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Abide, Oxford partner to explore therapeutic potential of serine hydrolases

Abide Therapeutics announced today that the Company has entered into a collaborative agreement with the University of Oxford and the Oxford University Hospitals NHS Trust to explore the therapeutic potential of serine hydrolases, one of the largest enzyme classes with validated but under explored class of drug targets.

5 Nov 2014

UM researchers explain signaling systems that tissues use to communicate at the head-trunk region

Think about the way our bodies are assembled during early development and ask: How do neighboring cells know that they are supposed to become a nerve or a bone cell and how do these tissues find the correct place and alignment? Researchers at the University of Miami (UM) are answering these crucial questions.

5 Nov 2014

BYU study: Exposure to cigarette smoke can cause weight gain

New research is challenging the decades-old belief that smoking cigarettes helps keep you slim.

5 Nov 2014

Study suggests possible link between body fat and risk of immunotherapy toxicity

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found.

4 Nov 2014

Type 2 diabetes and cardiovascular disease share common risk factors

Type 2 diabetes (T2D) and cardiovascular disease (CVD) appear to have a lot in common. They share risk factors such as obesity and they often occur together. If they also share the same genetic underpinings, then doctors could devise a way to treat them together too.

4 Nov 2014

Researchers identify genetic markers that play role in alcoholism recovery

In an international study, Mayo Clinic researchers and collaborators have identified genetic markers that may help in identifying individuals who could benefit from the alcoholism treatment drug acamprosate. The findings, published in the journal Translational Psychiatry, show that patients carrying these genetic variants have longer periods of abstinence during the first three months of acamprosate treatment.

4 Nov 2014

Study reports IL-37's activity in the adaptive immune system

A University of Colorado Cancer Center study published in this month's Proceedings of the National Academy of Sciences describes the activity of a recently discovered communication molecule of the body's immune system, Interleukin 37 or IL-37. It has been known to limit inflammation and the current study reports its activity in the adaptive immune system: IL-37 inhibits the ability of the immune system to recognize and target new antigens.

4 Nov 2014

Scientists uncover small set of genes critical in aging and neurodegenerative disease

Aging is the most significant and universal risk factor for developing neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and Alzheimer's, Parkinson's and Huntington's diseases. This risk increases disproportionately with age, but no one really knows why.

4 Nov 2014

Study reveals impact of meditation, support groups at cellular level in breast cancer survivors

For the first time, researchers have shown that practising mindfulness meditation or being involved in a support group has a positive physical impact at the cellular level in breast cancer survivors.

4 Nov 2014

Cellular-level changes in nerve structure and function may contribute to migraine headaches

A new study shows cellular-level changes in nerve structure and function that may contribute to the development of migraine headaches, reports the November issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS).

4 Nov 2014

NSAIDs protect against colorectal cancer by inducing cell suicide pathways in intestinal stem cells

Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) protect against the development of colorectal cancer by inducing cell suicide pathways in intestinal stem cells that carry a certain mutated and dysfunctional gene, according to a new study led by researchers at the University of Pittsburgh Cancer Institute and the School of Medicine.

4 Nov 2014

MO BIO Laboratories announces launch of PowerMag Blood DNA/RNA Isolation Kit

MO BIO Laboratories, Inc., the leader in soil, stool and microbial nucleic acid purification, announces the launch of the PowerMag Blood DNA/RNA Isolation Kit. The kit is designed for automated, hands-free purification of nucleic acids from blood samples using the Thermo Scientific KingFisher automated processing system and other similar automation platforms.

4 Nov 2014

Douglas Mental Health University Institute researcher wins 2014 Wilder-Penfield prize

The Douglas Mental Health University Institute is proud to announce that its researcher and neurobiologist, Michael Meaney, C.M., Ph.D., C.Q., FRSC, is the 2014 laureate of the prestigious prix Wilder-Penfield.

4 Nov 2014

AbbVie and Myriad Genetics expand Tumor BRACAnalysis CDx collaboration

Myriad Genetics, Inc. announced today that it has signed an expanded companion diagnostic agreement with AbbVie, Inc., a leading global biopharmaceutical company to use Tumor BRACAnalysis CDx™ as a companion diagnostic in support of AbbVie’s novel poly (ADP-ribose) polymerase or PARP inhibitor, veliparib.

4 Nov 2014

Astellas, Dana-Farber to develop K-Ras inhibitors for treatment of lung, pancreatic cancers

Dana-Farber Cancer Institute (Dana-Farber) and Astellas Pharma Inc. today announced a three-year collaboration to research and develop small molecule inhibitors of oncogenic K-Ras for the treatment of cancer, including lung cancer.

4 Nov 2014

3D brain-like tissue: an interview with Professor David Kaplan, Tufts University

In 2D, neurons tend to form limited connectivity reflective of the 3D complexity in the brain and have more limited cultivation time before reduction in functions.

4 Nov 2014

EBioMedicine: Open access journal from Elsevier

Elsevier is a world-leading provider of scientific, technical and medical information products and services. Two of its leading brands, Cell Press and The Lancet, have now joined forces to launch a new open access journal, EBioMedicine.

4 Nov 2014

Researchers identify potential therapeutic target for glioblastoma

A multicenter team of researchers has identified an enzyme key to the survival and spread of glioblastoma cancer cells that is not present in healthy brain cells, making the enzyme a promising therapeutic target.

4 Nov 2014

Advanced Cell Diagnostics names Aquila-Histoplex as the first accredited RNAscope® Certified Service Provider in Europe

Aquila-Histoplex, a contract research organisation specialised in histological and multiplex staining technologies, was today announced as the first accredited RNAscope® Certified Service Provider in Europe by Advanced Cell Diagnostics, Inc. (ACD), a technology and market leader in the field of molecular pathology and developer of cell and tissue-based analysis tools.

From Advanced Cell Diagnostics 4 Nov 2014

Innovative tool could redefine limits of synthetic biology, improve study of yeast genetics

NYU Langone yeast geneticists report they have developed a novel tool -- dubbed "the telomerator" -- that could redefine the limits of synthetic biology and advance how successfully living things can be engineered or constructed in the laboratory based on an organism's genetic, chemical base-pair structure.

4 Nov 2014

Medical Science News

Abide, Oxford partner to explore therapeutic potential of serine hydrolases

UM researchers explain signaling systems that tissues use to communicate at the head-trunk region

BYU study: Exposure to cigarette smoke can cause weight gain

Study suggests possible link between body fat and risk of immunotherapy toxicity

Type 2 diabetes and cardiovascular disease share common risk factors

Researchers identify genetic markers that play role in alcoholism recovery

Study reports IL-37's activity in the adaptive immune system

Scientists uncover small set of genes critical in aging and neurodegenerative disease

Study reveals impact of meditation, support groups at cellular level in breast cancer survivors

Cellular-level changes in nerve structure and function may contribute to migraine headaches

NSAIDs protect against colorectal cancer by inducing cell suicide pathways in intestinal stem cells

MO BIO Laboratories announces launch of PowerMag Blood DNA/RNA Isolation Kit

Douglas Mental Health University Institute researcher wins 2014 Wilder-Penfield prize

AbbVie and Myriad Genetics expand Tumor BRACAnalysis CDx collaboration

Astellas, Dana-Farber to develop K-Ras inhibitors for treatment of lung, pancreatic cancers

3D brain-like tissue: an interview with Professor David Kaplan, Tufts University

EBioMedicine: Open access journal from Elsevier

Researchers identify potential therapeutic target for glioblastoma

Advanced Cell Diagnostics names Aquila-Histoplex as the first accredited RNAscope® Certified Service Provider in Europe

Innovative tool could redefine limits of synthetic biology, improve study of yeast genetics

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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