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WPI researchers awarded $1.3 million NIH grant to study use of copper to battle bacterial invader

Copper is an essential micronutrient that all organisms need to maintain healthy metabolism. But unless it is bound to proteins, copper is also toxic to cells. With a $1.3 million award from the National Institutes of Health, researchers at Worcester Polytechnic Institute will conduct a systematic study of copper in the bacteria Pseudomonas aeruginosa (P. aeruginosa), a leading cause of hospital-associated infections that is increasingly resistant to antibiotics, with the hope of discovering new drug targets that might allow cells in the body to use copper to fight back against this bacterial invader.

25 Nov 2015

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a study in The Journal of Infectious Diseases.

25 Nov 2015

Run-and-scan strategy more efficient than tracking strategy in finding target

It's dinnertime, and the smell of delicious food makes your tummy rumble. However, it's dark because of a powercut and you can't see very clearly. Should you try to 'follow your nose' to locate food? Or should you simply guess and peek into the kitchen, or the dining room or the veranda - the likeliest places for dinner to be served? A recent study shows that the latter method - dubbed 'run-and-scan' - may actually be more efficient in finding your target than just following your nose.

25 Nov 2015

Physical exercise can enhance development of new brain cells

Exercise can enhance the development of new brain cells in the adult brain, a process called adult neurogenesis. These newborn brain cells play an important role in learning and memory. A new study has determined that mice that spent time running on wheels not only developed twice the normal number of new neurons, but also showed an increased ability to distinguish new objects from familiar objects.

25 Nov 2015

RPCI-led researchers identify strategies to prevent acute kidney injury

Acute kidney injury (AKI), also known as acute renal failure, is one of the main contributors to death and disability worldwide, yet no preventive treatment for the condition has been established. In a new study published in the journal Cell Death and Differentiation, a team of researchers led by scientists from Roswell Park Cancer Institute reports that they have identified 10 genes whose inhibition appears to protect kidney cells.

25 Nov 2015

Stress-related gene affects post-concussive symptoms after car crashes

Variations in a gene that affect the body's responses to stress influence the risk of developing so-called post-concussive symptoms (PCS) after car crashes, reports a study in Psychosomatic Medicine: Journal of Biobehavioral Medicine, the official journal of the American Psychosomatic Society. The journal is published by Wolters Kluwer.

25 Nov 2015

Researchers find lower levels of omega-3 fatty acids in people with bipolar disorder

People with bipolar disorder have lower levels of certain omega-3 fatty acids that cross the blood-brain barrier compared to those who do not, according to researchers from Penn State College of Medicine and the National Institutes of Health. The finding could have implications for dietary interventions for the disorder.

25 Nov 2015

Research brings scientists closer to understanding mechanisms underlying genomic imprinting process

Research led by Dr. Keiji Tanimoto from the University of Tsukuba, Japan, has brought us closer to understanding the mechanisms underlying the phenomenon of genomic imprinting.

25 Nov 2015

UNC study reveals how specific schizophrenia symptoms linked to distinct brain circuits

Schizophrenia, a severe mental disorder affecting about one in 100 people, is notoriously difficult to diagnose and treat, in large part because it manifests differently in different people. A new study published today in Molecular Neuropsychiatry helps explain why.

25 Nov 2015

Slower aging reduces degeneration related to Parkinson's disease

Humans have long sought to reduce the effects of aging. Now, there may be another reason to continue searching for ways to slow the clock--preventing Parkinson's disease.

25 Nov 2015

Scientists create detailed image of deadly toxin linked to bacterial pneumonia, meningitis, septicaemia

Scientists from the University of Leicester have for the first time created a detailed image of a toxin - called pneumolysin - associated with deadly infections such as bacterial pneumonia, meningitis and septicaemia.

25 Nov 2015

Personal glucose meters can also measure biomarkers in patient's blood, say US scientists

Not only glucose: It is possible that people use their personal glucose meters for the quantification of other biomarkers than glucose in their blood, say American scientists from the University of Illinois.

25 Nov 2015

New sensor can detect estrogen levels in liquids

Estrogen is a tiny molecule, but it can have big effects on humans and other animals. Estrogen is one of the main hormones that regulates the female reproductive system - it can be monitored to track human fertility and is sometimes administered to livestock like cows and sheep to control the reproductive cycle.

25 Nov 2015

UF Health researcher finds simple way to treat immune-related disorder in mice

A University of Florida Health researcher has found a simple, rapid way to treat an immune-related disorder in mice, an approach that could eventually help multiple sclerosis patients after further research.

25 Nov 2015

Scientists show evidence for exchange of lactate between different brain cells

Nerve cells cover their high energy demand with glucose and lactate. Scientists of the University of Zurich now provide new support for this. They show for the first time in the intact mouse brain evidence for an exchange of lactate between different brain cells. With this study they were able to confirm a 20-year old hypothesis.

25 Nov 2015

Fat cells produced from bone marrow may be linked to chronic diseases

Researchers at the University of Colorado Anschutz Medical Campus have found that fat cells produced by stem cells from the bone marrow may be linked to chronic illnesses like diabetes, cardiovascular disease, kidney disease and some cancers.

25 Nov 2015

New collaboration aims to develop novel generation artificial pancreas

Debiotech SA, the ARTORG Center for Biomedical Engineering Research of the University of Bern - and the Division of Endocrinology, Diabetes and Clinical Nutrition of the Bern University Hospital "Inselspital" are proud to announce the start of an exclusive collaboration to develop a novel generation artificial pancreas.

24 Nov 2015

Researchers reveal causal association between aneuploidy and cancer

Publication in Nature Cell Biology: researchers at the Université libre de Bruxelles - ULB Cancer Research Center, U-CRC - show the causal link between aneuploidy and cancer.

24 Nov 2015

Dopamine measurements provides information crucial for human choice

Virginia Tech Carilion Research Institute scientists have reported measurements of dopamine release with unprecedented temporal precision in the brains of people with Parkinson's disease. The measurements, collected during brain surgery as the conscious patients played an investment game, demonstrate how rapid dopamine release encodes information crucial for human choice.

24 Nov 2015

More hormone treatments decrease women's chances of having baby

A Michigan State University study has found that too much of a hormone commonly used during in vitro fertility, or IVF, treatments actually decreases a woman's chances of having a baby.

24 Nov 2015

Medical Science News

WPI researchers awarded $1.3 million NIH grant to study use of copper to battle bacterial invader

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

Run-and-scan strategy more efficient than tracking strategy in finding target

Physical exercise can enhance development of new brain cells

RPCI-led researchers identify strategies to prevent acute kidney injury

Stress-related gene affects post-concussive symptoms after car crashes

Researchers find lower levels of omega-3 fatty acids in people with bipolar disorder

Research brings scientists closer to understanding mechanisms underlying genomic imprinting process

UNC study reveals how specific schizophrenia symptoms linked to distinct brain circuits

Slower aging reduces degeneration related to Parkinson's disease

Scientists create detailed image of deadly toxin linked to bacterial pneumonia, meningitis, septicaemia

Personal glucose meters can also measure biomarkers in patient's blood, say US scientists

New sensor can detect estrogen levels in liquids

UF Health researcher finds simple way to treat immune-related disorder in mice

Scientists show evidence for exchange of lactate between different brain cells

Fat cells produced from bone marrow may be linked to chronic diseases

New collaboration aims to develop novel generation artificial pancreas

Researchers reveal causal association between aneuploidy and cancer

Dopamine measurements provides information crucial for human choice

More hormone treatments decrease women's chances of having baby

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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