 50 times less chemo to effectively destroy drug-resistant lung cancer

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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