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Study supports hypothesis that disulfiram reduces drug consumption by blocking DβH

Disulfiram was the first medication approved for the treatment of alcoholism over 50 years ago. It works, at least in part, by preventing the metabolism of an alcohol by-product, acetaldehyde. High levels of acetaldehyde in the body quickly cause unpleasant symptoms, including nausea, vomiting, headache, and accelerated heart rate. Thus, disulfiram provides a very strong incentive to avoid drinking.

1 Feb 2013

Study demonstrates new fragile genomic sites responsible for chromosomal alterations in tumors

Cancer arises from the accumulation of mutations and structural changes in chromosomes, which in some cases give rise to combinations that favour the growth or expansion of the disease. In this context, chromosomes tend to lose or duplicate entire regions, although, the mechanisms that initiate these chromosomal abnormalities are not fully understood.

1 Feb 2013

Study expands and deepens biological and genetic links between CVD and schizophrenia

A new study, to be published in the Feb. 7, 2013 issue of the American Journal of Human Genetics, expands and deepens the biological and genetic links between cardiovascular disease and schizophrenia. Cardiovascular disease (CVD) is the leading cause of premature death among schizophrenia patients, who die from heart and blood vessel disorders at a rate double that of persons without the mental disorder.

1 Feb 2013

SINEUP allows scientists to target individual genes in cells to increase protein production

One of the most innovative biotechnologies of the last decade has recently been developed. SINEUP allows scientists, for the first time, to target individual genes in cells to knockup, or increase, the amount of protein they make. The technique will improve Protein manufacture, analyse the function of genes and engineer improved cell function.

From Cell Guidance Systems 31 Jan 2013

Optofluidics to pre-launch Molecular NanoTweezer system in Feb. 2013

Optofluidics announces the pre-release of its Molecular NanoTweezer system - the most powerful optical trapping technology in the world - at SPIE Photonics West, BiOS and Biophysical Society annual meetings in Feb. 2013.

From Halo Labs 31 Jan 2013

Northeast Ohio Medical University, CEL-SCI produce new investigational breast cancer vaccine

CEL-SCI Corporation announced that its longstanding collaboration with Northeast Ohio Medical University has produced a new investigational breast cancer vaccine which prevents and treats a HER-2/neu expressing breast cancer tumor in a mouse model of the disease.

31 Jan 2013

Interferon retreatment of chronic hepatitis C may be harmful

People with hepatitis C and chronic liver disease who relapsed or failed to respond to initial treatment are unlikely to improve on interferon retreatment. In fact, they may face an increased risk of dying sooner, and are likely to experience a variety of adverse effects, according to an updated systematic review published in The Cochrane Library.

31 Jan 2013

Cerebrolysin: a promising new treatment for dementia

Dementia patients may benefit from a promising new treatment called Cerebrolysin, according to the results of a systematic review published in The Cochrane Library. The authors brought together the most up-to-date evidence on Cerebrolysin as a treatment for vascular dementia.

31 Jan 2013

Congenital sight impairment cure grows closer

A cure for congenital sight impairment caused by lens damage is closer following research by scientists at Monash University.

31 Jan 2013

C. albicans capable of sexual reproduction

Like many fungi and one-celled organisms, Candida albicans, a normally harmless microbe that can turn deadly, has long been thought to reproduce without sexual mating. But a new study by Professor Judith Berman and colleagues at the University of Minnesota and Tel Aviv University shows that C. albicans is capable of sexual reproduction.

31 Jan 2013

Review article highlights growing evidence for lasting impact of alcohol on the brain

Excessive alcohol use accounts for 4% of the global burden of disease, and binge drinking particularly is becoming an increasing health issue. A new review article published Cortex highlights the significant changes in brain function and structure that can be caused by alcohol misuse in young people.

31 Jan 2013

FET programme picks Graphene and HumanBrain among six visions for frontier research

Europe is set to embark on two bold, visionary projects. The projects aim to invest up to one billion euroover ten years to fuel revolutionary discoveries. The Future and Emerging Technologies Flagship (FET) programme picked two among six visions for frontier research.

31 Jan 2013

Study shows how gut microbes conspire with poor diets to trigger childhood malnutrition

A study of young twins in Malawi, in sub-Saharan Africa, finds that bacteria living in the intestine are an underlying cause of a form of severe acute childhood malnutrition.

31 Jan 2013

Scientists review damage-control in metabolism

In this week's issue of the prestigious journal Nature Chemical Biology, scientists Carole Linster (University of Luxembourg), Emile Van Schaftingen (Louvain University), and Andrew D. Hanson (University of Florida, Gainesville) review an important, but so far neglected, part of metabolism, namely metabolite damage-control.

31 Jan 2013

Binge drinking causes insulin resistance and increases risk of Type 2 diabetes

Binge drinking causes insulin resistance, which increases the risk of Type 2 diabetes, according to the results of an animal study led by researchers at the Diabetes Obesity and Metabolism Institute at the Icahn School of Medicine at Mount Sinai.

31 Jan 2013

Researchers identify mechanism by which vancomycin resistance spreads between bacteria

Worldwide, many strains of the bacterium Staphyloccocus aureus, commonly known as staph infections, are already resistant to all antibiotics except vancomycin. But as bacteria are becoming resistant to this once powerful antidote, S. aureus has moved one step closer to becoming an unstoppable killer.

31 Jan 2013

Enzymes may have new role as intelligent micro and nanomotors

Enzymes, workhorse molecules of life that underpin almost every biological process, may have a new role as "intelligent" micro- and nanomotors with applications in medicine, engineering and other fields.

31 Jan 2013

Silibinin kills skin cells mutated by UVA radiation and protects against cancer

A pair of University of Colorado Cancer Center studies published this month show that the milk thistle extract, silibinin, kills skin cells mutated by UVA radiation and protects against damage by UVB radiation - thus protecting against UV-induced skin cancer and photo-aging.

31 Jan 2013

New noninvasive method for early detection of osteoarthritis may be on its way

A new, noninvasive, and low-cost method for the early detection and monitoring of osteoarthritis (arthritis caused by wear and tear) may be on its way, thanks to research by UC Santa Barbara scientists from the Department of Chemical Engineering and the Department of Materials.

31 Jan 2013

Retired Jackson Laboratory scientist wins two major international science awards

Douglas Coleman, Ph.D., a retired Jackson Laboratory scientist whose work established the first clues to a genetic component in obesity, has won two major international science awards: the Frontiers of Knowledge Award in Biomedicine from the BBVA Foundation, based in Bilbao, Spain, and the King Faisal International Prize in Medicine from the Saudi Arabian King Faisal Foundation.

31 Jan 2013

Medical Science News

Study supports hypothesis that disulfiram reduces drug consumption by blocking DβH

Study demonstrates new fragile genomic sites responsible for chromosomal alterations in tumors

Study expands and deepens biological and genetic links between CVD and schizophrenia

SINEUP allows scientists to target individual genes in cells to increase protein production

Optofluidics to pre-launch Molecular NanoTweezer system in Feb. 2013

Northeast Ohio Medical University, CEL-SCI produce new investigational breast cancer vaccine

Interferon retreatment of chronic hepatitis C may be harmful

Cerebrolysin: a promising new treatment for dementia

Congenital sight impairment cure grows closer

C. albicans capable of sexual reproduction

Review article highlights growing evidence for lasting impact of alcohol on the brain

FET programme picks Graphene and HumanBrain among six visions for frontier research

Study shows how gut microbes conspire with poor diets to trigger childhood malnutrition

Scientists review damage-control in metabolism

Binge drinking causes insulin resistance and increases risk of Type 2 diabetes

Researchers identify mechanism by which vancomycin resistance spreads between bacteria

Enzymes may have new role as intelligent micro and nanomotors

Silibinin kills skin cells mutated by UVA radiation and protects against cancer

New noninvasive method for early detection of osteoarthritis may be on its way

Retired Jackson Laboratory scientist wins two major international science awards

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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