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New drug cocktail may show promise in NSCLC patients

A drug approved by the Food and Drug Administration for melanoma in combination with a common cholesterol-lowering drug may show promise in controlling cancer growth in patients with non-small cell lung cancer (NSCLC), according to new research from the Icahn School of Medicine at Mount Sinai.

3 Feb 2016

MYB-QKI fusion gene that drives pediatric low-grade gliomas poses a triple threat

Oncology researchers have discovered that an abnormal fused gene that drives pediatric brain tumors poses a triple threat, operating simultaneously through three distinct biological mechanisms—the first such example in cancer biology.

2 Feb 2016

Saliva gland test may help diagnose early Parkinson's disease

Researchers from Mayo Clinic in Arizona and Banner Sun Health Research Institute have determined that testing a portion of a person's submandibular gland may be a way to diagnose early Parkinson's disease. The study was published this month in Movement Disorders, the official journal of the International Parkinson and Movement Disorders Society.

2 Feb 2016

'Junk' DNA suppresses breast cancer

Supposed "junk" DNA, found in between genes, plays a role in suppressing cancer, according to new research by Universities of Bath and Cambridge.

2 Feb 2016

Immunological changes during pregnancy may influence response to influenza vaccination

In a study to be presented on Feb. 5 in an oral concurrent session at 1:15 p.m. EST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in Atlanta, researchers will present findings from a study titled, T-follicular helper (Thf) cell expansion varies by trimester after influenza vaccination in pregnancy.

2 Feb 2016

New way to more efficiently deliver CRISPR/Cas9 therapeutic to mice with Tyrosinemia type I

University of Massachusetts Medical School researchers have found a way to more efficiently delivery a CRISPR/Cas9 therapeutic to adult mice with the metabolic disease Tyrosinemia type I that may also prove to be safer for use in humans.

2 Feb 2016

Understanding crucial role of 'healthy' brain in preventing memory failures linked to Alzheimer's disease

The mechanisms underlying the stability and plasticity of neural circuits in the hippocampus, the part of the brain responsible for spatial memory and the memory of everyday facts and events, has been a major focus of study in the field of neuroscience. Understanding precisely how a "healthy" brain stores and processes information is crucial to preventing and reversing the memory failures associated with Alzheimer's disease (AD), the most common form of late-life dementia.

2 Feb 2016

Maternal diet during pregnancy and lactation leads to epigenetic changes in offspring

As the study shows, a high-fat diet during pregnancy and lactation leads to epigenetic changes in the offspring. These changes affect metabolic pathways regulated by the gut hormone GIP, whereby the adult offspring are more susceptible to obesity and insulin resistance, the precursor to type 2 diabetes. Similar mechanisms cannot be ruled out in humans, according to Pfeiffer.

2 Feb 2016

Study provides new insights into breast cancer metastasis

It has long been thought that cancer metastasizes, or spreads, when a single cancer cell escapes from the original tumor, travels through the bloodstream and sets up shop in distant organs. However, a growing body of evidence suggests that these bad actors don't travel alone; instead they migrate through the body in cellular clusters, like gangs.

2 Feb 2016

Block copolymer hydrogels facilitate cryoprotection of red blood cells and increase tissue engineering

Freezing of medical tissue and cells usually requires the addition of cryopreservatives, although the added compounds can have undesired effects in subsequent applications.

2 Feb 2016

Biochemical compound demonstrates increasing potential for use in cancer imaging

In the paper, an international team reviewed studies conducted over the past 30 years on a particular tracer, called “18F-FLT,” and found that it has the potential to improve diagnostic imaging, and thus treatment, of some cancers.

2 Feb 2016

Study shows several Envigo rat models susceptible to genital HSV-2 infection

A scientific collaboration between Envigo and the Department of Infectious Disease at the University of Gothenburg, Sweden has unveiled study findings into rat models and their susceptibility to intra-vaginal herpes simplex virus-2 (HSV-2) infection.

2 Feb 2016

Researchers identify definitive genetic defect in angiocentric gliomas

Diagnosis and treatment decisions for a recently recognized type of children's brain tumor should be improved by the discovery of the genetic mechanism that causes it, say researchers who identified the unusual DNA abnormality in angiocentric gliomas.

2 Feb 2016

Gender associated with risk of cardiovascular recurrence in adults

Sex (biological and physiological characteristics) differences are increasingly being studied to assess symptoms, risk factors and outcomes for various diseases. Now, a new pan-Canadian study led by a team from the Research Institute of the McGill University Health Centre, suggests that gender rather than sex is associated with the risk of recurrence of cardiovascular events in adults.

2 Feb 2016

Radiation could increase responses to innovative immune-based therapeutic approaches to fight cancer

A team of Georgia State University researchers is fighting cancers using a combination of therapies and recently found ways that radiation could maximize responses to novel immune-based therapeutic approaches to fight cancer.

1 Feb 2016

New study lays foundation for future gene replacement therapies to treat ALS patients

Scientists have demonstrated for the first time that it is possible to specifically modify gene expression in diseased upper motor neurons, brain cells that break down in ALS.

1 Feb 2016

Rockland announces availability of new human melanoma cell lines

Rockland Immunochemicals, Inc. announces the availability of a new collection of human melanoma cell lines that have been developed and characterized over several decades in the laboratory of Meenhard Herlyn, D.V.M., D.Sc., Caspar Wistar Professor in Melanoma Research, Director of the Melanoma Research Center, and professor in the Molecular and Cellular Oncogenesis Program at The Wistar Institute in Philadelphia.

1 Feb 2016

Rochester scientists identify stem cells capable of skull formation, craniofacial bone repair in mice

A team of Rochester scientists has, for the first time, identified and isolated a stem cell population capable of skull formation and craniofacial bone repair in mice--achieving an important step toward using stem cells for bone reconstruction of the face and head in the future, according to a new paper in Nature Communications.

1 Feb 2016

Researchers show how bacterial colony protects itself against toxic substances

Bacterial populations move over surfaces in coordinated way known as swarming, which allows them to spread further over organs and tissues and increases the virulence of the infection. This movement is driven by the action of the flagella and the chemoreceptors, the systems responsible for identifying chemical compounds in the environment and which are anchored at the poles of their cells, forming highly organised structures, of which the protein CheW forms part.

1 Feb 2016

New technology could help identify, characterize biologically active molecules produced by living cells

Gene sequencing company Illumina recently made big waves by announcing a new spinoff, Grail, dedicated to building a test for cancer by sequencing tumor DNA fragments found in blood. The company also reported plans for a separate project to identify single cells and tag them for later analysis.

1 Feb 2016

Medical Science News

New drug cocktail may show promise in NSCLC patients

MYB-QKI fusion gene that drives pediatric low-grade gliomas poses a triple threat

Saliva gland test may help diagnose early Parkinson's disease

'Junk' DNA suppresses breast cancer

Immunological changes during pregnancy may influence response to influenza vaccination

New way to more efficiently deliver CRISPR/Cas9 therapeutic to mice with Tyrosinemia type I

Understanding crucial role of 'healthy' brain in preventing memory failures linked to Alzheimer's disease

Maternal diet during pregnancy and lactation leads to epigenetic changes in offspring

Study provides new insights into breast cancer metastasis

Block copolymer hydrogels facilitate cryoprotection of red blood cells and increase tissue engineering

Biochemical compound demonstrates increasing potential for use in cancer imaging

Study shows several Envigo rat models susceptible to genital HSV-2 infection

Researchers identify definitive genetic defect in angiocentric gliomas

Gender associated with risk of cardiovascular recurrence in adults

Radiation could increase responses to innovative immune-based therapeutic approaches to fight cancer

New study lays foundation for future gene replacement therapies to treat ALS patients

Rockland announces availability of new human melanoma cell lines

Rochester scientists identify stem cells capable of skull formation, craniofacial bone repair in mice

Researchers show how bacterial colony protects itself against toxic substances

New technology could help identify, characterize biologically active molecules produced by living cells

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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