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Scientists unravel the major cause of protein citrullination in rheumatoid arthritis

Experiments by scientists at Johns Hopkins and in Boston have unraveled two biological mechanisms as the major cause of protein citrullination in rheumatoid arthritis. Protein citrullination is suspected of sparking the immune system and driving the cascade of events leading to the disease.

31 Oct 2013

EcoHealth Alliance discovers new SARS-like coronavirus in Chinese horseshoe bats

EcoHealth Alliance, a nonprofit organization that focuses on local conservation and global health issues, announced the discovery of a new SARS-like coronavirus (CoV) in Chinese horseshoe bats.

31 Oct 2013

Researchers highlight presence of specific antibodies that regulate appetite in obese patients

Obesity affects more than 15% of adults in France, and its constitutive mechanisms are still not completely explained. Normally, fine control of weight and food intake is coordinated by a specialised part of the brain (the hypothalamus).

31 Oct 2013

RI-MUHC researchers identify genetic changes that could pave way for early diagnosis of CRC

Diagnosing colorectal cancer is complex; it relies on significant invasive tests and subjective evaluations. This process may soon become much easier thanks to a medical breakthrough by scientists at the Research Institute of the McGill University Health Centre.

31 Oct 2013

Scientists develop new therapeutic approach for treatment of type 2 diabetes

Scientists from the Helmholtz Zentrum Muenchen and the Technische Universitaet Muenchen, together with scientists in the USA, have developed a new therapeutic approach for treatment of Type 2 diabetes. A novel single molecule hormone, which acts equally on the receptors of the insulin-stimulating hormones GLP-1 and GIP, was observed to reduce weight and improve blood sugar.

31 Oct 2013

Black women with vitamin D deficiency during pregnancy more likely to deliver preterm babies

African-American and Puerto Rican women who have low levels of vitamin D during pregnancy are more likely to go into labor early and give birth to preterm babies, research led by the University of Pittsburgh Graduate School of Public Health reveals.

31 Oct 2013

Honey may be detrimental for patients with type 2 diabetes

Honey may be detrimental for patients with type 2 diabetes because of the great quantities of sugars it contains.

31 Oct 2013

UofL researcher enters into license and research collaboration agreement with Novartis

The University of Louisville today announced that researcher Dr. Suzanne Ildstad, representing Regenerex LLC, has entered into a license and research collaboration agreement with Novartis to provide access to stem cell technology that has the potential to help transplant patients avoid taking anti-rejection medicine for life and could serve as a platform for treatment of other diseases.

31 Oct 2013

Reduced SMG1 protein expression may contribute to neurological disorders

The absence of a protein called SMG1 could be a contributing factor in the development of Parkinson's disease and other related neurological disorders, according to a study led by the Translational Genomics Research Institute.

31 Oct 2013

Brain-derived neurotrophic factor may inhibit glucose intolerance after cerebral ischemia

Interestingly, a recent study found that ischemic stress causes hyperglycemia and may worsen ischemic neuronal damage. In addition, decreased insulin sensitivity after ischemic stress seems to be involved in the development of post-ischemic glucose intolerance.

30 Oct 2013

HDL-like particles could someday be used to combat atherosclerosis

A new type of "good cholesterol," made in the lab, could one day deliver drugs to where they are needed in the body to treat disease or be used in medical imaging, according to scientists.

30 Oct 2013

Study suggests neural stem cells have tendency for malignant transformation

Although it is believed that glioma is derived from brain tumor stem cells, the source and molecular signal pathways of these cells are still unclear.

30 Oct 2013

Genetic factors may be the same for specific language impairment and language-impaired autism

In the first molecular genetic study of families with a history of both language impairment and autism, scientists may have uncovered a shared origin for the two conditions, an important step toward explaining why some cases of autism are accompanied by language difficulties and others are not. The study, a collaboration of The Research Institute at Nationwide Children's Hospital with experts at Rutgers University, indicates that a disorder called specific language impairment—one of the most common developmental delays in children—may be caused by the same genetic variants that lead to language difficulties in some children with autism.

30 Oct 2013

Researchers overcome obstacle to using viruses to deliver therapeutic genes

Scientists in The Research Institute at Nationwide Children's Hospital have found a way to overcome one of the biggest obstacles to using viruses to deliver therapeutic genes: how to keep the immune system from neutralizing the virus before it can deliver its genetic payload. In a study published recently in Molecular Therapy, researchers found that giving subjects a treatment to temporarily rid the body of antibodies provides the virus safe passage to targeted cells, allowing it to release a corrective or replacement gene to treat disease.

30 Oct 2013

Meta-analysis shows that XRCC1 Arg399Gln polymorphism may be a biomarker of glioma susceptibility

DNA damage is an important mechanism of glioma. X-ray cross-complementing group 1 (XRCC1) is a DNA repair gene that participates in the base excision repair pathway. To date, many studies have been performed to investigate the association between the XRCC1 polymorphisms and risk of cancers such as breast cancer, and gastroesophageal cancer, but the number of studies that focused on glioma is relatively small.

30 Oct 2013

Medical Science News

Scientists unravel the major cause of protein citrullination in rheumatoid arthritis

EcoHealth Alliance discovers new SARS-like coronavirus in Chinese horseshoe bats

Researchers highlight presence of specific antibodies that regulate appetite in obese patients

RI-MUHC researchers identify genetic changes that could pave way for early diagnosis of CRC

Scientists develop new therapeutic approach for treatment of type 2 diabetes

Black women with vitamin D deficiency during pregnancy more likely to deliver preterm babies

Honey may be detrimental for patients with type 2 diabetes

UofL researcher enters into license and research collaboration agreement with Novartis

Reduced SMG1 protein expression may contribute to neurological disorders

Brain-derived neurotrophic factor may inhibit glucose intolerance after cerebral ischemia

HDL-like particles could someday be used to combat atherosclerosis

Study suggests neural stem cells have tendency for malignant transformation

Genetic factors may be the same for specific language impairment and language-impaired autism

Researchers overcome obstacle to using viruses to deliver therapeutic genes

Meta-analysis shows that XRCC1 Arg399Gln polymorphism may be a biomarker of glioma susceptibility

New DNA vaccine effective against plaques in mouse model of Alzheimer's disease

Research provides better understanding of molecular interactions related to cystic fibrosis

Video gaming increases spatial orientation, memory formation and motor skills

Eyetrack study maps visual behavior of both men and women

Mice exploit IRG proteins to create resistance mechanism against toxoplasma infection

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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