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Roche's gantenerumab removes amyloid plaques from the brain of patients with AD

Roche today announced the publication of a study demonstrating that its monoclonal antibody gantenerumab removes amyloid plaques from the brain of patients with Alzheimer's disease. The study "Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab" is published today in the October issue of Archives in Neurology.

11 Oct 2011

Gantenerumab appears to reduce brain amyloid levels in patients with AD

Although it is a small study and more clinical trials are needed, treatment with the medication gantenerumab appeared to result in a reduction in brain amyloid levels in patients with Alzheimer disease, according to a report published Online First by Archives of Neurology, one of the JAMA/Archives journals.

11 Oct 2011

Normal Htt protein regulates formation of cellular structures in mouse model of HD

Huntington disease is a devastating neurogenerative disorder that causes a progressive loss of functional capacity and reduced life span. It is an inherited condition caused by a mutant HTT gene. Although this has been known for many years, the functions of the normal Htt protein and the mechanisms by which the mutant protein generated from the mutant HTT gene causes disease are not well understood.

11 Oct 2011

Sirt1 protein enhances skeletal muscle insulin sensitivity in calorie-restricted mice

The number of individuals with type 2 diabetes is reaching epidemic proportions. One of the main risk factors for developing type 2 diabetes is resistance of cells in the body (particularly liver, fat, and skeletal muscle cells) to the effects of the hormone insulin.

11 Oct 2011

Genetics & IVF Institute now offers 24 Chromosome Microarray

The Genetics & IVF Institute is now offering 24 Chromosome Microarray, which is a new, comprehensive test used as part of an IVF cycle to evaluate the number of chromosomes present in an embryo before it is transferred to the mother.

11 Oct 2011

CXCL12 protein can inhibit metastasis of colon and melanoma cancers

Researchers at the Medical College of Wisconsin have shown that a protein can inhibit metastasis of colon and melanoma cancers. The findings are published in the October 10, 2011 issue of Proceedings of the National Academy of Sciences.

11 Oct 2011

New information about effects of aging on the brain

Research by biologists at the University of York and Hull York Medical School has revealed important new information about the way the brain is affected by age.

11 Oct 2011

Four-gene signature may predict patients at higher risk of OSCC recurrence

Oral Squamous Cell Carcinoma (OSCC) is responsible for nearly a quarter of all head and neck cancers. It is one of the leading causes of cancer death - largely due to the failure of current histological procedures in predicting the recurrence of the disease. New research published in BioMed Central's open access journal BMC Cancer shows that a four-gene signature may accurately predict which patients are at higher risk of OSCC recurrence.

11 Oct 2011

FDA clears Cardium's new Excellagen topical gel for diabetic foot ulcers

Cardium Therapeutics announced today that it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market and sell the Company's new Excellagen professional-use, sterile, syringe-based advanced wound care product for the management of diabetic foot ulcers and other dermal wounds.

11 Oct 2011

Case Western Reserve wins NCI grant to study genetic determinants of esophageal cancer

Case Western Reserve University School of Medicine and the Case Comprehensive Cancer Center are proud to announce the receipt of a highly competitive $5.4 million grant to study genetic determinants of Barrett's esophagus and esophageal adenocarcinoma.

11 Oct 2011

Awards showcase Australia’s promising future in bio-sciences

The six state winners of the AusBiotech/GSK Student Excellence Awards, announced today, will next week compete for the national biosciences research award at AusBiotech 2011.

10 Oct 2011

Potential vaccine against trachoma

An attenuated, or weakened, strain of Chlamydia trachomatis bacteria can be used as a vaccine to prevent or reduce the severity of trachoma, the world's leading cause of infectious blindness, suggest findings from a National Institutes of Health study in monkeys.

10 Oct 2011

Cannabis use leads to increased risk of depression in young people with specific genotype

Young people who are genetically vulnerable to depression should be extra careful about using cannabis: smoking cannabis leads to an increased risk of developing depressive symptoms.

10 Oct 2011

Study identifies new classes of breast stem cells responsible for mammary gland development

Publication in Nature advanced on line publication : researchers at the Université libre de Bruxelles, ULB identify distinct types of stem cells that contribute to mammary gland development and maintenance.

10 Oct 2011

Scientists identify 16M SNPs that associate with risk of gout, serum uric acid levels

Scientists at deCODE Genetics and academic collaborators from Iceland, Norway, Denmark, the Netherlands and the USA report the discovery of low frequency variants in the human genome that associate with risk of gout, a common inflammatory arthritis, and serum uric acid levels.

10 Oct 2011

Scientists identify first DNA faults linked to melanoma

Cancer Research UK scientists have discovered the first DNA faults linked to melanoma - the deadliest skin cancer - that are not related to hair, skin or eye colour, according to research published in Nature Genetics today.

10 Oct 2011

New siRNA treatment reduces damaging inflammation in animals models of several disorders

Massachusetts General Hospital (MGH) researchers - along with collaborators from Massachusetts Institute of Technology (MIT) and Alnylam Pharmaceuticals - have found a way to block, in an animal model, the damaging inflammation that contributes to many disease conditions.

10 Oct 2011

First successful quantification of membrane lipids in a living cell

Could controlling cell-membrane fat play a key role in turning off disease? Researchers at the University of Illinois at Chicago think so, and a biosensor they've created that measures membrane lipid levels may open up new pathways to disease treatment.

10 Oct 2011

Lack of sleep during adolescence could lead to more than dragging, foggy teens

An ongoing lack of sleep during adolescence could lead to more than dragging, foggy teens, a University of Wisconsin-Madison study suggests.

10 Oct 2011

Researchers focus on gelatinase inhibitor compounds to treat neurological diseases

Results of a study by a group of University of Notre Dame researchers represent a promising step on the road to developing new drugs for a variety of neurological diseases.

10 Oct 2011

Medical Science News

Roche's gantenerumab removes amyloid plaques from the brain of patients with AD

Gantenerumab appears to reduce brain amyloid levels in patients with AD

Normal Htt protein regulates formation of cellular structures in mouse model of HD

Sirt1 protein enhances skeletal muscle insulin sensitivity in calorie-restricted mice

Genetics & IVF Institute now offers 24 Chromosome Microarray

CXCL12 protein can inhibit metastasis of colon and melanoma cancers

New information about effects of aging on the brain

Four-gene signature may predict patients at higher risk of OSCC recurrence

FDA clears Cardium's new Excellagen topical gel for diabetic foot ulcers

Case Western Reserve wins NCI grant to study genetic determinants of esophageal cancer

Awards showcase Australia’s promising future in bio-sciences

Potential vaccine against trachoma

Cannabis use leads to increased risk of depression in young people with specific genotype

Study identifies new classes of breast stem cells responsible for mammary gland development

Scientists identify 16M SNPs that associate with risk of gout, serum uric acid levels

Scientists identify first DNA faults linked to melanoma

New siRNA treatment reduces damaging inflammation in animals models of several disorders

First successful quantification of membrane lipids in a living cell

Lack of sleep during adolescence could lead to more than dragging, foggy teens

Researchers focus on gelatinase inhibitor compounds to treat neurological diseases

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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