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Anti-TNF therapies may reduce Alzheimer's risk among people with rheumatoid arthritis

Anti-TNF therapies commonly used to treat rheumatoid arthritis have been found to potentially reduce the risk of developing Alzheimer's dementia among people with rheumatoid arthritis, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Atlanta.

8 Nov 2010

Blocking beta glucuronidase enzyme could eliminate side effects of CPT-11 in colon cancer treatment

A debilitating side effect of a widely used but harshly potent treatment for colon cancer could be eliminated if a promising new laboratory discovery bears fruit.

8 Nov 2010

Research on immune system may help develop improved vaccines for cancer

Researchers at the University of Cambridge hope to revolutionise cancer therapy after discovering one of the reasons why many previous attempts to harness the immune system to treat cancerous tumours have failed.

8 Nov 2010

Research findings on RGL2 protein can lead to new therapeutic target for pancreatic cancer

One of the most frustrating problems faced by doctors who treat pancreatic cancer is the lack of effective therapeutic options. More than 38,000 people in the United States die of the disease each year, and new drugs and treatments are desperately needed.

8 Nov 2010

Brain training improves real-world activities of older adults

A new study published in the Journal of the American Geriatrics Society (JAGS) proves that the right kind of brain training can produce cognitive improvements that transfer to real-world skills. The study, available online and in the November 2010 issue of JAGS found that older drivers who completed 10 sessions of speed-of-processing training or reasoning training had an approximately 50 percent reduction in at-fault motor-vehicle collisions (MVC) compared to the control group.

8 Nov 2010

UC researchers receive four-year grant to study mechanism of malarial parasite replication in RBCs

Today, about half the world's population lives in areas at risk of malaria transmission. The disease is transmitted to humans through bites from mosquitoes, and each year causes hundreds of thousands of deaths worldwide, with about 1,500 of these in the United States.

8 Nov 2010

New findings could help scientists devise optimal therapies for Friedreich's ataxia

Scripps Research Institute scientists have taken a step closer to understanding the cause of Friedreich's ataxia, a debilitating neurological condition that affects tens of thousands of people worldwide, and so far has no cure.

8 Nov 2010

TRPM7 protein plays a key role in maintenance of magnesium homeostasis

An international team led by researchers at the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School has published new findings that demonstrate how a specific protein controls the body's ability to balance magnesium levels. Magnesium is an essential element for good health and is critical to more than 300 biochemical reactions that occur in the body.

8 Nov 2010

Scientists identify genes that enable some immune systems to halt HIV; finding could spur drug, vaccine development

Tiny variants in a protein that alerts the body to infection could explain how one in 300 HIV-infected people are able to resist the onset of AIDS for years without needing any treatment, researchers said Thursday in a study published online in the journal Science, Agence France-Presse reports

8 Nov 2010

Researchers identify key step in metabolic pathways linked to diabetes and cancer

United States and Japanese researchers have identified a key step in metabolic pathways linked to diabetes and cancer. The study on activation of the protein complex TORC 2 was published online in the journal Current Biology Oct. 28.

8 Nov 2010

Chronic lower back pain may be linked to axial spondyloarthritis: Research

Chronic lower back pain may be linked to a recently defined form of inflammatory arthritis known as axial spondyloarthritis, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Atlanta.

8 Nov 2010

Prolonged separation from mother increases risk of breast cancer in young mice

Young mice that experienced the psychosocial stress of prolonged separation from their mothers had a higher incidence and faster onset of breast tumors compared with young mice who did not experience this stressful life event. Specifically, neonatal mice separated from their mothers for a prolonged period of time developed mammary tumors twice as fast as mice that experienced short or no maternal separation.

8 Nov 2010

Gout and hyperuricemia continue to rise in the U.S.

Gout rates and related cases of hyperuricema have increased over the past two decades, according to research presented at the Nov 2010, American College of Rheumatology Annual Scientific Meeting in Atlanta.

8 Nov 2010

Agios receives two grants under QTDP program to develop novel cancer metabolism therapies

Agios Pharmaceuticals, the leading biopharmaceutical company focused on discovering and developing novel drugs in the rapidly emerging field of cancer metabolism, today announced it has received two grants totaling more than $488,000 from the Qualifying Therapeutic Discovery Project (QTDP) Program.

8 Nov 2010

Researchers take first step towards understanding of rare skin cancer

Leeds-based scientists, funded by Yorkshire Cancer Research headquartered in Harrogate, North Yorkshire, plan to introduce the genetic material of a virus into normal human skin cells to produce skin cells that have features of Merkel Cell Carcinoma cancers.

8 Nov 2010

Eleven Biotherapeutics receives QTDP grants for lead protein-based discovery programs

Eleven Biotherapeutics, a biopharmaceutical company focused on translating breakthrough discoveries from science and medicine to engineer and develop innovative protein-based therapeutics, today announced the receipt of three grants totaling more than $733,000 from the Qualifying Therapeutic Discovery Project (QTDP) Program.

8 Nov 2010

Genentech announces Phase II RG7204 clinical study results for metastatic melanoma tumors

Genentech, Inc., a member of the Roche Group today announced results from a Phase II clinical study of RG7204 (PLX4032), an investigational first-in-class molecule designed to selectively inhibit a cancer-causing, mutated form of the BRAF protein found in approximately half of metastatic melanoma tumors.

8 Nov 2010

InNexus receives $116,760 cash grant under QTDP program to develop DXL anti-cancer antibodies

InNexus Biotechnology Inc. a leading drug development company commercializing the next generation of antibodies based on its groundbreaking Dynamic Cross Linking (DXL) technology, today announced it has been awarded a cash grant by the U.S. government totaling $116,760 for projects related to the Company's development of DXL anti-cancer antibodies.

8 Nov 2010

Deletion of 17q12 chromosomal region increases risk factor for ASD, schizophrenia

Researchers have identified the deletion of a genomic region on chromosome 17 as a significant risk factor for autism spectrum disorders (ASD) and schizophrenia. A mutation of one of the genes in the deleted interval already is a known cause of renal cysts and diabetes syndrome (RCAD).

8 Nov 2010

Researchers identify gene linked to melanoma metastasis

Researchers at Washington University School of Medicine in St. Louis have identified a gene linked to the spread of eye melanoma.

8 Nov 2010

Medical Science News

Anti-TNF therapies may reduce Alzheimer's risk among people with rheumatoid arthritis

Blocking beta glucuronidase enzyme could eliminate side effects of CPT-11 in colon cancer treatment

Research on immune system may help develop improved vaccines for cancer

Research findings on RGL2 protein can lead to new therapeutic target for pancreatic cancer

Brain training improves real-world activities of older adults

UC researchers receive four-year grant to study mechanism of malarial parasite replication in RBCs

New findings could help scientists devise optimal therapies for Friedreich's ataxia

TRPM7 protein plays a key role in maintenance of magnesium homeostasis

Scientists identify genes that enable some immune systems to halt HIV; finding could spur drug, vaccine development

Researchers identify key step in metabolic pathways linked to diabetes and cancer

Chronic lower back pain may be linked to axial spondyloarthritis: Research

Prolonged separation from mother increases risk of breast cancer in young mice

Gout and hyperuricemia continue to rise in the U.S.

Agios receives two grants under QTDP program to develop novel cancer metabolism therapies

Researchers take first step towards understanding of rare skin cancer

Eleven Biotherapeutics receives QTDP grants for lead protein-based discovery programs

Genentech announces Phase II RG7204 clinical study results for metastatic melanoma tumors

InNexus receives $116,760 cash grant under QTDP program to develop DXL anti-cancer antibodies

Deletion of 17q12 chromosomal region increases risk factor for ASD, schizophrenia

Researchers identify gene linked to melanoma metastasis

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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