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Severe RSV disease may impair innate immune response in infants

Infants with severe lower respiratory tract infection caused by respiratory syncytial virus (RSV) may have a dysfunctional innate immune response that relates to the severity of their disease.

10 Dec 2012

BioCision introduces cryopreservation products to support stem cell research programs

As part of its ongoing effort to support the scientific community, BioCision LLC, a leader in the advanced temperature management of biomedical samples, announced the availability of free "Cool Stem Kits" to academic stem cell research programs in the U.S. and Europe.

10 Dec 2012

Vorinostat reduces risk of graft-vs.-host disease from bone marrow transplant treatments

A new class of drugs reduced the risk of patients contracting a serious and often deadly side effect of lifesaving bone marrow transplant treatments, according to a study from researchers at the University of Michigan Comprehensive Cancer Center.

10 Dec 2012

Ibrutinib may effectively combat chronic lymphocytic leukemia

The promising investigational targeted therapy ibrutinib and its mechanism of silencing gene communication pathways critical to the development of cancer may be an effective way to combat chronic lymphocytic leukemia (CLL), according to studies presented today at the 54th Annual Meeting of the American Society of Hematology (ASH).

10 Dec 2012

Wellcome Trust researchers discover how brain assesses confidence in its decisions

Wellcome Trust researchers have discovered how the brain assesses confidence in its decisions. The findings explain why some people have better insight into their choices than others.

10 Dec 2012

Angiocidin reduces acute myeloid leukemia cells in vivo by almost two-thirds in pre-clinical studies

Angiocidin, a novel tumor-inhibiting protein, has been shown to reduce acute myeloid leukemia (AML) cells in vivo by almost two-thirds in pre-clinical experiments.

10 Dec 2012

Perimenopausal lifestyle modifications could reduce risk of breast cancer in obese woman

Obese women might be able to eliminate their increased risk for postmenopausal breast cancer by taking measures during perimenopause to prevent weight gain and to therapeutically control the metabolic effects of their obesity, according to the results of a preclinical study published in Cancer Research, a journal of the American Association for Cancer Research.

10 Dec 2012

BlueGenics aims to discover new drugs from deep sea to combat osteoporosis

Searching for substances from the deep sea to combat osteoporosis and other human common diseases is one of the objectives of the new European research project "BlueGenics" which has received funding of EUR 6 million from the European Commission.

10 Dec 2012

New 3D culture system mimics environment surrounding inflammatory breast cancer cells

Inflammatory breast cancer (IBC) is a very rare and aggressive disease that progresses rapidly and is associated with a very low survival rate. To understand how this type of cancer spreads, it's crucial to characterize the interactions between cancer cells and their 3D environment.

10 Dec 2012

Scientists uncover molecular basis of gentle touch

Stroke the soft body of a newborn fruit fly larva ever-so-gently with a freshly plucked eyelash, and it will respond to the tickle by altering its movement-an observation that has helped scientists at the University of California, San Francisco (UCSF) uncover the molecular basis of gentle touch, one of the most fundamental but least well understood of our senses.

10 Dec 2012

Targeting RAD52 protein can block the process by which leukemia stem cells repair themselves

Despite treatment with imatinib, a successful drug that targets chronic myeloid leukemia (CML), a deadly type of cancer, some patients may continue to be at risk for relapse because a tiny pool of stem cells is resistant to treatment and may even accumulate additional genetic aberrations, eventually leading to disease progression and relapse. These leukemia stem cells are full of genetic errors, loaded with potentially lethal breaks in DNA, and are in a state of constant self-repair.

10 Dec 2012

FoxP3 gene expression identifies ALS disease progression in 80% of patients

The debilitating symptoms of amyotrophic lateral sclerosis, or ALS, appear to be increased by a lack of inflammation-reducing T cells, report scientists from the Methodist Neurological Institute in an upcoming print issue of The EMBO Molecular Medicine Journal.

10 Dec 2012

GSK, MD Anderson partner to develop new therapeutic antibodies against cancer

The University of Texas MD Anderson Cancer Center and GlaxoSmithKline (GSK) have signed a research collaboration and license agreement to develop new therapeutic antibodies that promote an immune system attack against cancer.

10 Dec 2012

Most triple-negative breast cancer patients have multiple genetic mutations after chemo treatment

Most triple-negative breast cancer patients who were treated with chemotherapy to shrink the tumor prior to surgery still had multiple genetic mutations in their tumor cells, according to a study by Vanderbilt-Ingram Cancer Center (VICC) investigators.

10 Dec 2012

C5aRA treatment could be effective against periodontitis

Periodontitis, a form of chronic gum disease that affects nearly half of the U.S. adult population, results when the bacterial community in the mouth becomes unbalanced, leading to inflammation and eventually bone loss. In its most severe form, which affects 8.5 percent of U.S. adults, periodontitis can impact systemic health.

9 Dec 2012

Novel sensor measures individual particles in blood samples

Norwegian researchers have developed the world's first sensor capable of measuring individual particles in a blood sample. This new innovation could cause a sensation in the medical world.

7 Dec 2012

Blocking specific protein increases vulnerability of tumors to treatment

Blocking a specific protein renders tumors more vulnerable to treatment in mice, suggesting new therapies could eventually achieve the same in humans, according to new research from Fox Chase Cancer Center to be presented at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium on Friday, December 7, 2012.

7 Dec 2012

Genomic tests increase accuracy of breast cancer diagnosis

The latest generation of genomic tests for breast cancer can improve physicians' ability to diagnose the disease and more precisely tailor each patient's treatment, according to a study being presented at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium (SABCS). The study examined the first commercially available genomic tests to determine the molecular subtype of a breast cancer tumor.

7 Dec 2012

Scientists identify underlying genetic cause for rare motor neurone disorder

Scientists have identified an underlying genetic cause for a rare disorder of motor neurones, and believe this may help find causes of other related diseases.

7 Dec 2012

Novel organic metamaterial holds promise for drug delivery

A bit reminiscent of the Terminator T-1000, a new material created by Cornell researchers is so soft that it can flow like a liquid and then, strangely, return to its original shape.

7 Dec 2012

Medical Science News

Severe RSV disease may impair innate immune response in infants

BioCision introduces cryopreservation products to support stem cell research programs

Vorinostat reduces risk of graft-vs.-host disease from bone marrow transplant treatments

Ibrutinib may effectively combat chronic lymphocytic leukemia

Wellcome Trust researchers discover how brain assesses confidence in its decisions

Angiocidin reduces acute myeloid leukemia cells in vivo by almost two-thirds in pre-clinical studies

Perimenopausal lifestyle modifications could reduce risk of breast cancer in obese woman

BlueGenics aims to discover new drugs from deep sea to combat osteoporosis

New 3D culture system mimics environment surrounding inflammatory breast cancer cells

Scientists uncover molecular basis of gentle touch

Targeting RAD52 protein can block the process by which leukemia stem cells repair themselves

FoxP3 gene expression identifies ALS disease progression in 80% of patients

GSK, MD Anderson partner to develop new therapeutic antibodies against cancer

Most triple-negative breast cancer patients have multiple genetic mutations after chemo treatment

C5aRA treatment could be effective against periodontitis

Novel sensor measures individual particles in blood samples

Blocking specific protein increases vulnerability of tumors to treatment

Genomic tests increase accuracy of breast cancer diagnosis

Scientists identify underlying genetic cause for rare motor neurone disorder

Novel organic metamaterial holds promise for drug delivery

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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