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RA synthetic derivative 4-HPR's ability to induce tumour cell death

Retinoic acid (RA), a natural derivative of vitamin A, is the basis of a number of treatments against cancer. Nevertheless, it has certain disadvantages, such as the possibility of the appearance of retinoic acid syndrome, present in 25 % of cases and which can lead to death. The development of 4-HPR, a synthetic derivative of RA, has meant a considerable advance due to its greater efficacy compared to its predecessor.

7 Sep 2010

FDA grants IRIS clearance for analysis of synovial fluid with iQ200, iRICELL automated microscopy analyzers

IRIS International, Inc., a leading manufacturer of automated in-vitro diagnostic systems and consumables for use in hospitals and commercial laboratories worldwide and provider of high value personalized diagnostics testing services through its CLIA certified molecular diagnostics laboratory, today announced that it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for the analysis of synovial fluid as a new product application in its Body Fluids Module utilizing its iQ®200 and iRICELL® automated microscopy analyzers.

7 Sep 2010

Research suggests blocking HMGB1 protein can benefit cancer patients

Like some people, cells eat when they are under pressure-but they consume parts of themselves. A multi-function protein helps control this form of cannibalism, according to a study in the September 6 issue of the Journal of Cell Biology.

7 Sep 2010

Physical qualities can influence stem cell differentiation mechanism: Research

A researcher at the Hebrew University of Jerusalem, together with Israeli and foreign collaborators, has revealed how physical qualities and not only chemical ones may have an influence in determining how adult stem cells from the bone marrow develop into differentiated ones. This represents an important step in understanding the mechanisms that direct and regulate the specialization of stem cells from their undefined state.

7 Sep 2010

International Iberian Nanotechnology Laboratory orders for Vistec's EBPG5200 electron-beam lithography system

Vistec Lithography, a leading supplier of advanced electron-beam lithography systems has announced today that the International Iberian Nanotechnology Laboratory (INL) in Braga, Portugal has placed an order for Vistec's electron-beam lithography system EBPG5200. The Portuguese Laboratory is the first fully international research organization in Europe in the field of nanoscience and nanotechnology.

7 Sep 2010

Researchers to develop new treatment strategy for cancer

Cancer is a difficult disease to treat because it's a personal disease. Each case is unique and based on a combination of environmental and genetic factors. Conventional chemotherapy employs treatment with one or more drugs, assuming that these medicines are able to both "diagnose" and "treat" the affected cells. Many of the side effects experienced by chemotherapy patients are due to the fact that the drugs they are taking aren't selective enough.

7 Sep 2010

Researchers decode words from brain signals in paralyzed people

In an early step toward letting severely paralyzed people speak with their thoughts, University of Utah researchers translated brain signals into words using two grids of 16 microelectrodes implanted beneath the skull but atop the brain. "We have been able to decode spoken words using only signals from the brain with a device that has promise for long-term use in paralyzed patients who cannot now speak," says Bradley Greger, an assistant professor of bioengineering.

7 Sep 2010

Chemicals in non-stick cookware elevates cholesterol level among children: Report

Children and teens with higher blood levels of chemicals used in the production of non-stick cookware and waterproof fabrics appear more likely to have elevated total and LDL cholesterol levels, according to a report in the September issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

7 Sep 2010

Unpredictable food poisoning

While we are often exposed to bacteria in our food which could cause food poisoning, we don't always become ill - why should this be so?

6 Sep 2010

Plaque-causing bacteria increases risk of heart attack

Plaque-causing bacteria can jailbreak from the mouth into the bloodstream and increase your risk of heart attack says a scientist at the Society for General Microbiology's autumn meeting in Nottingham.

6 Sep 2010

Gene containing 'minisatellite' plays key role in driving human DNA diversity

One of the key drivers of human evolution and diversity, accounting for changes that occur between different generations of people, is explained by new research published today (Sept 5) by world-renowned scientist Professor Sir Alec Jeffreys, who discovered DNA fingerprinting at the University of Leicester.

6 Sep 2010

2010 Mainz University Meeting to focus Interdisciplinary Neurosciences

The 2010 Meeting of the Mainz University Research Focus on Interdisciplinary Neurosciences will be held on "Cognitive Enhancement Ethics and Society".

4 Sep 2010

Kavli Day 2010 at Norwegian University of Science and Technology

In celebration of Kavli Prize Week, the Norwegian University of Science and Technology (NTNU), the Norwegian Academy of Science and Letters, and the Kavli Foundation will hold a series of lectures and events on 9 September 2010 in Trondheim, Norway at the NTNU campus. The event features a number of 2010 Kavli Prize Laureates. The festivities continue after the official celebration, with two symposia sponsored by NTNU, one in neuroscience and one in nanoscience.

4 Sep 2010

Human endogenous retroviruses may provide insight evidence to HIV diagnosis

Why is it so hard to isolate and purify human immunodeficiency virus (HIV).Why has no one been able to see, by electron microscopy, a single HIV particle in the blood of AIDS patients, even those who have a "high viral load" Why does HIV seem to mutate with startling rapidity. AIDS researchers have not been able to come up with answers to these questions.

4 Sep 2010

Single-dose of experimental malaria drug clears parasites in mice, represents potential new class of drugs to treat malaria in humans

An experimental malaria drug was shown to effectively treat the disease in mice with only a single dose, according to a study published Thursday in the journal Science, Reuters reports (Kelland, 9/2). The new drug, known as NITD609, "represents an entirely new class of medicines to treat malaria ... Human trials, backed by Swiss pharmaceutical giant Novartis AG, could begin later this year," the Wall Street Journal writes (Naik, 9/3).

4 Sep 2010

New insight into abnormalities in cancer cells

A basic requirement for growth and life of a multicellular organism is the ability of its cells to divide. Chromosomes in the cells duplicate and are then distributed among the daughter cells. This distribution is organized by a protein complex made up of several hundred different proteins, called the centrosome. In cancer cells, the centrosome often assumes an unnatural shape or is present in uncontrolled numbers. The reasons for this were previously largely unknown.

4 Sep 2010

Researchers to study protein fragments released into bloodstream after heart attack

A blood test to diagnose which heart attack survivors will suffer heart failure is the goal of a new five-year, $11.6 million contract to the UT Health Science Center San Antonio from the National Heart, Lung, and Blood Institute (NHLBI).

4 Sep 2010

Colo. lawmaker pushes bill to permit stem cell research

Politico reports that as "Congress prepares to return for a limited pre-election agenda, Rep. Diana DeGette (D-Colo.) said she has picked up wide support for her bill to permit embryonic stem-cell research and expects it will pass this month. Although it has been strongly opposed by anti-abortion activists, she voiced confidence that the measure will be a political boost for its backers as well as good policy.

4 Sep 2010

Researchers reveal new details on bacterial cannibalism

Researchers at the University of California, San Diego have revealed new details about how cannibalistic bacteria identify peers suitable for consumption. The work, which employed imaging mass spectrometry, is a first step toward a broader effort to map all signaling molecules between organisms.

4 Sep 2010

Maryland Stem Cell Research Commission partners with NIH, NIST to host symposium on stem cell research

The Maryland Stem Cell Research Commission will host the Third Annual Maryland Stem Cell Research Symposium in partnership with the National Institutes of Health and the National Institute of Standards and Technology on Wednesday, Sept. 22, 2010.

4 Sep 2010