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BMH-21 chemical compound has ability to shut down a common cancer process

Johns Hopkins scientists say a previously known but little studied chemical compound targets and shuts down a common cancer process. In studies of laboratory-grown human tumor cell lines, the drug disrupted tumor cell division and prevented growth of advanced cancer cells.

15 Jan 2014

Cedars-Sinai investigators identify new molecular abnormalities in diabetic cornea

Investigators at the Cedars-Sinai Regenerative Medicine Institute have identified new molecular abnormalities in the diabetic cornea that could contribute to eye problems in affected patients. With this new knowledge, investigators aim to accelerate the process of healing and repair in damaged corneas to ultimately reverse the effects of diabetes-induced eye complications.

15 Jan 2014

New gold nanoparticle method allows for tracking studies of virus pathways in tissues

Enteroviruses are pathogenic viruses infecting humans. This group consists of polioviruses, coxsackieviruses, echoviruses and rhinoviruses. Enteroviruses are the most common causes of flu, but they also cause serious symptoms such as heart muscle infections and paralysis. Recently, enteroviruses have been linked with chronic diseases such as diabetes.

15 Jan 2014

Breast cancer cells masquerade as neurons begin to form ultimately-deadly brain tumors

Treatment and "cure" of breast cancer doesn't ensure that the disease won't spread to the brain. Too often, sometimes years after an initial diagnosis and remission, breast cancer cells are discovered growing as new tumors within the brain. Now City of Hope researchers have found how this happens.

15 Jan 2014

Researchers look at age-related differences on how memories are stored and retrieved

It's not that younger people are able to remember more than older people. Their memories seem better because they are able to retrieve them in higher definition. So says Philip Ko of Vanderbilt University in the US, in a study that sheds light on how differences in the behavioral and neural activity of younger and older adults influence the different generations' ability to store and recall memories.

15 Jan 2014

New system allows us to power our devices long after sun goes down

Solar energy has long been used as a clean alternative to fossil fuels such as coal and oil, but it could only be harnessed during the day when the sun's rays were strongest. Now researchers led by Tom Meyer at the Energy Frontier Research Center at the University of North Carolina at Chapel Hill have built a system that converts the sun's energy not into electricity but hydrogen fuel and stores it for later use, allowing us to power our devices long after the sun goes down.

15 Jan 2014

Less gray matter in brain not linked to reading disabilities in people with dyslexia

In people with dyslexia, less gray matter in the brain has been linked to reading disabilities, but now new evidence suggests this is a consequence of poorer reading experiences and not the root cause of the disorder.

15 Jan 2014

Research paper highlights the role of T-cells in HIV

Ryan Zurakowski, assistant professor of electrical and computer engineering at the University of Delaware, is co-author of a paper appearing in Nature Medicine on Jan. 12 highlighting the role of T-cells in HIV.

15 Jan 2014

Presence of gene variant in people with MCI associated with accelerated rates of brain atrophy

The presence of a gene variant in people with mild cognitive impairment is associated with accelerated rates of brain atrophy, according to a new study published online in the journal Radiology.

15 Jan 2014

Research reveals new therapy for preventing production of sphingolipids by lymphoma cells

Christopher Parsons, MD, Director of the HIV Malignancies Program at LSU Health Sciences Center New Orleans, is the senior author of a paper that is the first to report that specialized fat (lipid) molecules, called sphingolipids, play a key role in the survival of aggressive lymphomas caused by viruses.

15 Jan 2014

Brain's structure is related to how intensely people perceive pain, say scientists

Everybody feels pain differently, and brain structure may hold the clue to these differences. In a study published in the current online issue of the journal Pain, scientists at Wake Forest Baptist Medical Center have shown that the brain's structure is related to how intensely people perceive pain.

15 Jan 2014

High concentrations of serum omega-3 fatty acids may help reduce risk of type 2 diabetes

High concentrations of serum long-chain omega-3 fatty acids may help reduce the risk of type 2 diabetes, according to a University of Eastern Finland study published recently in Diabetes Care. The sources of these fatty acids are fish and fish oils.

14 Jan 2014

At-home paper test can help spot early symptoms of cognitive issues

The Self-Administered Gerocognitive Examination (SAGE test), which takes less than 15 minutes to complete, is a reliable tool for evaluating cognitive abilities. Findings by researchers at The Ohio State University Wexner Medical Center confirming the feasibility and efficiency of the tool for community screening large numbers of people are published in the January issue of The Journal of Neuropsychiatry and Clinical Neurosciences.

13 Jan 2014

UMMS researchers commissioned by Alpha-1 Project to develop PiZ antibody

Researchers at the University of Massachusetts Medical School (UMMS) have been commissioned by the Alpha-1 Project (TAP) to develop a PiZ antibody. The antibody will be used to track the presence of mutant alpha-1 PiZ protein in human blood serum, an essential tool in testing potential therapies for Alpha-1 Antitrypsin Deficiency (Alpha-1).

13 Jan 2014

Scientists progress towards understanding how some bacterial cells escape being killed by antibiotics

Scientists have made an important advance in understanding how a subset of bacterial cells escape being killed by many antibiotics.

10 Jan 2014

Patient's own bone-marrow stromal cells could treat multi-drug resistant TB

Findings of a preliminary study published in The Lancet Respiratory Medicine suggest that a patient’s own bone-marrow stromal (stem) cells could be used to treat multidrug-resistant (MDR) and extensively-drug (XDR) tuberculosis.

10 Jan 2014

Study shows wide-ranging variation in patterns of X chromosome inactivation in female mice

Producing brightly speckled red and green snapshots of many different tissues, Johns Hopkins researchers have color-coded cells in female mice to display which of their two X chromosomes has been made inactive, or “silenced.”

10 Jan 2014

New technology efficiently transfers investigational antibodies from blood via blood-brain barrier

Today the scientific journal Neuron published results on the Roche-designed Brain Shuttle technology that efficiently transfers investigational antibodies from the blood through the blood-brain barrier (BBB) into the brain in preclinical models.

10 Jan 2014

Hormone associated with improved glucose metabolism activates calorie-burning brown fat

Researchers at Joslin Diabetes Center have discovered that a hormone long associated with weight loss and improved glucose metabolism is linked to activation of calorie-burning brown fat.

10 Jan 2014

Foundation Medicine announces discovery of high incidence of ERBB2 alterations in MPUC patients

Foundation Medicine, Inc. today announced the discovery of a high incidence of ERBB2 (HER2) extracellular domain alterations in patients with micropapillary urothelial carcinoma, a particularly aggressive form of urinary bladder cancer, using FoundationOne. The research was published in the current edition of Clinical Cancer Research.

10 Jan 2014

Medical Science News

BMH-21 chemical compound has ability to shut down a common cancer process

Cedars-Sinai investigators identify new molecular abnormalities in diabetic cornea

New gold nanoparticle method allows for tracking studies of virus pathways in tissues

Breast cancer cells masquerade as neurons begin to form ultimately-deadly brain tumors

Researchers look at age-related differences on how memories are stored and retrieved

New system allows us to power our devices long after sun goes down

Less gray matter in brain not linked to reading disabilities in people with dyslexia

Research paper highlights the role of T-cells in HIV

Presence of gene variant in people with MCI associated with accelerated rates of brain atrophy

Research reveals new therapy for preventing production of sphingolipids by lymphoma cells

Brain's structure is related to how intensely people perceive pain, say scientists

High concentrations of serum omega-3 fatty acids may help reduce risk of type 2 diabetes

At-home paper test can help spot early symptoms of cognitive issues

UMMS researchers commissioned by Alpha-1 Project to develop PiZ antibody

Scientists progress towards understanding how some bacterial cells escape being killed by antibiotics

Patient's own bone-marrow stromal cells could treat multi-drug resistant TB

Study shows wide-ranging variation in patterns of X chromosome inactivation in female mice

New technology efficiently transfers investigational antibodies from blood via blood-brain barrier

Hormone associated with improved glucose metabolism activates calorie-burning brown fat

Foundation Medicine announces discovery of high incidence of ERBB2 alterations in MPUC patients

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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