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Beta-catenin protein plays a key role in development of stem cells in acute leukaemia

Researchers at King's College London have discovered that leukaemic stem cells can be reversed to a pre-leukaemic stage by suppressing a protein called beta-catenin found in the blood.

14 Dec 2010

Diet linked to onset of mental illness

Changes in diet have been linked to a reduction of abnormal behaviors in mentally ill people or animals, but a Purdue University study shows that diet might also trigger the onset of mental illness in the first place.

14 Dec 2010

Reversible two-step binding mechanism to stop cancer cell growth

What makes cancer cells so dangerous is that they grow in an unregulated way and proliferate much faster than other cells. The proteasome, a large protein complex, plays a key role in this process: By breaking down used proteins for recycling, it clears the way for the next cycle.

14 Dec 2010

Study finds expression of toxic RNA that leads to Fragile X Tremor Ataxia Syndrome modifiable

Expression of a toxic RNA that leads to Fragile X Tremor Ataxia Syndrome is modifiable by genetic or pharmacologic means, according to new research from U-M Medical School scientists.

14 Dec 2010

Osteoporosis drug reduces bone loss in oral cancer

A drug currently approved for osteoporosis treatment has been shown to reduce bone loss in a study of mice with oral cancer, suggesting it could serve as an important supplemental therapy in patients with head and neck cancers that erode bone.

14 Dec 2010

Mouse study shows flu virus infection may protect against asthma

In a paper that suggests a new strategy to prevent asthma, scientists at Children's Hospital Boston and their colleagues report that the influenza virus infection in young mice protected the mice as adults against the development of allergic asthma.

14 Dec 2010

Drug to reverse immunological decline in aging

UCSF researchers have identified an existing medication that restores key elements of the immune system that, when out of balance, lead to a steady decline in immunity and health as people age.

14 Dec 2010

Novel labeling technique helps researchers to explore DNA chemical modification

Researchers at Emory University School of Medicine and the University of Chicago have developed a method for labeling and mapping a "sixth nucleotide," whose biological role scientists are only beginning to explore.

14 Dec 2010

BUSM professor wins 2010 Van Slyke Award for seminal contributions to laboratory medicine

Michael F. Holick, PhD, MD, a professor at Boston University School of Medicine (BUSM), is the recipient of the 2010 Van Slyke Award from the American Academy for Clinical Chemistry New York Metro Section.

14 Dec 2010

FOXA1 gene controls oestrogen-fuelled growth of breast cancer cells

CANCER RESEARCH UK scientists have discovered that a single gene controls the oestrogen-fuelled growth of breast cancer cells, according to research published in Nature Genetics on Sunday.

14 Dec 2010

New osteoporosis drug appears to reduce bone loss in mice with oral cancer

14 Dec 2010

University of Utrecht orders for Bruker 527 GHz Solid State DNP-NMR system

Bruker announces the first order for a novel and unique 527 GHz Solid State DNP-NMR system, based on an ultra-high field NMR system. Dynamic Nuclear Polarization (DNP) has been shown to greatly increase solid-state NMR sensitivity for numerous bio-solids and advanced materials research applications.

13 Dec 2010

Cedarlane to distribute TGR's new ELISA-One technology assay reagents in Canada and the US

TGR BioSciences, a leading global provider of advanced cell based assay technologies in the fields of cancer, kinase and GPCR research, is extremely pleased to announce a distribution partnership with Cedarlane Laboratories of Burlington, ON, Canada, a leading supplier of Life Science research reagents in North America.

13 Dec 2010

Inimex, SARomics Biostructures achieve scientific milestone in IMX942 IDR collaboration

Inimex Pharmaceuticals and SARomics Biostructures announce that they have achieved a scientific milestone in their collaboration to solve the structure of Inimex's Innate Defense Regulator (IDR) IMX942 in complex with its target, the ZZ domain of human p62 (sequestosome-1). No structures were previously available for this challenging protein domain. The crystal structure determined by SARomics Biostructures provides invaluable information that will assist the functional understanding of IMX942 and the development of the new generation of IDRs.

13 Dec 2010

Yissum introduces novel DNA profiling method for investigating complex crime scenes

Forensic DNA science has advanced significantly in the latest decade, and constitutes today the mainstay of forensic science. All serious crime scenes are routinely inspected for DNA evidence and many cases are solved by matching the DNA in the crime scene to that of a suspect. But often a crime scene will contain complex DNA mixtures (usually more than two individuals), and the detection of a particular DNA profile in such mixtures is challenging.

13 Dec 2010

Vical's Vaxfectin adjuvant boosts immune response of DNA-based vaccines against cancer

Vical Incorporated announced today that the company's Vaxfectin® adjuvant has significantly boosted the immune response of DNA-based vaccines against a range of pathogens and cancer in preclinical models from rodents to non-human primates. Vaxfectin® has demonstrated similar effects with protein- and peptide-based vaccines in preclinical models.

13 Dec 2010

Scientists create functioning human intestinal tissue from pluripotent stem cells

For the first time, scientists have created functioning human intestinal tissue in the laboratory from pluripotent stem cells.

13 Dec 2010

Origin of Haiti cholera epidemic traced to South Asia

The strain of cholera currently sweeping through post-earthquake Haiti originated in South Asia, conclude scientists who did a rapid genetic analysis of bacteria collected from Haitian patients. The finding supports the notion that the cholera bacteria fueling the outbreak arrived on the island via recent visitors.

13 Dec 2010

Pomegranate juice exhibits potential to prevent metastasis of prostate cancer cells to the bone

Researchers at the University of California, Riverside have identified components in pomegranate juice that both inhibit the movement of cancer cells and weaken their attraction to a chemical signal that promotes the metastasis of prostate cancer to the bone. The research could lead to new therapies for preventing cancer metastasis.

13 Dec 2010

Stem cell biology offers great hope for eventual repair of body parts

Remarkable progress in understanding how stem cell biology works has been reported by a team of leading scientists, directed by experts at UC Santa Barbara. Their research has been published in the journal Cell Stem Cell.

13 Dec 2010

Medical Science News

Beta-catenin protein plays a key role in development of stem cells in acute leukaemia

Diet linked to onset of mental illness

Reversible two-step binding mechanism to stop cancer cell growth

Study finds expression of toxic RNA that leads to Fragile X Tremor Ataxia Syndrome modifiable

Osteoporosis drug reduces bone loss in oral cancer

Mouse study shows flu virus infection may protect against asthma

Drug to reverse immunological decline in aging

Novel labeling technique helps researchers to explore DNA chemical modification

BUSM professor wins 2010 Van Slyke Award for seminal contributions to laboratory medicine

FOXA1 gene controls oestrogen-fuelled growth of breast cancer cells

New osteoporosis drug appears to reduce bone loss in mice with oral cancer

University of Utrecht orders for Bruker 527 GHz Solid State DNP-NMR system

Cedarlane to distribute TGR's new ELISA-One technology assay reagents in Canada and the US

Inimex, SARomics Biostructures achieve scientific milestone in IMX942 IDR collaboration

Yissum introduces novel DNA profiling method for investigating complex crime scenes

Vical's Vaxfectin adjuvant boosts immune response of DNA-based vaccines against cancer

Scientists create functioning human intestinal tissue from pluripotent stem cells

Origin of Haiti cholera epidemic traced to South Asia

Pomegranate juice exhibits potential to prevent metastasis of prostate cancer cells to the bone

Stem cell biology offers great hope for eventual repair of body parts

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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