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Stem cell production becomes much easier with polymer-based 3D culture system

Mass producing human pluripotent stem cells (hPSCs), including embryonic stem cells and induced pluripotent stem cells, for regenerative medicine and drug discovery may have gotten much easier, thanks to a polymer-based 3D culture system developed by Japanese researchers.

26 Apr 2014

Johns Hopkins research may help manage the disruptive effects experienced by shift workers

Johns Hopkins researchers report that they have identified a protein essential to the formation of the tiny brain region in mice that coordinates sleep-wake cycles and other so-called circadian rhythms.

26 Apr 2014

Graphene may lead to new applications in the diagnosis and treatment of neurological diseases

The development of graphene-a highly advanced metamaterial with many unique and varied properties-may lead to exciting new applications in the diagnosis and treatment of neurological diseases, according to a report in the May issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

26 Apr 2014

Study could lead to better understanding of how Notch protein directs healthy development of organs

Johns Hopkins researchers report they have figured out how the aptly named protein Botch blocks the signaling protein called Notch, which helps regulate development. In a report on the discovery, to appear online April 24 in the journal Cell Reports, the scientists say they expect the work to lead to a better understanding of how a single protein, Notch, directs actions needed for the healthy development of organs as diverse as brains and kidneys.

26 Apr 2014

Findings shed light on evolution of mammalian behaviors and their brain mechanisms

A team led by scientists at The Scripps Research Institute has deciphered the surprisingly versatile code by which chemical cues help trigger some of the most basic behaviors in mice.

26 Apr 2014

Discovery offers potential target for reversing progression of end-stage liver disease

A team of researchers in the University of Arizona's College of Pharmacy has discovered a molecular pathway that could be key to creating new therapeutics that would slow or even reverse the progression of end-stage liver disease.

26 Apr 2014

MGH investigators develop next-generation genome editing system

A next-generation genome editing system developed by Massachusetts General Hospital investigators substantially decreases the risk of producing unwanted, off-target gene mutations. In a paper receiving online publication in Nature Biotechnology, the researchers report a new CRISPR-based RNA-guided nuclease technology that uses two guide RNAs, significantly reducing the chance of cutting through DNA strands at mismatched sites.

26 Apr 2014

Junk DNA linked to heart failure, reveals Washington University study

Large sections of the genome that were once referred to as "junk" DNA have been linked to human heart failure, according to research from Washington University School of Medicine in St. Louis.

26 Apr 2014

Study shows pro-inflammatory cytokine TNF-α can speed recovery in mouse with pulmonary fibrosis

Inflammation has long been considered an integral part of the biological process that leads to deadly scarring in idiopathic pulmonary fibrosis. New research at National Jewish Health, however, suggests that a little inflammation may also be crucial to the healing and repair processes in the lungs.

26 Apr 2014

Understanding biological underpinnings of source-memory impairment in humans

Indiana University neuroscientists Jonathon Crystal and Wesley Alford are zeroing in with increasing certainty on the notion that nonhuman animals have a particular type of memory known as "source memory," long seen as exclusively human.

26 Apr 2014

SFU researchers trace evolution of HIV in North America

A study tracing the evolution of HIV in North America involving researchers at Simon Fraser University has found evidence that the virus is slowly adapting over time to its human hosts. However, this change is so gradual that it is unlikely to have an impact on vaccine design.

26 Apr 2014

Promising new approach targets cancer protein to slow tumor growth

Sometimes a full-on assault isn't the best approach when dealing with a powerful enemy. A more effective approach, in the long run, may be to target the support system replenishing the supplies that keep your foe strong and ready for battle.

26 Apr 2014

French researchers introduce new method to effectively control bleeding and repair tissues

Stopping bleeding, closing wounds, repairing organs—these are everyday challenges in medical and surgical practice. In the journal Angewandte Chemie, French researchers have now introduced a new method that employs gluing by aqueous nanoparticle solutions to effectively control bleeding and repair tissues. In animal tests, their approach proved easy to apply, rapid and efficient even in situations when conventional methods are traumatic or fail.

25 Apr 2014

Effects of blueberry powder on blood pressure and arterial stiffness in postmenopausal women

Initial research out of Florida State University investigated whether daily consumption of a freeze-dried blueberry powder supplement resulted in a reduction of blood pressure and arterial stiffness, a measure of cardiovascular disease risk, in postmenopausal women with pre- and stage 1-hypertension.

25 Apr 2014

Researchers study likely effects of radiation on brain during deep space mission

Johns Hopkins scientists report that rats exposed to high-energy particles, simulating conditions astronauts would face on a long-term deep space mission, show lapses in attention and slower reaction times, even when the radiation exposure is in extremely low dose ranges.

25 Apr 2014

MIT researchers develop test that can rapidly assess DNA repair systems

Our DNA is under constant attack from many sources, including environmental pollutants, ultraviolet light, and radiation. Fortunately, cells have several major DNA repair systems that can fix this damage, which may lead to cancer and other diseases if not mended.

25 Apr 2014

Study: Functional electrical stimulation promotes neural cell proliferation in brains of rats with cerebral infarction

Previous studies have shown that proliferation of endogenous neural precursor cells cannot alone compensate for the damage to neurons and axons. From the perspective of neural plasticity, Dr. Yun Xiang and co-workers from Sun Yat-sen University in China observed the effects of functional electrical stimulation treatment on endogenous neural precursor cell proliferation and expression of basic fibroblast growth factor and epidermal growth factor in the rat brain on the infarct side.

25 Apr 2014

UB research finds novel compound for treating cocaine addiction

A novel compound that targets an important brain receptor has a dramatic effect against a host of cocaine addiction behaviors, including relapse behavior, a University at Buffalo animal study has found.

25 Apr 2014

Variant of cell surface protein may help develop drugs for gastric cancer

A team of scientists led by a researcher from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has identified the cancer specific stem cell which causes gastric cancer. This discovery opens up the possibility of developing new drugs for the treatment of this disease and other types of cancers.

25 Apr 2014

Prenatal smoking, genetic risk factors increase aggressive behavior in children

Researchers have found evidence of an interaction between prenatal smoking and genetic risk factors that increase aggressive behavior in children, especially in girls.

25 Apr 2014

Medical Science News

Stem cell production becomes much easier with polymer-based 3D culture system

Johns Hopkins research may help manage the disruptive effects experienced by shift workers

Graphene may lead to new applications in the diagnosis and treatment of neurological diseases

Study could lead to better understanding of how Notch protein directs healthy development of organs

Findings shed light on evolution of mammalian behaviors and their brain mechanisms

Discovery offers potential target for reversing progression of end-stage liver disease

MGH investigators develop next-generation genome editing system

Junk DNA linked to heart failure, reveals Washington University study

Study shows pro-inflammatory cytokine TNF-α can speed recovery in mouse with pulmonary fibrosis

Understanding biological underpinnings of source-memory impairment in humans

SFU researchers trace evolution of HIV in North America

Promising new approach targets cancer protein to slow tumor growth

French researchers introduce new method to effectively control bleeding and repair tissues

Effects of blueberry powder on blood pressure and arterial stiffness in postmenopausal women

Researchers study likely effects of radiation on brain during deep space mission

MIT researchers develop test that can rapidly assess DNA repair systems

Study: Functional electrical stimulation promotes neural cell proliferation in brains of rats with cerebral infarction

UB research finds novel compound for treating cocaine addiction

Variant of cell surface protein may help develop drugs for gastric cancer

Prenatal smoking, genetic risk factors increase aggressive behavior in children

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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