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NCI investigators design genetically engineered mouse to study human lung squamous cell carcinoma

National Cancer Institute (NCI) investigators have designed a genetically engineered mouse for use in the study of human lung squamous cell carcinoma (SCC). SCC is a type of non-small cell lung carcinoma, one of the most common types of lung cancer, with a five-year survival rate of about 15 percent.

18 Apr 2013

New combination therapies with anti-sickling capabilities needed for sickle cell disease

Pain is an undeniable focal point for patients with sickle cell disease but it's not the best focus for drug development, says one of the dying breed of physicians specializing in the condition.

18 Apr 2013

University of Florence professor awarded ESCEO-IOF Servier Pierre D. Delmas Prize

Today, at the opening of the European Congress on Osteoporosis & Osteoarthritis in Rome, Italy, Professor Maria Luisa Brandi MD, Professor of Endocrinology and Metabolic Diseases at the University of Florence, Florence, Italy was presented with ESCEO-IOF Servier Pierre D. Delmas Prize.

18 Apr 2013

Study highlights importance of zebrafish as a model organism for human disease research

Researchers demonstrate today that 70 per cent of protein-coding human genes are related to genes found in the zebrafish and that 84 per cent of genes known to be associated with human disease have a zebrafish counterpart.

18 Apr 2013

ESCEO and IOF honor Dr. Mary L. Bouxsein with ESCEO-IOF Herbert Fleisch Medal

Dr. Mary L. Bouxsein has been awarded the ESCEO-IOF Herbert Fleisch Medal in honor of her work in the field of skeletal fragility.

18 Apr 2013

CRISPR helps some bacteria evade mammalian immune system

CRISPR, a system of genes that bacteria use to defend themselves against viruses, has been found to be involved in helping some bacteria evade the mammalian immune system.

18 Apr 2013

Animal medication studies may lead way in discovering new drugs to relieve human suffering

It's been known for decades that animals such as chimpanzees seek out medicinal herbs to treat their diseases. But in recent years, the list of animal pharmacists has grown much longer, and it now appears that the practice of animal self-medication is a lot more widespread than previously thought, according to a University of Michigan ecologist and his colleagues.

18 Apr 2013

NCI researchers overcome major impediment to development of effective stem cell therapies

Scientists have overcome a major impediment to the development of effective stem cell therapies by studying mice that lack CD47, a protein found on the surface of both healthy and cancer cells.

18 Apr 2013

Scientists reveal that stem cells, tissue-specific cells can be grown from mature mammalian cells

tem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the National Institutes of Health.

18 Apr 2013

UTHealth neuroscientists demonstrate new strategy to overcome memory deficits

Neuroscientists at The University of Texas Health Science Center at Houston have taken a major step in their efforts to help people with memory loss tied to brain disorders such as Alzheimer's disease.

18 Apr 2013

Findings hold promise for development of therapies to fight different viral infections

The human body has the ability to ward off viruses by activating a naturally occurring protein at the cellular level, setting off a chain reaction that disrupts the levels of cholesterol required in cell membranes to enable viruses to enter cells.

18 Apr 2013

UTMB researchers identify protein that can interfere with the brain's response to leptin

Ever since the appetite-regulation hormone called leptin was discovered in 1994, scientists have sought to understand the mechanisms that control its action. It was known that leptin was made by fat cells, reduced appetite and interacted with insulin , but the precise molecular details of its function -details that might enable the creation of a new treatment for obesity - remained elusive.

18 Apr 2013

New research sheds light on successful ovulation and fertilization

Eggs take a long time to produce in the ovary, and thus are one of a body's precious resources. It has been theorized that the body has mechanisms to help the ovary ensure that ovulated eggs enter the reproductive tract at the right time in order to maximize the chance of successful fertilization.

18 Apr 2013

New pre-clinical study suggests novel drug combination therapy for leukemia treatment

A new, pre-clinical study by researchers at Virginia Commonwealth University Massey Cancer Center suggests that a novel drug combination could lead to profound leukemia cell death by disrupting the function of two major pro-survival proteins.

18 Apr 2013

Researchers find potential new genetic chemotherapy approach for cancer treatment

Researchers at The Jackson Laboratory have identified a molecule that prevents repair of some cancer cells, providing a potential new "genetic chemotherapy" approach to cancer treatment that could significantly reduce side effects and the development of treatment resistance compared with traditional chemotherapy.

18 Apr 2013

Examining function of all genes in zebrafish genome could benefit human health, researchers say

Equipped with the zebrafish genome, researchers have designed a method to assay the function of each and every gene and to explore the effects genetic variation has on zebrafish.

18 Apr 2013

Research findings could lead to novel approaches for eliminating reservoirs of HIV-1

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the protein that blocks HIV-1 from multiplying in white blood cells is regulated.

18 Apr 2013

Investigators report that cell-permeable NLS peptide shows promise in controlling atherosclerotic disease

Atherosclerosis - sometimes called "hardening of the arteries" - is a leading cause of death and morbidity in Western countries. A cell-permeable peptide containing the NF-ĸB nuclear localization sequence (NLS) shows promise as a potential agent in controlling the development of atherosclerotic disease.

18 Apr 2013

New research reveals how acute stress primes brain for improved performance

Overworked and stressed out? Look on the bright side. Some stress is good for you. "You always think about stress as a really bad thing, but it's not," said Daniela Kaufer, associate professor of integrative biology at the University of California, Berkeley.

17 Apr 2013

Research: Transcription factors regulating oxygen levels in blood play a role in melanoma metastases

Researchers at the University of North Carolina have discovered that transcription factors regulating the levels of oxygen in the blood also play a role in the spread of the skin cancer melanoma.

17 Apr 2013

Medical Science News

NCI investigators design genetically engineered mouse to study human lung squamous cell carcinoma

New combination therapies with anti-sickling capabilities needed for sickle cell disease

University of Florence professor awarded ESCEO-IOF Servier Pierre D. Delmas Prize

Study highlights importance of zebrafish as a model organism for human disease research

ESCEO and IOF honor Dr. Mary L. Bouxsein with ESCEO-IOF Herbert Fleisch Medal

CRISPR helps some bacteria evade mammalian immune system

Animal medication studies may lead way in discovering new drugs to relieve human suffering

NCI researchers overcome major impediment to development of effective stem cell therapies

Scientists reveal that stem cells, tissue-specific cells can be grown from mature mammalian cells

UTHealth neuroscientists demonstrate new strategy to overcome memory deficits

Findings hold promise for development of therapies to fight different viral infections

UTMB researchers identify protein that can interfere with the brain's response to leptin

New research sheds light on successful ovulation and fertilization

New pre-clinical study suggests novel drug combination therapy for leukemia treatment

Researchers find potential new genetic chemotherapy approach for cancer treatment

Examining function of all genes in zebrafish genome could benefit human health, researchers say

Research findings could lead to novel approaches for eliminating reservoirs of HIV-1

Investigators report that cell-permeable NLS peptide shows promise in controlling atherosclerotic disease

New research reveals how acute stress primes brain for improved performance

Research: Transcription factors regulating oxygen levels in blood play a role in melanoma metastases

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

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