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NGM, MedImmune partner to develop novel therapeutics for treatment of diabetes and obesity

NGM Biopharmaceuticals, Inc. and MedImmune, the global biologics research and development arm of AstraZeneca, announced today that they have entered into an exclusive agreement to discover, develop and commercialize novel therapeutics from NGM's enteroendocrine cell program for the treatment of type 2 diabetes and obesity.

17 Jun 2013

Researchers produce first genome-wide investigation of cap-independent translation

Because of their central importance to biology, proteins have been the focus of intense research, particularly the manner in which they are produced from genetically coded templates-a process commonly known as translation. While the general mechanism of translation has been understood for some time, protein synthesis can initiate by more than one mechanism. One of the least well understood mechanisms is known as cap-independent translation.

17 Jun 2013

Athera receives support from FP7 for development of fully human antibody PC-mAb

Athera Biotechnologies AB today announced that future development costs of its fully human antibody PC-mAb up until proof-of-concept will be co-funded by the European Union's Seventh Framework Programme for Research (FP7) through a collaborative research grant. Karolinska Development AB owns 65% of Athera Biotechnologies AB.

17 Jun 2013

Scientists find that psychiatric disorders may be linked to protein involved in memory formation

Researchers have discovered a pathway by which the brain controls a molecule critical to forming long-term memories and connected with bipolar disorder and schizophrenia.

17 Jun 2013

Researchers identify genetic mutation responsible for MDP Syndrome

National Paracycling Champion Tom Staniford has an extremely rare condition which, until now, has puzzled his doctors. He is unable to store fat under his skin - yet has type 2 diabetes - and suffered hearing loss as a child. Now, thanks to advances in genome sequencing, an international research team led by the University of Exeter Medical School has identified Tom's condition and pinpointed the single genetic mutation that causes it.

17 Jun 2013

Scientists develop new tool for analyzing and characterizing aspects of the brain's neural circuitry

Scientists at the University of Massachusetts Medical School have developed a novel transgenic system which allows them to remotely activate individual brain cells in the model organism Drosophila using ambient temperature.

17 Jun 2013

New research reports that UnaG protein could lead to new liver test

Many scientists dream of making a single discovery that provides fundamental insight into nature, may be used to help save human lives, and can assist in the preservation of an endangered species. In new research reported in the journal Cell, a Japanese team is on the verge of accomplishing this nearly impossible feat.

17 Jun 2013

Study shows how cancer cells interact with healthy cells to migrate around the body during metastasis

A mechanism that cells use to group together and move around the body - called 'chase and run' - has been described for the first time by scientists at UCL.

17 Jun 2013

Pathway Genomics to provide genetic testing for BRCA gene linked to breast, ovarian cancers

Pathway Genomics led the evening news Friday with an announcement that it could begin offering affordable access to genetic testing for the BRCA gene linked to breast and ovarian cancers in the wake of a Supreme Court ruling that eliminated another company's monopoly on the test.

15 Jun 2013

NPS Pharmaceuticals president receives Ernst & Young Entrepreneur Award in Life Sciences category

NPS Pharmaceuticals, Inc. (NASDAQ: NPSP), a biopharmaceutical company pioneering and delivering therapies that transform the lives of patients with rare diseases worldwide, today announced that president and chief executive officer Francois Nader, M.D. has received the Ernst & Young Entrepreneur Of The Year® 2013 Award in the Life Sciences category in New Jersey. Dr. Nader was presented with the award at a special gala event on June 13 at the Hyatt Regency New Brunswick, New Jersey.

15 Jun 2013

Study shows patients with avascular necrosis have turned to stem cell therapy for aid

Stem cells have long been touted as the next big thing. Well just maybe, it is here. According to Dr. Dennis Lox, some patients with a disorder of the bone called avascular necrosis (AVN), have turned to stem cell therapy for aid.

15 Jun 2013

In unanimous decision, Supreme Court justices rule genes can't be patented

The decision was applauded by many researchers and drew speculation that it could likely boost patient care. Meanwhile, the stock of Myriad Genetics tumbled after the court's finding invalidated the company's hold on testing for two breast cancer genes.

15 Jun 2013

Comparison of 1,000-year-old and modern bacterial genomes provides insights into history of leprosy pathogen

From skeletons and biopsies, an international team of scientists was successful in reconstructing a dozen medieval and modern genomes of the leprosy-causing bacteria Mycobacterium leprae.

15 Jun 2013

Penn researchers develop variant of mu opioid painkiller receptor to overcome side effects

Opioids, such as morphine, are still the most effective class of painkillers, but they come with unwanted side effects and can also be addictive and deadly at high doses. Designing new pain-killing drugs of this type involves testing them on their corresponding receptors, but access to meaningful quantities of these receptors that can work in experimental conditions has always been a limiting factor.

15 Jun 2013

Researchers uncover DNA damage checkpoint used by cells to monitor oxidatively damaged DNA

In current health lore, antioxidants are all the rage, as "everybody knows" that reducing the amount of "reactive oxygen species" -- cell-damaging molecules that are byproducts of cellular metabolism -- is critical to staying healthy. What everyone doesn't know is that our bodies already have a complex set of processes built into our cells that handle these harmful byproducts of living and repair the damage they cause.

15 Jun 2013

HandsFree system helps analyze next generation sequencing data

In the early 1990s, an international effort was launched by the U.S. Department of Energy and the National Institutes of Health to sequence the human genome. The project took 13 years, involved many scientists in several countries, and cost $2.7 billion (in FY 1991) dollars.

15 Jun 2013

UCSF researchers discover memory-boosting molecule in mice

Memory improved in mice injected with a small, drug-like molecule discovered by UCSF San Francisco researchers studying how cells respond to biological stress.

15 Jun 2013

New research finding raises questions about common mutant forms of JC polyomavirus

The JC polyomavirus is clearly opportunistic. It infects half the population but lethally destroys brain tissue only in immunocompromised patients - and it may be outright sneaky, too. Even as a new research paper allays fears that common mutant forms of the virus are the ones directly responsible for the disease's main attack, that same finding raises new questions about what the mutants are doing instead.

14 Jun 2013

Researchers are one step closer to treating type 1 diabetes

Researchers at Washington University School of Medicine in St. Louis have identified a way to trigger reproduction in the laboratory of clusters of human cells that make insulin, potentially removing a significant obstacle to transplanting the cells as a treatment for patients with type 1 diabetes.

14 Jun 2013

Study: Shiga toxin-producing E. coli survive longer in recreational water, can prove dangerous to humans

A toxin dangerous to humans may help E. coli fend off aquatic predators, enabling strains of E. coli that produce the toxin to survive longer in lake water than benign counterparts, a new study finds.

14 Jun 2013

Medical Science News

NGM, MedImmune partner to develop novel therapeutics for treatment of diabetes and obesity

Researchers produce first genome-wide investigation of cap-independent translation

Athera receives support from FP7 for development of fully human antibody PC-mAb

Scientists find that psychiatric disorders may be linked to protein involved in memory formation

Researchers identify genetic mutation responsible for MDP Syndrome

Scientists develop new tool for analyzing and characterizing aspects of the brain's neural circuitry

New research reports that UnaG protein could lead to new liver test

Study shows how cancer cells interact with healthy cells to migrate around the body during metastasis

Pathway Genomics to provide genetic testing for BRCA gene linked to breast, ovarian cancers

NPS Pharmaceuticals president receives Ernst & Young Entrepreneur Award in Life Sciences category

Study shows patients with avascular necrosis have turned to stem cell therapy for aid

In unanimous decision, Supreme Court justices rule genes can't be patented

Comparison of 1,000-year-old and modern bacterial genomes provides insights into history of leprosy pathogen

Penn researchers develop variant of mu opioid painkiller receptor to overcome side effects

Researchers uncover DNA damage checkpoint used by cells to monitor oxidatively damaged DNA

HandsFree system helps analyze next generation sequencing data

UCSF researchers discover memory-boosting molecule in mice

New research finding raises questions about common mutant forms of JC polyomavirus

Researchers are one step closer to treating type 1 diabetes

Study: Shiga toxin-producing E. coli survive longer in recreational water, can prove dangerous to humans

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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