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Vanderbilt University scientists discover new approach to treating mood, anxiety disorders

Chemically modified inhibitors of the COX-2 enzyme relieve anxiety behaviors in mice by activating natural "endocannabinoids" without gastrointestinal side effects, Vanderbilt University scientists will report next week.

5 Aug 2013

Researchers find vital enzyme complex that gets elevated in many cancers

A team of researchers from Philadelphia and Norway has determined the structure of an enzyme complex that modifies one end of most human proteins and is made at elevated levels in numerous forms of cancer. A study in Nature Structural & Molecular Biology, led by researchers at The Wistar Institute, depicts the structure and the means of action of a protein complex called NatA.

5 Aug 2013

Necrostatin-1: A substance which counteracts several of aluminum's neurotoxic effects

New Studies in Mice Support Toxic Role of Aluminum in Neurodegenerative Conditions, According to Report in Restorative Neurology and Neuroscience

3 Aug 2013

New study paves way for novel approaches to protect people from infections

A new study published by University of Utah researchers is paving the way for novel approaches related to how people are immunized to protect them from diseases.

3 Aug 2013

Researchers exploit Japanese supercomputer to achieve largest general neuronal network simulation

By exploiting the full computational power of the Japanese supercomputer, K Computer, researchers from the RIKEN HPCI Program for Computational Life Sciences, the Okinawa Institute of Technology (OIST) in Japan and Forschungszentrum J-lich in Germany have carried out the largest general neuronal network simulation to date.

3 Aug 2013

HTR3 variants associated with effectiveness of ondansetron treatment for alcohol dependence

An experimental treatment for alcohol dependence works better in individuals who possess specific combinations of genes that regulate the function and binding of serotonin, a brain chemical affected by the treatment, according to a study supported by the National Institutes of Health. A report of the finding appears online in the American Journal of Psychiatry.

3 Aug 2013

Specific mutations in FLT3 receptor can contribute to acute myeloid leukemia

Specific mutations (N676K) in the FLT3 receptor can contribute to the development of acute myeloid leukemia. The FLT3 receptor regulates cell growth, while activating gene mutations promote the uncontrolled proliferation of white blood cells. These findings were reported in the specialist journal Blood by a group of scientists from the Helmholtz Zentrum München and the Hospital of the Ludwig Maximilians University in Munich as part of a clinical research collaboration with the German Cancer Consortium.

3 Aug 2013

New research may influence development of anti-viral therapies to fight against Dengue

New research into the fight against Dengue, an insect-borne tropical disease that infects up to 390 million people worldwide annually, may influence the development of anti-viral therapies that are effective against all four types of the virus.

3 Aug 2013

New findings may lead to first new animal model for hepatitis C virus

By differentiating monkey stem cells into liver cells and inducing successful infection, researchers from the Icahn School of Medicine at Mount Sinai have shown for the first time that the hepatitis C virus can replicate in monkeys, according to research published in the journal Gastroenterology.

3 Aug 2013

Video games boost player's visual skills but reduce ability to inhibit impulsive behavior

A person playing a first-person shooter video game like Halo or Unreal Tournament must make decisions quickly. That fast-paced decision-making, it turns out, boosts the player's visual skills but comes at a cost, according to new research: reducing the person's ability to inhibit impulsive behavior.

3 Aug 2013

Combating antibiotic resistance: an interview with Ron Najafi, CEO NovaBay Pharmaceuticals

Approximately 80 years ago the first antibiotic was discovered by Sir Alexander Fleming, for which he was justifiably awarded the Nobel Prize in medicine.

2 Aug 2013

Castle Biosciences to present DecisionDx-Melanoma test data at Summer Academy Meeting of AAD

Castle Biosciences Inc. announced that data from studies of its DecisionDx-Melanoma test are being presented today at the Summer Academy Meeting of the American Academy of Dermatology. The validation data confirm previous studies showing that the gene expression profile test is a strong independent predictor for classifying which Stage I or II non-metastatic cutaneous melanoma patients will likely recur.

2 Aug 2013

Keeping Alzheimer's disease in check

The future is looking good for drugs designed to combat Alzheimer's disease. EPFL scientists have unveiled how two classes of drug compounds currently in clinical trials work to fight the disease. Their research suggests that these compounds target the disease-causing peptides with high precision and with minimal side-effects.

2 Aug 2013

Thermo Fisher Scientific opens cell culture DPM production site in Singapore

Thermo Fisher Scientific Inc., the world leader in serving science, today announced it is expanding its global cell culture and bioprocessing capabilities by opening a new manufacturing plant in Singapore to produce dry powder media, a crucial cell culture raw material used to manufacture biologics, including vaccines, anti-cancer therapeutics, and others.

2 Aug 2013

ASH to award 2013 William Dameshek Prize to Andrew S. Weyrich

The American Society of Hematology will present the 2013 William Dameshek Prize to Andrew S. Weyrich, PhD, of The University of Utah for his seminal research on the cellular and molecular causes of blood clots.

2 Aug 2013

Build-up of harmful chemicals in the body affects people of all social standings

A new study published this week has found that the build-up of harmful chemicals in the body is affecting people of all social standings -- not just those from economically deprived backgrounds as previously thought.

2 Aug 2013

Protein linked to learning induces cocaine addiction, say researchers

A team of researchers says it has solved the longstanding puzzle of why a key protein linked to learning is also needed to become addicted to cocaine. Results of the study, published in the Aug. 1 issue of the journal Cell, describe how the learning-related protein works with other proteins to forge new pathways in the brain in response to a drug-induced rush of the “pleasure” molecule dopamine.

2 Aug 2013

Wild type genetic background affects outcomes of interactions between genetic mutations

In the current issue of PLOS Genetics, Michigan State University genetic scientists have begun to understand how the rest of the genome interacts with such mutations to cause the differences we see among individuals.

2 Aug 2013

Researchers now have more complete picture of mTORC1 pathway that can lead to cancer, diabetes

Deciphering the body's complex molecular pathways that lead to disease when they malfunction is highly challenging. Researchers at Sanford-Burnham Medical Research Institute now have a more complete picture of one particular pathway that can lead to cancer and diabetes. In the study published by Molecular Cell, the scientists uncovered how a protein called p62 has a cascade affect in regulating cell growth in response to the presence of nutrients such as amino acids and glucose. Disrupting this chain may offer a new approach to treating disease.

2 Aug 2013

Clinicians should be aware of use of herbal supplements while breastfeeding

In an article published in this month's issue of Pediatrics In Review, researchers from Boston University School of Medicine (BUSM) stress the importance of physicians recognizing that many mothers use herbal supplements while breastfeeding in order to make accurate health assessments for both mother and child.

2 Aug 2013

Medical Science News

Vanderbilt University scientists discover new approach to treating mood, anxiety disorders

Researchers find vital enzyme complex that gets elevated in many cancers

Necrostatin-1: A substance which counteracts several of aluminum's neurotoxic effects

New study paves way for novel approaches to protect people from infections

Researchers exploit Japanese supercomputer to achieve largest general neuronal network simulation

HTR3 variants associated with effectiveness of ondansetron treatment for alcohol dependence

Specific mutations in FLT3 receptor can contribute to acute myeloid leukemia

New research may influence development of anti-viral therapies to fight against Dengue

New findings may lead to first new animal model for hepatitis C virus

Video games boost player's visual skills but reduce ability to inhibit impulsive behavior

Combating antibiotic resistance: an interview with Ron Najafi, CEO NovaBay Pharmaceuticals

Castle Biosciences to present DecisionDx-Melanoma test data at Summer Academy Meeting of AAD

Keeping Alzheimer's disease in check

Thermo Fisher Scientific opens cell culture DPM production site in Singapore

ASH to award 2013 William Dameshek Prize to Andrew S. Weyrich

Build-up of harmful chemicals in the body affects people of all social standings

Protein linked to learning induces cocaine addiction, say researchers

Wild type genetic background affects outcomes of interactions between genetic mutations

Researchers now have more complete picture of mTORC1 pathway that can lead to cancer, diabetes

Clinicians should be aware of use of herbal supplements while breastfeeding

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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