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NIMH signs agreement to establish collaborative brain donation initiative for autism research

The National Institute of Mental Health has signed an agreement to establish a collaborative, nationwide effort for the collection, storage, and distribution of postmortem human brain tissue for the benefit of autism research. The agreement with Foundation Associates LLC will coordinate the efforts of two independent networks of human brain tissue repositories, the National Institutes of Health NeuroBioBank and the Autism BrainNet.

18 Nov 2015

Discovery of new virus could pave way for stopping mosquito-borne disease outbreaks

Australian scientists have discovered a new virus carried by one of the country's most common pest mosquitoes. The new virus -- known as Parramatta River virus -- infects only mosquitoes and doesn't pose any direct health risks to people, according to University of Queensland (UQ) and University of Sydney researchers.

18 Nov 2015

Johns Hopkins scientists use gene-based tests to distinguish precancerous cysts from harmless cysts

In a "look-back" analysis of data stored on 130 patients with pancreatic cysts, scientists at Johns Hopkins have used gene-based tests and a fixed set of clinical criteria to more accurately distinguish precancerous cysts from those less likely to do harm. The findings may eventually help some patients in real time safely avoid surgery to remove harmless cysts.

18 Nov 2015

York researchers discover innovative method to make new medicines

Inspired by the classic 'ball-in-a-cup' children's toy, researchers at the University of York have discovered an innovative method to make medicinally important molecules.

18 Nov 2015

TSRI scientists discover first-in-class compounds that target persistent tuberculosis

Tuberculosis has been infecting humans for several millennia, making it one of the most horribly successful diseases in history. Today, it is still a major killer, responsible for some 1.5 million deaths each year.

18 Nov 2015

Bone protein can inhibit prostate cancer metastasis to bone

Scientists from Lawrence Livermore National Laboratory in collaboration with researchers from University of California campuses at Merced and Davis have found that a secreted protein predominantly expressed in bone inhibits prostate cancer metastasis to bone.

18 Nov 2015

Coating implants with certain 'activator' can prevent S. aureus infection

Biofilms frequently coat the surfaces of catheters, and of various medical implants and prostheses, where they can cause life-threatening infections. New research at the Sahlgrenska Academy show that coating implants with a certain "activator" can prevent Staphylococcus aureus, the leading cause of hospital-acquired infections, from forming biofilms.

18 Nov 2015

Simple microRNA sensor holds promise for prognosis, treatment of pancreatic and other cancers

A simple, ultrasensitive microRNA sensor developed and tested by researchers from the schools of science and medicine at Indiana University-Purdue University Indianapolis and the Indiana University Melvin and Bren Simon Cancer Center holds promise for the design of new diagnostic strategies and, potentially, for the prognosis and treatment of pancreatic and other cancers.

18 Nov 2015

USC discoveries propose promising method to eliminate pain associated with tooth decay

Dual discoveries at USC propose a promising method to regrow nonliving hard tissue, lessening or even eliminating pain associated with tooth decay, which the National Institutes of Health calls the most prevalent chronic disease.

18 Nov 2015

Study provides biochemical links between genes linked to autism and the inhibition of nerve cells

A study led by the University of Utah School of Medicine provides new insights into how the subtle changes within cells, caused by disruptions in a gene called Kirrel3, could underlie some types of intellectual disability and autism.

18 Nov 2015

TSRI researchers have new weapons to combat HIV

Scientists at The Scripps Research Institute have new weapons in the fight against HIV. Their new study, published November 17, 2015 as the cover article of the journal Immunity, describes four prototype antibodies that target a specific weak spot on the virus. Guided by these antibodies, the researchers then mimicked the molecular structure of a protein on HIV when designing their own potential HIV vaccine candidate.

18 Nov 2015

NSU collaborates with Karolinska Institutet to conduct cell-based biomedical research

Nova Southeastern University is now at the forefront of conducting pioneering cell-based biomedical research with the launch of the new NSU Cell Therapy Institute, an international collaboration with prominent medical research scientists from Sweden's world-renowned Karolinska Institutet (KI).

17 Nov 2015

MicroRNA reduces tumor growth, increases cell death in castration-resistant prostate cancer

Researchers at the UC Davis Comprehensive Cancer Center have shown that the microRNA, miR-124, reduced tumor growth and increased cell death in castration-resistant prostate cancer.

17 Nov 2015

Researchers identify genetic mutation associated with reckless drunken behavior

University of Helsinki researchers have identified a genetic mutation which renders carriers susceptible to particularly impulsive and reckless behaviour when drunk. More than one hundred thousand Finns carry this mutation.

17 Nov 2015

Researchers use large-scale computer modeling to show effects of confinement on cell macromolecules

Using large-scale computer modeling, researchers have shown the effects of confinement on macromolecules inside cells -- and taken the first steps toward simulating a living cell, a capability that could allow them to ask 'what-if' questions impossible to ask in real organisms.

17 Nov 2015

RNA-based drugs provide many advantages over CRISPR/Cas9 gene editing system

In just the past few years, researchers have found a way to use a naturally occurring bacterial system known as CRISPR/Cas9 to inactivate or correct specific genes in any organism. CRISPR/Cas9 gene editing activity runs continuously, though, leading to risk of additional editing at unwanted sites. Now, researchers at University of California, San Diego School of Medicine, Ludwig Cancer Research and Isis Pharmaceuticals demonstrate a commercially feasible way to use RNA to turn the CRISPR-Cas9 system on and off as desired -- permanently editing a gene, but only temporarily activating CRISPR-Cas9.

17 Nov 2015

Structural differences in key brain region linked to hallucinations in people diagnosed with schizophrenia

People diagnosed with schizophrenia who are prone to hallucinations are likely to have structural differences in a key region of the brain compared to both healthy individuals and people diagnosed with schizophrenia who do not hallucinate, according to research published today.

17 Nov 2015

Study may lead to development of highly accurate screening test for early-stage ovarian cancer

Studying blood serum compounds of different molecular weights has led scientists to a set of biomarkers that may enable development of a highly accurate screening test for early-stage ovarian cancer.

17 Nov 2015

Myriad RBM's DiscoveryMAP platform identifies protein biomarkers linked to CV events in diabetes patients

Myriad RBM, a wholly-owned subsidiary of Myriad Genetics, Inc., today announced that its DiscoveryMAP platform successfully identified combinations of 15 protein biomarkers associated with cardiovascular (CV) events or death in people with pre-diabetes or early type 2 diabetes, according to a study published by the journal Circulation.

17 Nov 2015

Study reveals why colorectal cancer still returns in some patients after treatment

Cetuximab, marketed as Erbitux, is one of the key therapies for metastatic colorectal cancer. Yet the cancer still returns in some patients, shortening overall survival.

17 Nov 2015

Medical Science News

NIMH signs agreement to establish collaborative brain donation initiative for autism research

Discovery of new virus could pave way for stopping mosquito-borne disease outbreaks

Johns Hopkins scientists use gene-based tests to distinguish precancerous cysts from harmless cysts

York researchers discover innovative method to make new medicines

TSRI scientists discover first-in-class compounds that target persistent tuberculosis

Bone protein can inhibit prostate cancer metastasis to bone

Coating implants with certain 'activator' can prevent S. aureus infection

Simple microRNA sensor holds promise for prognosis, treatment of pancreatic and other cancers

USC discoveries propose promising method to eliminate pain associated with tooth decay

Study provides biochemical links between genes linked to autism and the inhibition of nerve cells

TSRI researchers have new weapons to combat HIV

NSU collaborates with Karolinska Institutet to conduct cell-based biomedical research

MicroRNA reduces tumor growth, increases cell death in castration-resistant prostate cancer

Researchers identify genetic mutation associated with reckless drunken behavior

Researchers use large-scale computer modeling to show effects of confinement on cell macromolecules

RNA-based drugs provide many advantages over CRISPR/Cas9 gene editing system

Structural differences in key brain region linked to hallucinations in people diagnosed with schizophrenia

Study may lead to development of highly accurate screening test for early-stage ovarian cancer

Myriad RBM's DiscoveryMAP platform identifies protein biomarkers linked to CV events in diabetes patients

Study reveals why colorectal cancer still returns in some patients after treatment

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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