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Researchers discover how and where chromosome fragile sites occur in human DNA

Using a novel method they developed to map chromosome breaks in a model organism, the budding yeast, Wenyi Feng, Ph.D., of Upstate Medical University and her colleagues have discovered new information as to how and where chromosome fragile sites can occur in human DNA. These sites are frequently observed in cancer cells and are responsible for causing genomic rearrangements.

15 May 2015

New genomics laboratory in Liberia enables scientists to monitor genetic changes in Ebola virus

Army scientists working to support the Ebola virus outbreak response in West Africa have established the first genomic surveillance capability in Liberia, enabling them to monitor genetic changes in the virus within one week of sample collection. An article describing their work was recently published ahead of print in the online edition of Emerging Infectious Diseases.

15 May 2015

Study evaluates prenatal nutrition and genome-wide DNA patterns in adults exposed to malnutrition

Researchers at Columbia University's Mailman School of Public Health and Leiden University in the Netherlands found that children whose mothers were malnourished at famine levels during the first 10 weeks of pregnancy had changes in DNA methylation known to suppress genes involved in growth, development, and metabolism documented at age 59.

15 May 2015

Smoking-related DNA damage can be detected in cheek swabs

DNA damage caused by smoking can be detected in cheek swabs, finds research published today in JAMA Oncology. The study provides evidence that smoking induces a general cancer program that is also present in cancers which aren't usually associated with it - including breast and gynaecological cancers.

15 May 2015

Profiling normal DNA provides opportunity to identify inherited mutations

As the practice of genetically profiling patient tumors for clinical treatment decision making becomes more commonplace, a recent study from The University of Texas MD Anderson Cancer Center suggests that profiling normal DNA also provides an important opportunity to identify inherited mutations that could be critical for patients and their families.

15 May 2015

Researchers explore how low-level electrical stimulation reduces inflammation

The Feinstein Institute for Medical Research, the research arm of the North Shore-LIJ Health System, and SetPoint Medical Inc., a biomedical technology company, today released the results of research on the therapeutic potential of vagus nerve stimulation. In a paper published by Bioelectronic Medicine, Kevin J. Tracey, MD, and his colleagues at the Feinstein Institute, explore how low-level electrical stimulation interacts with the body's nerves to reduce inflammation, a fundamental goal of bioelectronic medicine.

15 May 2015

Scientists identify new molecules that destroy cancer cells, save healthy ones

Researchers have identified new molecules that kill cancer cells while protecting healthy cells and that could be used to treat a variety of different cancers. The research shines a light on what happens to cells at the moment they become cancerous.

15 May 2015

Researchers report new label-free chemical imaging that provides similar information as molecular stains

Histopathology is a cornerstone of modern biomedical research. Yet, the practice of histopathology has evolved just a few times -- non-specific stains in the late 19th century, immunohistochemical staining in the mid-to-late 20th century and digital imaging/computerized analysis at the turn of the 20th century. In all cases, prepared biopsy samples are stained and examined under a light microscope.

15 May 2015

Allen Institute makes progress in brain research with launch of Allen Cell Types Database

The Allen Institute for Brain Science announced today that it is taking the first major scientific step to create a searchable standards database for the brain with the launch of the Allen Cell Types Database. This first release includes information on the location, electrical activity and shape of more than 240 neurons.

14 May 2015

Ground-breaking discovery could revolutionise lupus treatments

A ground-breaking discovery by Monash University researchers could revolutionise treatments given to lupus sufferers, saving thousands of people each year from serious illness or death caused by secondary infections.

14 May 2015

MO BIO announces launch of PowerMag DNA Clean-Up Kit

MO BIO Laboratories, Inc., the leader in soil, environmental, plant and microbial nucleic acid purification, announces the launch of the PowerMag DNA Clean-Up Kit, for automated, hands-free clean-up of DNA samples that require a secondary purification for removal of PCR inhibitors. This kit features MO BIO's novel ClearMag magnetic bead technology.

14 May 2015

EKF highlighting its expanding range of liquid stable clinical chemistry reagents at Hospitalar 2015

EKF Diagnostics will be highlighting its expanding Stanbio central laboratory clinical chemistry range at Hospitalar, 19–22 May, Sao Paulo, Brazil.

From EKF Diagnostics 14 May 2015

Immunotherapy for kidney cancer - Phase 3 update from Argos Therapeutics at ASCO

Argos is developing AGS-003, which is a fully personalized immunotherapy designed to induce a durable memory T-cell response specific to each patient’s cancer...

14 May 2015

Human microbiome contains unique fingerprints, shows study

A new study shows that the microbial communities we carry in and on our bodies—known as the human microbiome—have the potential to uniquely identify individuals, much like a fingerprint.

14 May 2015

Researchers make major step toward finding target to combat drug-resistant neuroblastoma

Researchers at Children's Hospital Los Angeles have made an important step toward finding a target in the fight against drug-resistant neuroblastoma (NBL), the most common solid malignancy found, outside of the skull, in children.

14 May 2015

Gadusol compound can provide a systemic sunscreen to humans

Researchers have discovered why many animal species can spend their whole lives outdoors with no apparent concern about high levels of solar exposure: they make their own sunscreen.

14 May 2015

MD Anderson researchers find significant clinical variations among liver cancer patients

Significant clinical variations exist among patients with the most common type of liver cancer called hepatocellular carcinoma (HCC), depending on the viral cause of the disease -hepatitis B virus (HBV) or hepatitis C virus (HCV). These differences suggest that hepatitis status should be considered when developing treatment plans for newly diagnosed patients, according to researchers at The University of Texas MD Anderson Cancer Center.

14 May 2015

Medical Science News

Researchers discover how and where chromosome fragile sites occur in human DNA

New genomics laboratory in Liberia enables scientists to monitor genetic changes in Ebola virus

Study evaluates prenatal nutrition and genome-wide DNA patterns in adults exposed to malnutrition

Smoking-related DNA damage can be detected in cheek swabs

Profiling normal DNA provides opportunity to identify inherited mutations

Researchers explore how low-level electrical stimulation reduces inflammation

Scientists identify new molecules that destroy cancer cells, save healthy ones

Researchers report new label-free chemical imaging that provides similar information as molecular stains

Allen Institute makes progress in brain research with launch of Allen Cell Types Database

Ground-breaking discovery could revolutionise lupus treatments

MO BIO announces launch of PowerMag DNA Clean-Up Kit

EKF highlighting its expanding range of liquid stable clinical chemistry reagents at Hospitalar 2015

Immunotherapy for kidney cancer - Phase 3 update from Argos Therapeutics at ASCO

Human microbiome contains unique fingerprints, shows study

Researchers make major step toward finding target to combat drug-resistant neuroblastoma

Gadusol compound can provide a systemic sunscreen to humans

MD Anderson researchers find significant clinical variations among liver cancer patients

Dopamine-producing neurons affect crucial brain functions

Study finds similarity in clinical progression between human patients and Huntington's disease monkeys

Long, non-coding RNAs play a role in heart attacks, strokes and cancer

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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