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Study discover two new mechanisms that govern editing in key neurodevelopmental gene

RNA editing gives organisms a way to adapt the instructions that their DNA provides for making proteins. Few people would have described RNA editing as a simple process, but a new paper in Nature Communications demonstrates the process as more complex and difficult to predict than previously assumed. The study, done in living fruit flies, discovered two new mechanisms that govern editing in a key neurodevelopmental gene.

1 Aug 2013

Using the immune system to control cancer: an interview with Dr. Jedd Wolchok, MD, PhD, Ludwig Center at MSKCC

Cancer immunotherapy aims to recruit a patient’s immune system to recognize cancer as foreign and dangerous and to remove it from the body, as it would an infection.

1 Aug 2013

'Dark matter' in human genome may play role in cancer biology and cell death

The St. Laurent Institute, a non-profit medical research institute focused on the systems biology of disease, today announced in a study published in the July edition of Genome Biology, that genetic matter, previously ignored by the scientific community, may play an important role in cancer.

1 Aug 2013

Novocure uses NovoTTF therapy to treat first recurrent glioblastoma tumor patient

Novocure today announced that Dr. Tatsunori Okamaura, MD, Ph.D., of the Kashiwaba Neurosurgical Hospital in Sapporo, Japan has treated the first patient in Japan with alternating electric field therapy.

1 Aug 2013

Researchers theoretically create large, hollow magnetic cage molecules that could used in drug delivery system

Virginia Commonwealth University researchers have discovered, in theory, the possibility of creating large, hollow magnetic cage molecules that could one day be used in medicine as a drug delivery system to non-invasively treat tumors, and in other emerging technologies.

1 Aug 2013

Cambridge scientists identify molecular 'on/off' switch in malignant germ cell tumours

Cambridge scientists have identified an 'on/off' switch in a type of cancer which typically occurs in the testes and ovaries called 'malignant germ cell tumours'. The research was published today, 01 August, in the journal Cancer Research.

1 Aug 2013

Researchers identify novel approach to enhance tissue repair and organ regeneration

Because most human tissues do not regenerate spontaneously, advances in tissue repair and organ regeneration could benefit many patients with a wide variety of medical conditions.

1 Aug 2013

Report suggests venom immunotherapy can make sufferers less allergic to insect stings

If you think summer insects are done setting their sights on ruining your outdoor gathering, think again. August's hot and dry climate is the perfect breeding ground for insects, especially yellow jackets. And for the millions of Americans allergic to insect stings, these late summer bugs can be deadly.

1 Aug 2013

Scientists reveal biochemical pathway responsible for manufacturing glycoalkaloids

In 1924, Science magazine reported on a fatal case of potato poisoning: James B. Matheney of Vandalia, Illinois, had gathered about one and a half bushels of tubers, which had turned green due to sunlight exposure.

1 Aug 2013

Scientists solve structure of infection tool used by Yersinia bacterium

Abdominal pain, fever, diarrhoea -- these symptoms could point to an infection with the bacterium Yersinia. The bacterium's pathogenic potential is based on a syringe-like injection apparatus called injectisome.

1 Aug 2013

Montreal scientists develop novel approach for scanning entire genome

Recent technological developments in genomics have revealed a large number of genetic influences on common complex diseases, such as diabetes, asthma, cancer or schizophrenia. However, discovering a genetic variant predisposing to a disease is only a first step. To apply this knowledge towards prevention or cure, including tailoring treatment to the patient's genetic profile -also known as personalized medicine - we need to know how this genetic variant affects health.

1 Aug 2013

Rheonix, Life Technologies sign joint development agreement for molecular testing platform

Rheonix, Inc., a developer of fully automated molecular testing solutions, and Life Technologies Corp., a global leader in the life sciences tools and diagnostic markets, have entered into a joint development agreement to introduce a molecular testing platform for their Applied Markets business.

1 Aug 2013

Oxytocin hormone affects men and women differently, research finds

"The Love Hormone", Oxytocin affects men and women differently in social contexts- in men it improves the ability to identify competitive relationships whereas in women it facilitates the ability to identify kinship. "These findings are in agreement with previous studies on the social differences between the sexes: women tend to be more communal and familial in their behavior, whereas men are more inclined to be competitive and striving to improve their social status", said Prof. Simone Shamay-Tsoory from the Dept. of Psychology at the University of Haifa who led the research.

1 Aug 2013

Naked mole rat: A fitting model for finding novel ways to fight cancer

Mice and rats have long since been a standard animal model for cancer research, mainly due to their short lifespan of four years on average and high incidence of cancer. Naked mole rats however, are a mystery among mammals. This social tiny African subterranean rodent has a maximum lifespan exceeding 30 years and most surprisingly, is cancer-resistant.

1 Aug 2013

Transmembrane protein NG2 controls orientation of cell migration toward the wound

When the central nervous system is injured, oligodendrocyte precursor cells migrate to the lesion and synthesize new myelin sheaths on demyelinated axons. Scientists at the Institute of Molecular Cell Biology at Johannes Gutenberg University Mainz have now discovered that a distinct protein regulates the direction and movement of OPC toward the wound. The transmembrane protein NG2, which is expressed at the surface of OPCs and down-regulated as they mature to myelinating oligodendrocytes, plays an important role in the reaction of OPC to wounding.

1 Aug 2013

New approach could provide alternative treatment for chemotherapy-resistant breast cancer

A new way to target a breast cancer cells' appetite for over-indulging in sugar, that could provide an alternative treatment for chemotherapy resistant breast cancer, is being developed by Breast Cancer Campaign scientists at the University of Southampton.

1 Aug 2013

Finding could influence effectiveness of bone marrow transplants for late-stage leukemia

Eight years ago, two former Stanford University postdoctoral fellows, one of them still in California and the other at the Harvard Stem Cell Institute in Cambridge, began exchanging theories about why patients with leukemia stop producing healthy blood cells. What was it, they asked, that caused bone marrow to stop producing normal blood-producing cells?

1 Aug 2013

Miniscule signaling molecule plays critical role in certain acute and chronic diseases

Scientists seeking to harness the healing power of a miniscule signaling molecule that plays a critical role in certain acute and chronic diseases have been awarded a Program Project Grant (PPG) of nearly $10 million by the National Heart, Lung and Blood Institute of the National Institutes of Health.

1 Aug 2013

Novel protein could lead to development of new drugs to treat variety of cancers

In cancer research, discovering a new protein that plays a role in cancer is like finding a key and a treasure map: follow the clues and eventually there could be a big reward. At least that's the hope from a new study published in the journal Nature that discovered a novel protein called ceramide-1 phosphate transport protein (CPTP) -- a finding that could eventually lead to the development of new drugs to treat a variety of cancers and other conditions involving inflammation and thrombosis, or blood clotting.

1 Aug 2013

Brain development delay throughout childhood and adolescence for people born with FASD

Medical researchers at the University of Alberta recently published findings showing that brain development is delayed throughout childhood and adolescence for people born with Fetal Alcohol Spectrum Disorder (FASD).

1 Aug 2013

Medical Science News

Study discover two new mechanisms that govern editing in key neurodevelopmental gene

Using the immune system to control cancer: an interview with Dr. Jedd Wolchok, MD, PhD, Ludwig Center at MSKCC

'Dark matter' in human genome may play role in cancer biology and cell death

Novocure uses NovoTTF therapy to treat first recurrent glioblastoma tumor patient

Researchers theoretically create large, hollow magnetic cage molecules that could used in drug delivery system

Cambridge scientists identify molecular 'on/off' switch in malignant germ cell tumours

Researchers identify novel approach to enhance tissue repair and organ regeneration

Report suggests venom immunotherapy can make sufferers less allergic to insect stings

Scientists reveal biochemical pathway responsible for manufacturing glycoalkaloids

Scientists solve structure of infection tool used by Yersinia bacterium

Montreal scientists develop novel approach for scanning entire genome

Rheonix, Life Technologies sign joint development agreement for molecular testing platform

Oxytocin hormone affects men and women differently, research finds

Naked mole rat: A fitting model for finding novel ways to fight cancer

Transmembrane protein NG2 controls orientation of cell migration toward the wound

New approach could provide alternative treatment for chemotherapy-resistant breast cancer

Finding could influence effectiveness of bone marrow transplants for late-stage leukemia

Miniscule signaling molecule plays critical role in certain acute and chronic diseases

Novel protein could lead to development of new drugs to treat variety of cancers

Brain development delay throughout childhood and adolescence for people born with FASD

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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