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Identification and elimination of cancer stem cells

A new field of cancer research could explain why some cancers that appear to have been cured can rear their ugly head or spread to other organs.

3 Apr 2010

Study: Trial vaccine eliminates residual cancer cells in CML patients

Johns Hopkins Kimmel Cancer Center researchers say preliminary studies show that a vaccine made with leukemia cells may be able to reduce or eliminate the last remaining cancer cells in some chronic myeloid leukemia (CML) patients taking the drug Imatinib mesylate (Gleevec).

3 Apr 2010

Notch pathway may be a good target for drug development, study says

Working with mice, Johns Hopkins scientists who tested drugs intended to halt growth of brain cancer stem cells -- a small population of cells within tumors that perpetuate cancer growth -- conclude that blocking these cells may be somewhat effective, but more than one targeted drug attack may be needed to get the job done.

3 Apr 2010

Study could aid in developing new, effective treatments for prostate cancer

Van Andel Research Institute (VARI) scientists have determined how two proteins required for the initiation and development of prostate cancer interact at the molecular level, which could lead to improved treatments for the disease.

3 Apr 2010

Radius Health to develop lightweight X-ray emitter employing MAX technology at UCLA incubator space

While today many medical-imaging needs are being met with traditional vacuum tube-based technology, large segments of the X-ray-imaging market are poorly served, and there is widespread demand for both performance improvements and cost reductions.

3 Apr 2010

Study uses hESC to derive floor plate tissue

New York Stem Cell Foundation (NYSCF) Fellow, Christopher Fasano, PhD, of the New York Neural Stem Cell Institute, is lead author on a study that investigating human neural development. Dr. Fasano conducted this work while working as a post-doctoral fellow at Memorial Sloan Kettering Cancer Center in the lab of Dr. Lorenz Studer.

3 Apr 2010

Kinetics of T cell receptors: New findings could lead to reevaluation of earlier conclusions

T cell receptors are among the most important molecules in the immune system because of their role in recognizing the antigens that signal such threats as viruses and cancer. The receptors must also distinguish these threats from the body's own cells to avoid triggering an unwanted immune system response.

3 Apr 2010

Researchers explore microbial infection of human cells in space environment

In a first-of-its-kind experiment, the unique conditions of spaceflight will be used to examine how cells remain healthy or succumb to disease, particularly in the face of stress or damage.

3 Apr 2010

Harnessing body's own natural killer cells to battle cancer in children

Work underway at St. Jude Children's Research Hospital seeks to harnesses the body's own immune cells known as natural killer, or NK, cells to help children battle cancer. NK cells are the immune system's warriors. The cells circulate widely in the body, armed with proteins, called enzymes, capable of delivering a deadly one-two punch to viruses and cancer cells.

3 Apr 2010

New production method yields hundredsfold more ubiquitylated proteins critical for cancer research

Scientists at the University of Delaware have developed a new method for producing proteins critical to research on cancer, Alzheimer's, and other diseases.

3 Apr 2010

Scientists provide first-ever glimpse of HIV protein structure

Scientists from the California Institute of Technology (Caltech) have provided the first-ever glimpse of the structure of a key protein-gp120-found on the surface of a specific subgroup of the human immunodeficiency virus, HIV-1.

3 Apr 2010

Winner of 2010-2011 Luminex/ACMGF Award

The American College of Medical Genetics Foundation (ACMGF) has awarded Dr. Marilyn M. Li, of the Tulane Medical Center and the Tulane University School of Medicine the 2010-2011 Luminex/ACMGF Award at the ACMG 2010 Annual Clinical Genetics Meeting in Albuquerque, NM.

From Luminex 3 Apr 2010

Beike Biotechnology awarded ISO9001 certification for implementation of comprehensive QMS

Beike Biotechnology Co. Ltd., one of the world's leading biotechnology companies focusing on adult stem cell therapies, has been awarded ISO9001 certification by the International Organization for Standardization ("ISO"). This internationally recognized designation signifies Beike has established a Quality Management System (QMS) that complies with ISO9001 standards.

3 Apr 2010

"Mouse model" study finds LRRK2 gene mutation may cause inherited Parkinson's disease

Using new one-of-a-kind "mouse models" that promise to have a significant impact on future Parkinson's disease research, Mount Sinai School of Medicine researchers are among the first to discover how mutations in a gene called LRRK2 may cause inherited (or "familial") Parkinson's disease, the most common form of the disease.

2 Apr 2010

DNA patent case: US District Judge rules in favor of AMP

The Association for Molecular Pathology (AMP) is an international medical and professional association representing approximately 1,800 physicians, doctoral scientists, and medical laboratory scientists who perform laboratory testing based on knowledge derived from molecular biology, genetics, and genomics. AMP applauds US District Judge Robert Sweet's ruling in favor of the plaintiffs in the lawsuit, Association for Molecular Pathology, et al. v. U.S. Patent and Trademark Office, et al.

2 Apr 2010

Variant of ATG16L1 gene associated with higher risk for Crohn's disease

The ATG16L1 gene is located on chromosome 2 and encodes a protein involved in the formation of autophagosomes during autophagy. Autophagy is a cytoplasmic process that keeps a cell stable. Hampe et al first identified ATG16L1 as a Crohn's disease (CD) susceptibility gene in 2007, and many other studies have arisen since then. However, the definite relationship of variants of ATG16L1 with IBD remains unclear.

2 Apr 2010

Genome of Australian zebra finch decoded

Nearly all animals make sounds instinctively, but baby songbirds learn to sing in virtually the same way human infants learn to speak: by imitating a parent.

2 Apr 2010

RPCI studies potential of CellSearch test for monitoring treatment results in metastatic gallbladder patients

Renuka Iyer, MD, of the Department of Medicine, and Dan Iancu, MD, of the Department of Pathology and Laboratory Medicine at Roswell Park Cancer Institute (RPCI) are studying how a new test called CellSearch could be used with standard radiographic methods to monitor treatment results in patients with locally advanced or metastatic gallbladder or biliary duct cancers. The goal of the study is to see if CellSearch could predict patient response to therapy earlier than traditional measures.

2 Apr 2010

Nanotechnology for eavesdropping on inner electrical activity of individual cells

A nanometer-scale probe designed to slip into a cell wall and fuse with it could offer researchers a portal for extended eavesdropping on the inner electrical activity of individual cells.

2 Apr 2010

Cyclacel Pharmaceuticals' abstracts on cell cycle inhibitor drugs selected for presentation at AACR meeting

Cyclacel Pharmaceuticals, Inc. today announced that six abstracts highlighting translational and preclinical data for Cyclacel's cell cycle inhibitor drugs have been selected for presentation at the American Association of Cancer Research (AACR) Annual Meeting, being held from April 17-21, 2010, in Washington, DC.

2 Apr 2010

Medical Science News

Identification and elimination of cancer stem cells

Study: Trial vaccine eliminates residual cancer cells in CML patients

Notch pathway may be a good target for drug development, study says

Study could aid in developing new, effective treatments for prostate cancer

Radius Health to develop lightweight X-ray emitter employing MAX technology at UCLA incubator space

Study uses hESC to derive floor plate tissue

Kinetics of T cell receptors: New findings could lead to reevaluation of earlier conclusions

Researchers explore microbial infection of human cells in space environment

Harnessing body's own natural killer cells to battle cancer in children

New production method yields hundredsfold more ubiquitylated proteins critical for cancer research

Scientists provide first-ever glimpse of HIV protein structure

Winner of 2010-2011 Luminex/ACMGF Award

Beike Biotechnology awarded ISO9001 certification for implementation of comprehensive QMS

"Mouse model" study finds LRRK2 gene mutation may cause inherited Parkinson's disease

DNA patent case: US District Judge rules in favor of AMP

Variant of ATG16L1 gene associated with higher risk for Crohn's disease

Genome of Australian zebra finch decoded

RPCI studies potential of CellSearch test for monitoring treatment results in metastatic gallbladder patients

Nanotechnology for eavesdropping on inner electrical activity of individual cells

Cyclacel Pharmaceuticals' abstracts on cell cycle inhibitor drugs selected for presentation at AACR meeting

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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