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Researchers find molecular mechanism that may be responsible for development of amyloidoses

A team of local researchers has proposed a molecular mechanism that may be responsible for the development of life-threatening diseases called amyloidoses. The best known of such diseases is Alzheimer's disease (AD), but there are many others that are receiving increased scrutiny, in part because of mounting evidence linking them to atherosclerosis and aging.

13 Nov 2015

New study provides possible way to overcome stem cell research’s developmental arrest problem

Johns Hopkins researchers report that a new study of mouse cells has revealed reasons why attempts to grow stem cells to maturity in the laboratory often fail, and provided a possible way to overcome such "developmental arrest."

13 Nov 2015

Study highlights possible inaccuracies in thyroid cancer detection tests

Protein biomarkers are used to test for cancer before and after surgeries to remove tumors. To test thyroid malignancy, many biomarkers are tested separately to confirm cancer. However, new research from Michigan Technological University shows that the detection tests that measure two major biomarkers to diagnose thyroid cancer may be inaccurate.

13 Nov 2015

Presence of connexin proteins suppresses primary tumor growth

How does a protein called connexin put the clamps on cancer? Researchers in the School of Medicine at The University of Texas Health Science Center at San Antonio today reported an explanation.

13 Nov 2015

Study: Eating sweet foods causes the brain to form memories that may control eating behaviors

Eating sweet foods causes the brain to form a memory of a meal, according to researchers at Georgia State University, Georgia Regents University and Charlie Norwood VA Medical Center.

13 Nov 2015

Experimental drug candidate aimed at combating Alzheimer's disease has anti-aging effects

Salk Institute researchers have found that an experimental drug candidate aimed at combating Alzheimer's disease has a host of unexpected anti-aging effects in animals.

13 Nov 2015

U of I scientists show that tomato component reduces growth of prostate tumors in animal models

Years of research in University of Illinois scientist John Erdman's laboratory have demonstrated that lycopene, the bioactive red pigment found in tomatoes, reduces growth of prostate tumors in a variety of animal models. Until now, though, he did not have a way to trace lycopene's metabolism in the human body.

13 Nov 2015

TGen: PPF drug could help treat patients with deadly brain cancer

In a significant breakthrough, the Translational Genomics Research Institute has identified a drug, propentofylline or PPF, that could help treat patients with deadly brain cancer.

13 Nov 2015

Vanderbilt study could lead to development of new drugs that relieve pain without causing vascular effects

It's been about a decade since the promise of COX-2 inhibitors -- drugs that relieve arthritis pain and inflammation without the gastrointestinal side effects of other painkillers -- was tempered by the realization that they could cause heart problems in some patients.

13 Nov 2015

Intake of gluten increases risk of celiac disease in children

Intake of gluten up until two years of age increases risk of celiac disease at least two-fold in children with genetic risk factors for this disease, according a study published in Clinical Gastroenterology and Hepatology the official clinical practice journal of the American Gastroenterological Association.

13 Nov 2015

Mayo Clinic's Florida campus awarded NIH grant to identify vascular risk factors in aging and dementia

Mayo Clinic's Florida campus was awarded a $5.3 million grant from the National Institutes of Health to identify vascular risk factors in aging and dementia, and translate that knowledge into studying potential targets for treatment.

12 Nov 2015

Mayo Clinic investigators discover novel mechanism linked to diabetes risk

Researchers at Mayo Clinic have discovered an unexpected effect from a gene known to increase diabetes risk. They assumed that the specific allele in the gene TCF7L2 which increases the risk of type 2 diabetes, impairs insulin production in response to increased insulin resistance. Some slight evidence of that was found, but more significantly the researchers discovered that this variant impaired a person's ability to balance blood sugar (glucose) by suppressing glucagon - the hormone that raises the level of glucose in the bloodstream.

12 Nov 2015

Different types of asthma respond differently to new experimental treatment

University of Queensland research into the effects of dust mite and cockroach allergens has found that different types of asthma respond differently to a new experimental treatment.

12 Nov 2015

UCSF-led researchers map out melanoma's genetic trajectories

An international team of scientists led by UC San Francisco researchers has mapped out the genetic trajectories taken by melanoma as it evolves from early skin lesions, known as precursors, to malignant skin cancer, which can be lethal when it invades other tissues in the body.

12 Nov 2015

HEAL Project aims to regenerate human knees and limbs within 15 years

On Veteran's Day the University of Connecticut announced the launch of its new grand research challenge: regeneration of a human knee within 7 years, and an entire limb within 15 years.

12 Nov 2015

Meta-analysis supports that intake of tree nuts lowers risk of cardiovascular disease

In a study published yesterday in the American Journal of Clinical Nutrition*, researchers performed a systematic review and meta-analysis of controlled trials to investigate the effects of tree nuts (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts) on blood lipids, lipoproteins, blood pressure and inflammation in adults 18 years and older without prevalent cardiovascular disease (CVD).

12 Nov 2015

CHOP researchers delay symptoms, extend lifespan in animal model of Batten disease

Researchers have taken a significant step forward in developing gene therapy against a fatal neurodegenerative disease that strikes children. By delivering a working version of a gene to produce a key enzyme that is lacking in Batten disease, the scientists delayed symptoms and extended lifespan in dogs with a comparable disease.

12 Nov 2015

Moffitt Cancer Center study finds link between common gene mutations and tumor immune surveillance

Learning if a lung cancer patient has genetic mutations can help oncologists determine the best approach to treatment. There are four gene mutations (KRAS, TP53, STK11, and EGFR) that most commonly occur in lung cancer; however, there are limited effective therapies to target these mutations. With this in mind, Moffitt Cancer Center performed an extensive genetic analysis of lung cancer specimens to unravel how mutations in the two of those genes (TP53 and STK11) contribute to the biology of lung cancer and patient outcomes.

12 Nov 2015

Berkeley Lab scientists identify genetic factors that influence neurological disorders and body weight

Many neurological disorders, such as Parkinson's disease and Alzheimer's disease, are marked by impaired motor skills. In addition, growing evidence suggests there's a link between some neurodegenerative diseases and body weight. A recent NIH study, for example, found that adults who are obese or overweight at midlife may be at risk for earlier onset of Alzheimer's disease.

12 Nov 2015

Research brings scientists one step closer to developing human-like artificial intelligence

Making a computer that learns and remembers like a human brain is a daunting challenge. The complex organ has 86 billion neurons and trillions of connections -- or synapses -- that can grow stronger or weaker over time. But now scientists report in ACS' journal Nano Letters the development of a first-of-its-kind synthetic synapse that mimics the plasticity of the real thing, bringing us one step closer to human-like artificial intelligence.

12 Nov 2015

Medical Science News

Researchers find molecular mechanism that may be responsible for development of amyloidoses

New study provides possible way to overcome stem cell research’s developmental arrest problem

Study highlights possible inaccuracies in thyroid cancer detection tests

Presence of connexin proteins suppresses primary tumor growth

Study: Eating sweet foods causes the brain to form memories that may control eating behaviors

Experimental drug candidate aimed at combating Alzheimer's disease has anti-aging effects

U of I scientists show that tomato component reduces growth of prostate tumors in animal models

TGen: PPF drug could help treat patients with deadly brain cancer

Vanderbilt study could lead to development of new drugs that relieve pain without causing vascular effects

Intake of gluten increases risk of celiac disease in children

Mayo Clinic's Florida campus awarded NIH grant to identify vascular risk factors in aging and dementia

Mayo Clinic investigators discover novel mechanism linked to diabetes risk

Different types of asthma respond differently to new experimental treatment

UCSF-led researchers map out melanoma's genetic trajectories

HEAL Project aims to regenerate human knees and limbs within 15 years

Meta-analysis supports that intake of tree nuts lowers risk of cardiovascular disease

CHOP researchers delay symptoms, extend lifespan in animal model of Batten disease

Moffitt Cancer Center study finds link between common gene mutations and tumor immune surveillance

Berkeley Lab scientists identify genetic factors that influence neurological disorders and body weight

Research brings scientists one step closer to developing human-like artificial intelligence

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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