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TSRI scientists identify key triggers of cancer-blocking mechanism in cells

Scientists at The Scripps Research Institute have identified key triggers of an important cancer-blocking mechanism in cells.

12 Jun 2013

Mayo Clinic announces first US stem cell clinical trial for children with hypoplastic left heart syndrome

Mayo Clinic has announced the first U.S. stem cell clinical trial for pediatric congenital heart disease. The trial aims to determine how stem cells from autologous umbilical cord blood can help children with hypoplastic left heart syndrome, a rare defect in which the left side of the heart is critically underdeveloped.

12 Jun 2013

Johns Hopkins researchers develop experimental vaccine for TB meningitis

A team of Johns Hopkins researchers working with animals has developed a vaccine that prevents the virulent TB bacterium from invading the brain and causing the highly lethal condition TB meningitis, a disease that disproportionately occurs in TB-infected children and in adults with compromised immune system.

12 Jun 2013

PSMA enzyme could become hallmark of new generation of biomarkers for prostate cancer treatment

No matter where they have hidden, metastatic prostate cancer cells still express some of the same signaling as normal prostate cells; in some cases even more so, as with the PSMA enzyme. Harnessing this enzyme could mean the beginning of a new platform for prostate cancer detection, staging, treatment and post-treatment monitoring, say researchers at the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting.

12 Jun 2013

Understanding Phelan-McDermid Syndrome

In the first prospective study of its kind, Seaver Autism Center researchers at the Icahn School of Medicine at Mount Sinai provide new evidence of the severity of intellectual, motor, and speech impairments in a subtype of autism called Phelan-McDermid Syndrome.

12 Jun 2013

Research could lead to new ways to combat chlamydia

A protein secreted by the chlamydia bug has a very unusual structure, according to scientists in the School of Medicine at The University of Texas Health Science Center San Antonio. The discovery of the protein's shape could lead to novel strategies for diagnosing and treating chlamydia, a sexually transmitted disease that infects an estimated 2.8 million people in the U.S. each year.

12 Jun 2013

Research discovery could shed light on unsolved cases of arrhythmia

The heart's regular rhythm is crucial to the delivery of oxygenated blood and nutrients to all the organs of the body. It is regulated by a bundle of cells called "the pacemaker," which use electrical signals to set the pace of the heart. Dysfunction in this mechanism can lead to an irregular heartbeat, known as arrhythmia, and often necessitates the implantation of an artificial pacemaker.

12 Jun 2013

Studies demonstrate that combined therapy could destroy drug-resistant cells within melanoma tumor

Advanced metastatic melanoma is a disease that has proven difficult to eradicate. Despite the success of melanoma-targeting drugs, tumors inevitably become drug resistant and return, more aggressive than before. In the current issue of the journal Cancer Cell, however, researchers at The Wistar Institute describe how they increase the effectiveness of anti-melanoma drugs by combining anticancer therapies with diabetes drugs.

12 Jun 2013

Research finding offers new insight into stroke rehabilitation

A new study finds that stroke patients' brains show strong cortical motor activity when observing others performing physical tasks - a finding that offers new insight into stroke rehabilitation.

12 Jun 2013

Nimodipine reduces febrile seizures

Fever-induced childhood seizures, known as febrile seizures, can be terrifying for parents to witness. The full-body convulsions, which mostly affect children six months to five years old, can last from mere seconds up to more than 40 minutes. Currently, children are not treated with daily anticonvulsant medication to prevent these seizures even when they recur repeatedly because toxic side effects of existing treatments outweigh potential benefits.

12 Jun 2013

Surgical oncologist receives grant further explore tumor suppressor function of mutated gene

Darren Carpizo, MD, PhD, a surgical oncologist in the Liver Cancer and Bile Duct Cancer Care Program at the Cancer Institute of New Jersey, has been awarded a $200,000 grant from the Sidney Kimmel Foundation for Cancer Research to further explore the effects of a compound identified in his laboratory found to restore tumor suppressor function of a mutated gene in cancer cells.

11 Jun 2013

Study shows iron-uptake receptor plays a role in HCV infection

Hepatitis C virus (HCV) infects more than 170 million people worldwide. Approximately 80 percent of infections lead to chronic illness including fibrosis, cirrhosis, cancer and also hepatic iron overload.

11 Jun 2013

Brandeis University professor receives 2013 Neuroscience Prize for pioneering contributions in neural circuits

Eve Marder, PhD, a professor of neuroscience at Brandeis University, is the recipient of the 2013 Neuroscience Prize of The Gruber Foundation. Marder is being honored with this prestigious international award for her pioneering contributions to the understanding of neural circuits, particularly how the properties and dynamics of neural circuits give rise to specific behaviors.

11 Jun 2013

Methylation changes related to immune function can moderate symptoms in schizophrenia patients

A study in Schizophrenia Bulletin is among the first to indicate epigenetic changes related to immune function in schizophrenia. DNA methylation, a process involving the addition of a methyl group to the DNA without changing its sequence, can alter gene expression.

11 Jun 2013

Combination of cell-killing radioactive particle and antibody is safe for treating cancers

An experimental treatment that combines a cell-killing radioactive particle with an antibody that homes in on cancer cells is safe in the treatment of cancers spreading through patients' abdomens, according to data from a first-in-human study presented today at the Society of Nuclear Medicine and Molecular Imaging annual meeting in Vancouver.

11 Jun 2013

Rapamycin improves cardiac function in mice suffering from age-related heart disease

Elderly mice suffering from age-related heart disease saw a significant improvement in cardiac function after being treated with the FDA-approved drug rapamycin for just three months.

11 Jun 2013

University of Nottingham scientists discover previously undetected layer in the cornea

Scientists at The University of Nottingham have discovered a previously undetected layer in the cornea, the clear window at the front of the human eye.

11 Jun 2013

Brain circuits involved in compulsive behavior reveal a surprising connection with obesity

What started as an experiment to probe brain circuits involved in compulsive behavior has revealed a surprising connection with obesity.

11 Jun 2013

Virginia Tech's Chang Lu awarded new NIH grant to research on cancer

Progress made in the technology development for studying protein-DNA interactions, conducted by Chang Lu, associate professor of chemical engineering and a core faculty member of the School of Biomedical Engineering and Sciences at Virginia Tech, has led to the National Institutes of Health (NIH) awarding a new project to continue his groundbreaking work.

11 Jun 2013

OncoSec Medical signs Sponsored Research Agreement with ODU for melanoma study

OncoSec Medical Inc., a company developing its advanced-stage ImmunoPulse DNA-based immunotherapy and NeoPulse therapy to treat solid tumors, signed a Sponsored Research Agreement with Old Dominion University and the Frank Reidy Research Center for Bioelectrics.

11 Jun 2013

Medical Science News

TSRI scientists identify key triggers of cancer-blocking mechanism in cells

Mayo Clinic announces first US stem cell clinical trial for children with hypoplastic left heart syndrome

Johns Hopkins researchers develop experimental vaccine for TB meningitis

PSMA enzyme could become hallmark of new generation of biomarkers for prostate cancer treatment

Understanding Phelan-McDermid Syndrome

Research could lead to new ways to combat chlamydia

Research discovery could shed light on unsolved cases of arrhythmia

Studies demonstrate that combined therapy could destroy drug-resistant cells within melanoma tumor

Research finding offers new insight into stroke rehabilitation

Nimodipine reduces febrile seizures

Surgical oncologist receives grant further explore tumor suppressor function of mutated gene

Study shows iron-uptake receptor plays a role in HCV infection

Brandeis University professor receives 2013 Neuroscience Prize for pioneering contributions in neural circuits

Methylation changes related to immune function can moderate symptoms in schizophrenia patients

Combination of cell-killing radioactive particle and antibody is safe for treating cancers

Rapamycin improves cardiac function in mice suffering from age-related heart disease

University of Nottingham scientists discover previously undetected layer in the cornea

Brain circuits involved in compulsive behavior reveal a surprising connection with obesity

Virginia Tech's Chang Lu awarded new NIH grant to research on cancer

OncoSec Medical signs Sponsored Research Agreement with ODU for melanoma study

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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