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Cyclacel's CYC065 CDK inhibitor demonstrates potential against breast cancer resistant to trastuzumab

Cyclacel Pharmaceuticals, Inc., today announced the publication of preclinical data in the Proceedings of the National Academy of Sciences (PNAS), demonstrating that cyclin E plays a major role in making Human Epidermal growth factor Receptor 2 positive (HER2+) breast cancer resistant to trastuzumab (Herceptin®), a widely used medicine for breast cancer patients who test positive for HER2.

18 Feb 2011

TI Pharma launches new research project on stem cell transplant

Top Institute Pharma is today launching a new research project that should make stem cell transplants more successful. A stem cell transplant is usually performed on adults with acute leukemia.

18 Feb 2011

New approaches for controlling sleeping sickness caused by trypanosomes

The research could eventually lead to new approaches for controlling sleeping sickness in humans and wasting diseases in livestock which are caused by trypanosomes carried by the bloodsucking tsetse fly.

18 Feb 2011

Scientists discover axons can send signals to cell body

Neurons are complicated, but the basic functional concept is that synapses transmit electrical signals to the dendrites and cell body, and axons carry signals away.

18 Feb 2011

Researchers identify normal movement mechanisms of PrPC in brain

Researchers at the University of California, San Diego School of Medicine have identified the motors that move non-infectious prion proteins (PrPC) - found within many mammalian cells - up and down long, neuronal transport pathways.

18 Feb 2011

Smoking, exercise influence Vitamin E's effect on pneumonia risk

Depending on the level of smoking and leisure time exercise, vitamin E supplementation may decrease or increase, or may have no effect, on the risk of pneumonia, according to a study published in Clinical Epidemiology.

18 Feb 2011

Avenir team discovers how Neisseria meningitidis disseminates into bloodstream

Although, in the majority of cases, the localized presence of Neisseria meningitidis in the throat has no consequence, it can sometimes lead to meningitis or septicaemia. The seriousness of these two infections is driving researchers from around the world to improve their understanding of the mode of operation of this bacterium, which, once it leaves its favourite location becomes extremely dangerous.

18 Feb 2011

Sleeping Trojan horse technique resolves some difficulties in transporting metal ions into cells

A unique strategy developed by researchers at Cardiff University is opening up new possibilities for improving medical imaging.

18 Feb 2011

World's first cancer stem cell-targeting chemical missile

Deakin University medical scientists have created the world's first cancer stem cell-targeting chemical missile, placing them a step closer to creating a medical 'smart bomb' that would seek out and eradicate the root of cancer cells.

18 Feb 2011

Two studies investigate frontiers of islet cell transplantation for treating diabetes

Two studies published in the current issue of Cell Transplantation investigate frontiers of islet cell transplantation for treating diabetes. Researchers in Milan, Italy re-examine the role of bone marrow stem cells in diabetic therapy and islet cell regeneration and Canadian researchers offer improved strategies for optimizing pancreatic islet culture in vitro.

18 Feb 2011

Loyola offers stem cell transplants to older patients with leukemia and lymphoma

As the first baby boomers turn 65, Loyola University Hospital has begun offering stem cell transplants to leukemia and lymphoma patients who previously were too old to qualify.

18 Feb 2011

Statin drug may help prevent blindness in diabetics

New University of Georgia research has found that a statin drug that is often known by the brand-name Lipitor may help prevent blindness in people with diabetes.

17 Feb 2011

Skeleton regulates fertility in males, but not females

Researchers at Columbia University Medical Center have discovered that the skeleton acts as a regulator of fertility in male mice through a hormone released by bone, known as osteocalcin.

17 Feb 2011

Study: Preterm mothers’ milk contains low concentrations of coenzyme Q10

A study conducted at the University of Granada and at the University Hospital San Cecilio revealed that preterm mothers' milk contains low concentrations of coenzyme Q10. This is a complex of great medical importance, due both to its antioxidant capacity and to its role as a component of the electron transport chain, among other functions.

17 Feb 2011

New study: Fast food meal consumption can affect inflammatory responses in blood vessels

The effect of a high-fat meal on blood vessel walls can vary among individuals depending on factors such as their waist size and triglyceride levels, suggests new research at UC Davis.

17 Feb 2011

Iris Pharma announces validation of new EIU model of ocular inflammation

Iris Pharma, a world leader CRO specialized in ophthalmology, today announced the validation of the Endotoxin-Induced Uveitis model, a new model of ocular inflammation.

17 Feb 2011

Study: Cigarette smoking linked to mucus overproduction in patients with chronic bronchitis

Cigarette smoking has been linked with overproduction of mucus associated with chronic bronchitis, according to a study conducted by researchers in New Mexico. The study indicates cigarette smoke suppresses a protein that causes the natural death of mucus-producing cells in the airways of bronchitis patients.

17 Feb 2011

Medical Science News

Cyclacel's CYC065 CDK inhibitor demonstrates potential against breast cancer resistant to trastuzumab

TI Pharma launches new research project on stem cell transplant

New approaches for controlling sleeping sickness caused by trypanosomes

Scientists discover axons can send signals to cell body

Researchers identify normal movement mechanisms of PrPC in brain

Smoking, exercise influence Vitamin E's effect on pneumonia risk

Avenir team discovers how Neisseria meningitidis disseminates into bloodstream

Sleeping Trojan horse technique resolves some difficulties in transporting metal ions into cells

World's first cancer stem cell-targeting chemical missile

Two studies investigate frontiers of islet cell transplantation for treating diabetes

Loyola offers stem cell transplants to older patients with leukemia and lymphoma

Statin drug may help prevent blindness in diabetics

Skeleton regulates fertility in males, but not females

Study: Preterm mothers’ milk contains low concentrations of coenzyme Q10

New study: Fast food meal consumption can affect inflammatory responses in blood vessels

Iris Pharma announces validation of new EIU model of ocular inflammation

Study: Cigarette smoking linked to mucus overproduction in patients with chronic bronchitis

Positive preliminary data from ongoing PSMA ADC phase 1 study against prostate cancer

Two researchers receive Brupbacher Prize for Cancer Research 2011

CLC bio releases several desktop software packages for analyzing biological sequence data

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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