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Amorfix Life Sciences uses A(4) test to detect accumulation of Abeta in mouse models of AD

Amorfix Life Sciences, a company focused on treatments and diagnostics for misfolded protein diseases including Alzheimer's disease, has used its A(4) test to compare the rate of accumulation of aggregated Abeta in the brain tissue of various mouse models of AD. Amorfix presented this new data at the International Conference on Alzheimer's Disease this week.

13 Jul 2010

Biodel reports preclinical test results of BIOD620 glucose-regulated or "smart" basal insulin product candidate

Biodel Inc. today reported results of preclinical tests which demonstrated the potential of the company's glucose-regulated or "smart" basal insulin product candidate, BIOD620, to release insulin proportionally in response to changing glucose conditions. In an oral presentation today at the 37th Annual Meeting and Exposition of the Controlled Release Society in Portland, Oregon, Nandini Kashyap, director of novel drug delivery at Biodel, described results of in vitro and in vivo studies with diabetic pigs which compared the use of BIOD620 to Lantus® (insulin glargine).

13 Jul 2010

New study on impact of bortezomib on mantle cell lymphoma

A new study by researchers from the John Theurer Cancer Center at Hackensack University Medical Center sheds light on how bortezomib (VELCADE-), the first in a new class of cancer drugs known as proteasome inhibitors, works in mantle cell lymphoma. The study also provides preliminary evidence for which patients might benefit most from bortezomib.

13 Jul 2010

Stem cell transplantation from healthy donor helps cure aggressive form of CLL

The transplantation of stem cells from a healthy donor (allogeneic) offers the chance of cure for patients with an aggressive form of chronic lymphocytic leukemia (CLL), irrespective of genetic prognostic factors and the prior course of the disease. The German CLL Study Group proved this in a multicentric clinical phase II study led by Professor Dr. Peter Dreger, senior consultant and head of the division of stem cell transplantation at the Department of Internal Medicine V at Heidelberg University Hospital.

13 Jul 2010

GWAS suggests genetic variant with increased oncogene expression for cancer study

The study, published July 13th in Genome Research, showcases a new protocol for studying the activity of cancer-risk variants suggested by GWAS studies. The results also underscore the dramatic consequences of small genetic changes even in the vast stretches of DNA, known as "gene deserts," that do not code for proteins.

13 Jul 2010

Early markers for metabolic syndrome in youth

Melinda Sothern, PhD, CEP, Professor of Public Health and Director of Health Promotion at LSU Health Sciences Center New Orleans, will present evidence that supports relationships seen in adolescents between insulin sensitivity and fatty liver, belly fat, and total body fat and identifies additional potential early markers of insulin resistance and metabolic syndrome in healthy 7-9 year-old children, including fat in muscle cells, blood pressure, physical activity, and birth weight.

13 Jul 2010

Soy reduces weight gain in post-menopausal female rats

Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, finds that a diet rich in soy prevents weight gain in post-menopausal female rats.

13 Jul 2010

CSHL scientists reverse symptoms of Type III SMA using ASOs

The devastating, currently incurable motor-neuron disease spinal muscular atrophy might soon be treated with tiny, chemically modified pieces of RNA called antisense oligonucleotides.

13 Jul 2010

Researchers examine impact of genetic ancestry on measures of lung function

Americans with lung disease may face a far greater level of lung damage than either they or their doctor suspect, depending on their individual genetic heritage, according to research published online July 7 in the New England Journal of Medicine. The research implications range from diagnosing the severity of asthma, to disability decisions or eligibility for lung transplants, researchers say.

13 Jul 2010

Food portion control is a matter of perception, suggests study

Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, suggests that the key to losing weight could lie in manipulating our beliefs about how filling we think food will be before we eat it, suggesting that portion control is all a matter of perception.

13 Jul 2010

Researchers identify genetic variant associated with increased risk of AAA

Geisinger researchers are part of an international team that has identified a genetic variant more common in individuals with abdominal aortic aneurysms. This is one of the largest studies ever into the genetics of AAA. The results of the work will appear in this week's online edition of Nature Genetics.

13 Jul 2010

Vivakor expands distribution channels of VivaThermic vials

Vivakor, Inc. announced that it has expanded United States distribution of its VivaThermic vials. A listing of Authorized Distributors of VivaThermic vials is available at www.vivathermic.com/distributors.

13 Jul 2010

Researchers discover gene mutation that causes auditory neuropathy

Researchers have identified a gene mutation that causes a rare form of hearing loss known as auditory neuropathy, according to U-M Medical School scientists. In the study published online today in the Proceedings of the National Academy of Sciences USA, U-M's Marci Lesperance, M.D., and Margit Burmeister, Ph.D. led a team of researchers who examined the DNA of individuals from the same large family afflicted with the disorder.

13 Jul 2010

AnaptysBio awarded DARPA contract to generate novel high affinity thermally stable antibodies

AnaptysBio, Inc., a privately-held therapeutic antibody platform and product company, today announced it has been awarded a contract by the Defense Advanced Research Projects Agency (DARPA), to use its proprietary somatic hypermutation (SHM) technology platform to generate novel high affinity thermally stable antibodies that could be used by the military in antibody-based biosensors, including those that can detect bioterrorist threats.

13 Jul 2010

$Binge-drinking teenagers at risk for future osteoporosis, bone fractures$

Binge-drinking teenagers at risk for future osteoporosis, bone fractures

Binge-drinking teenagers may be putting themselves at risk for future osteoporosis and bone fractures, according to researchers at Loyola University Health System.

13 Jul 2010

Jellyfish protein may help cognitive function in Alzheimer’s

Quincy Bioscience, a research-based biotechnology company, is attending the annual Alzheimer’s Association International Conference on Alzheimer’s Disease (ICAD) sharing promising interim data from the Madison Memory Study, a randomized controlled trial, which shows the jellyfish protein apoaequorin improves cognitive function in individuals with memory concerns.

13 Jul 2010

Research findings could offer new approach to diabetes therapy, nutrition experts say

Nutrition experts at Oregon State University have essentially "cured" laboratory mice of mild, diet-induced diabetes by stimulating the production of a particular enzyme. The findings could offer a new approach to diabetes therapy, experts say, especially if a drug could be identified that would do the same thing, which in this case was accomplished with genetic manipulation.

13 Jul 2010

Study explores direct role of FTO gene on Alzheimer's and dementia risk in old age

A gene known as FTO, which appears to be correlated with obesity in humans, may also increase risk of Alzheimer's disease and dementia, according to new research presented today at the Alzheimer's Association International Conference on Alzheimer's Disease 2010 in Honolulu, HI. And when a person has certain variants of both FTO and a recognized Alzheimer's risk gene known as APOE, the risk of Alzheimer's could be doubled.

13 Jul 2010

Scientists discover way to enhance nerve regeneration in peripheral nervous system

Faculty of Medicine scientists have discovered a way to enhance nerve regeneration in the peripheral nervous system. This important discovery could lead to new treatments for nerve damage caused by diabetes or traumatic injuries. Peripheral nerves connect the brain and spinal cord to the body, and without them, there is no movement or sensation. Peripheral nerve damage is common and often irreversible. This discovery is published in the July 7, 2010 edition of the Journal of Neuroscience.

12 Jul 2010

Accumetrics, Daiichi Sankyo, Eli Lilly collaborate to raise awareness about antiplatelet therapy

Accumetrics, Inc., Daiichi Sankyo, Inc, and Eli Lilly and Company announced today that the companies have entered into a strategic collaboration in the United States to raise awareness about antiplatelet therapy and the role of platelet function testing.

12 Jul 2010

Medical Science News

Amorfix Life Sciences uses A(4) test to detect accumulation of Abeta in mouse models of AD

Biodel reports preclinical test results of BIOD620 glucose-regulated or "smart" basal insulin product candidate

New study on impact of bortezomib on mantle cell lymphoma

Stem cell transplantation from healthy donor helps cure aggressive form of CLL

GWAS suggests genetic variant with increased oncogene expression for cancer study

Early markers for metabolic syndrome in youth

Soy reduces weight gain in post-menopausal female rats

CSHL scientists reverse symptoms of Type III SMA using ASOs

Researchers examine impact of genetic ancestry on measures of lung function

Food portion control is a matter of perception, suggests study

Researchers identify genetic variant associated with increased risk of AAA

Vivakor expands distribution channels of VivaThermic vials

Researchers discover gene mutation that causes auditory neuropathy

AnaptysBio awarded DARPA contract to generate novel high affinity thermally stable antibodies

Binge-drinking teenagers at risk for future osteoporosis, bone fractures

Jellyfish protein may help cognitive function in Alzheimer’s

Research findings could offer new approach to diabetes therapy, nutrition experts say

Study explores direct role of FTO gene on Alzheimer's and dementia risk in old age

Scientists discover way to enhance nerve regeneration in peripheral nervous system

Accumetrics, Daiichi Sankyo, Eli Lilly collaborate to raise awareness about antiplatelet therapy

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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