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Children with changes in bully genes have poor survival

In a genome sequencing study of 74 neuroblastoma tumors in children, scientists at the Johns Hopkins Kimmel Cancer Center and the Children's Hospital of Philadelphia (CHOP) found that patients with changes in two genes, ARID1A and ARID1B, survive only a quarter as long as patients without the changes. The discovery could eventually lead to early identification of patients with aggressive neuroblastomas who may need additional treatments.

3 Dec 2012

Scientists discover how humans and mammals develop intelligence

Scientists have discovered for the first time how humans - and other mammals - have evolved to have intelligence.

3 Dec 2012

Chronic focal brain cooling suppresses seizures during wakefulness

Neuroscientists from Japan's Yamaguchi University today reported during the 66th annual scientific meeting of the American Epilepsy Society (AES) that chronic focal brain cooling suppresses seizures during wakefulness and achieves the effect without significantly affecting brain function. Their research, and that of others in the field, provides critical evidence that this approach to seizure control has reached a stage where testing in humans will soon be possible.

3 Dec 2012

Long-term hippocampal DBS effectively reduces seizures in experimental models

The results of the first reported study of deep brain stimulation (DBS) in an animal model for temporal lobe epilepsy (TLE) presented today at the American Epilepsy Society (AES) 66th Annual Meeting suggests that DBS may have potential as therapy for this common and often difficult to treat form of epilepsy.

2 Dec 2012

TINCR molecule plays a master role in epidermal differentiation

The surface of your skin, called the epidermis, is a complex mixture of many different cell types - each with a very specific job. The production, or differentiation, of such a sophisticated tissue requires an immense amount of coordination at the cellular level, and glitches in the process can have disastrous consequences. Now, researchers at the Stanford University School of Medicine have identified a master regulator of this differentiation process.

2 Dec 2012

Scientists demonstrate how glowing fish can help screen drugs that control metabolic disorders

A tiny, translucent zebrafish that glows green when its liver makes glucose has helped an international team of researchers identify a compound that regulates whole-body metabolism and appears to protect obese mice from signs of metabolic disorders.

2 Dec 2012

Scientists determine how two proteins help create organelles

Scientists at The Scripps Research Institute (TSRI) have determined how two proteins help create organelles, or specialized subunits within a cell, that play a vital role in maintaining cell health. This discovery opens the door for research on substances that could interfere with the formation of these organelles and lead to new therapies for cancer.

2 Dec 2012

Low-level exposure to organophosphates affects neurological and cognitive function

Scientists have found that low-level exposure to organophosphates (OPs) produces lasting decrements in neurological and cognitive function. Memory and information processing speed are affected to a greater degree than other cognitive functions such as language.

2 Dec 2012

Scientists sequence DNA of biopsied tissue from colon polyps

The causes underlying the development of certain types of common cancers have not yet been elucidated. In order to better determine the origin and the sequence of events responsible for the onset of colon cancer, the teams led by Thanos Halazonetis and Stylianos Antonarakis, professors at the University of Geneva (UNIGE), Switzerland, have sequenced the DNA of biopsied tissue from colon polyps.

2 Dec 2012

Researchers to fortify milk with heart healthy omega-3 fatty acids

Not everyone has a taste for fish, even though it is a natural source of heart-healthy omega-3 fatty acids. And while a growing number of omega-3 enriched foods may net health benefits for people who resist the lure of salmon or sashimi, milk remains the product that has gotten away in what has become a billion-dollar health industry.

1 Dec 2012

Study examines role of inflammation in chronic fatigue syndrome

A new study published in the current issue of Psychotherapy and Psychosomatics has examined the role of inflammation in chronic fatigue syndrome, a disorder that affects many people and does not seem to have an explanation that is likely to yield satisfactory treatment.

1 Dec 2012

Researchers find association between neuroscience providers and stroke-related deaths in US

Researchers at Dartmouth-Hitchcock Medical Center in Lebanon, New Hampshire, have found an association in the United States between a higher density of neurologists and neurosurgeons and a decreased risk of death from stroke.

1 Dec 2012

Researchers uncover molecular structure of master regulator central to melanoma

With the X-ray vision of DESY's light source DORIS, a research team from Hamburg and Iceland has uncovered the molecular structure of a master regulator central to the most deadly form of skin cancer, melanoma.

1 Dec 2012

Brain study provides new insights into how recognition is connected with emotion and morality

People are able to detect, within a split second, if a hurtful action they are witnessing is intentional or accidental, new research on the brain at the University of Chicago shows.

1 Dec 2012

Loss of either T-bet or Eomes protein reduces immune system's ability to fight viral infection

When you get an acute infection, such as influenza, the body generally responds with a coordinated response of immune-cell proliferation and attack that rapidly clears the pathogen. Then, their mission done, the immune system stands down, leaving a population of sentinel memory cells to rapidly redeploy the immune system in the event of reinfection.

1 Dec 2012

Scientists can produce new proteins by following certain rules

By following certain rules, scientists can prepare architectural plans for building ideal protein molecules not found in the real world. Based on these computer renditions, previously non-existent proteins can be produced from scratch in the lab. The principles to make this happen appear this month in Nature magazine.

1 Dec 2012

New genetic study defines biology behind brain developmental disorder in children

This study describes how a combination of sequencing and mouse models were used to identify the gene responsible for a brain developmental disorder seen in four patients.

1 Dec 2012

Researchers study antimicrobial peptides in fish gills to find solution for blocking human infections

Living in an environment teaming with bacteria and fungi, fish have evolved powerful defenses against waterborne pathogens, including antimicrobial peptides located in their gills. Undergraduate researchers at Worcester Polytechnic Institute are studying the biology and the mechanics of one of those peptides with the hope they can use that knowledge to create engineered surfaces that kill bacteria responsible for foodborne illnesses and hospital-acquired infections.

1 Dec 2012

New study on mice could open door to methods of regulating cell proliferation in humans

A newly-engineered strain of mice whose dividing cells express a fluorescent protein could open the door to new methods of regulating cell proliferation in humans.

1 Dec 2012

Tissue damage, disease severity in C. diff. infection associated with disruption of PPARγ pathway

Researchers in the Nutritional Immunology and Molecular Medicine Laboratory at Virginia Bioinformatics Institute have discovered how a common diarrhea-causing bacterium sends the body's natural defenses into overdrive, actually intensifying illness while fighting infection.

1 Dec 2012

Medical Science News

Children with changes in bully genes have poor survival

Scientists discover how humans and mammals develop intelligence

Chronic focal brain cooling suppresses seizures during wakefulness

Long-term hippocampal DBS effectively reduces seizures in experimental models

TINCR molecule plays a master role in epidermal differentiation

Scientists demonstrate how glowing fish can help screen drugs that control metabolic disorders

Scientists determine how two proteins help create organelles

Low-level exposure to organophosphates affects neurological and cognitive function

Scientists sequence DNA of biopsied tissue from colon polyps

Researchers to fortify milk with heart healthy omega-3 fatty acids

Study examines role of inflammation in chronic fatigue syndrome

Researchers find association between neuroscience providers and stroke-related deaths in US

Researchers uncover molecular structure of master regulator central to melanoma

Brain study provides new insights into how recognition is connected with emotion and morality

Loss of either T-bet or Eomes protein reduces immune system's ability to fight viral infection

Scientists can produce new proteins by following certain rules

New genetic study defines biology behind brain developmental disorder in children

Researchers study antimicrobial peptides in fish gills to find solution for blocking human infections

New study on mice could open door to methods of regulating cell proliferation in humans

Tissue damage, disease severity in C. diff. infection associated with disruption of PPARγ pathway

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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