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Study explores prognostic biomarkers in patients with lymph node-negative colorectal cancer

Tumor budding at the invasive tumor front of colorectal cancer is recognized as an independent prognostic factor significantly related to both lymph node and distant metastasis.

5 Mar 2010

Researchers discuss the synergy between nanoscience and neuroscience

Is it possible to build supercomputers that can replicate the human brain, or to develop nanotechnology that can lead to an implantable chip for interfacing with neurons and other types of cellular networks?

5 Mar 2010

Gluten intolerance: Hereditary risk factors and link to virus infections

A research project in the Academy of Finland's Research Programme on Nutrition, Food and Health (ELVIRA) has brought new knowledge on the hereditary nature of gluten intolerance and identified genes that carry a higher risk of developing the condition. Research has shown that the genes in question are closely linked with the human immune system and the occurrence of inflammations, rather than being connected with the actual breakdown of gluten in the digestive tract.

5 Mar 2010

Life Technologies, TGen, US Oncology collaborate to sequence genomes of triple negative breast cancer patients

Life Technologies Corporation today announced that it is collaborating with the Translational Genomics Research Institute and US Oncology to sequence the genomes of 14 patients afflicted with triple negative breast cancer whose tumors have progressed despite multiple other therapies.

5 Mar 2010

Genetic epidemiology: Importance of population genomics

Did women and men contribute equally to the lineage of contemporary populations? Did our ancestors, Homo sapiens, lean more toward polygamy or monogamy? To answer these questions, Dr. Damian Labuda, an investigator at the Sainte-Justine University Hospital Research Center and a professor at the Department of Pediatrics of the Universit- de Montr-al, headed a team that analyzed genomic data from three population samples of African, Asian and European origin. The study's findings are published in the most recent issue of the American Journal of Human Genetics.

5 Mar 2010

Predictive Biosciences to present its novel MADR approach during 2010 GU Symposium

Predictive Biosciences today announced that the Company will be presenting its novel Multi-Analyte Diagnostic Readout approach to the development of a non-invasive, urinary biomarker based assay for the detection of bladder cancer during the 2010 Genitourinary Cancers Symposium, being held March 5-7 in San Francisco.

5 Mar 2010

TLR's role in HIV-1 reactivation induced by periodontal pathogens

Today, during the 39th Annual Meeting of the American Association for Dental Research, convening at the Walter E. Washington Convention Center in Washington, DC, lead researcher O.A. Gonzalez (University of Kentucky, Lexington) will present a poster of a study titled "TLR2 and TLR9 Activation by Periodontal Pathogens induce HIV-1 Reactivation."

5 Mar 2010

Worm proteins may provide option in management of gastrointestinal inflammation in IBD patients

Patients with inflammatory bowel disease (IBD) suffer from chronic inflammation of the gut leading to gastrointestinal motility alterations with symptoms such as abdominal pain, cramps and diarrhea that profoundly affect their quality of life. The lack of exposure to worm infections, as a result of improved living standards and medical conditions, might have contributed to the increased incidence of IBD in the Western world.

5 Mar 2010

Endothelial cells can produce copious amounts of adult stem cells: Study

In a leap toward making stem cell therapy widely available, researchers at the Ansary Stem Cell Institute at Weill Cornell Medical College have discovered that endothelial cells, the most basic building blocks of the vascular system, produce growth factors that can grow copious amounts of adult stem cells and their progeny over the course of weeks.

5 Mar 2010

Signaling mechanisms responsible for HGF-induced CCA invasiveness: More insight

Cholangiocarcinoma (CCA), a bile duct cancer, is one of the major cancers in Northeast Thailand. This cancer is difficult to diagnose and has high metastatic and mortality rates. Overexpression of Met, a hepatocyte growth factor (HGF) receptor, has frequently been found in CCA and is correlated with progression of this type of cancer.

5 Mar 2010

Transcendental Meditation technique produces unique state of "restful alertness"

A new EEG study conducted on college students at American University found they could more highly activate the default mode network, a suggested natural "ground state" of the brain, during their practice of the Transcendental Meditation technique. This three-month randomized control study is published in a special issue of Cognitive Processing dedicated to the Neuroscience of Meditation and Consciousness, Volume 11, Number 1, February, 2010.

5 Mar 2010

HMS study suggests new targets for treating Angelman syndrome

Angelman Syndrome is a rare but serious genetic disorder that causes a constellation of developmental problems in affected children, including mental retardation, lack of speech, and in some cases, autism. Over a decade ago, researchers found that AS was caused by mutation in a single gene, but no one had been able to explain how this defect resulted in the debilitating neurological symptoms of the disease.

5 Mar 2010

Overview of nanotechnology: Nanoparticles may eventually be used in cosmetic products

The rapidly growing field of nanotechnology and its future use in cosmetic products holds both enormous potential and potential concern for consumers. Currently, major cosmetic manufacturers have imposed a voluntary ban on the use of nanoparticles in products while they await a ruling from the Food and Drug Administration regarding the safety of this technology.

5 Mar 2010

Gene involved in susceptibility and resistance to TB identified

University of Washington researchers have identified a gene involved in susceptibility and resistance to tuberculosis. This same gene, they have found, has a role in the severity of leprosy, which is caused by a related pathogen. The researchers also have learned why this gene is important for susceptibility.

5 Mar 2010

OSCC cells express VEGFR1, VEGFR2 and serve as targets and effectors for VEGF: Study

Today, during the 39th Annual Meeting of the American Association for Dental Research, convening at the Walter E. Washington Convention Center in Washington, DC, lead researcher M. Tong, The Ohio State University, will present a poster of a study titled "Epithelial-to-Endothelial Transition: An Epithelial Phenotypic Modulation Facilitating Oral-Squamous-Cell Carcinoma Progression."

5 Mar 2010

Advaxis' Listeria based fusion protein granted U.S. patent

The US Patent and Trademark Office (USPTO) has issued Advaxis, Inc.,, the live, attenuated Listeria monocytogenes (Listeria) immunotherapy company, patent #7662396 titled “Compositions and Methods for Enhancing the Immunogenicity of Antigens” for the use of fusion proteins that have been found to be effective in numerous models for the treatment of cancer in the presence of immune tolerance.

5 Mar 2010

Chikungunya: Experimental vaccine successfully tested in monkeys

Imagine a mosquito-borne virus that has already infected millions of people in recent outbreaks in South and Southeast Asia, the islands of the Indian Ocean, Africa and northern Italy. Although seldom fatal, it causes highly painful arthritis-like symptoms that can linger for months or even years. It's capable of adapting to spread through a mosquito species common in much of North America. And no vaccine or treatment exists to protect humans from its effects.

5 Mar 2010

Humacyte, Xcellerex collaborate to develop novel vascular graft for transplantation technologies

Humacyte, Inc. and Xcellerex, Inc. have entered into an initial strategic collaboration for Xcellerex to develop a novel manufacturing process that will enable the production of Humacyte’s lead regenerative medicine product using Xcellerex’s XDR single use bioreactor system in its FlexFactory®. Humacyte’s product is a large diameter vascular graft that is based on its innovative and proprietary platform technology for engineering human, extracellular matrix-based tissues that have properties that are similar to native tissues.

5 Mar 2010

Argos Therapeutics' AGS-004 immunotherapy for HIV demonstrates clinical and commercial potential

Argos Therapeutics today announced the publication of a manuscript in the February edition of Clinical Immunology, detailing positive immune response, safety and manufacturing data for its AGS-004 immunotherapy for HIV. AGS-004 is a product of the Company’s Arcelis™ technology, and is a personalized, RNA-loaded dendritic cell-based immunotherapy that is perfectly matched to each patient’s unique HIV viral burden. The manuscript details a clinical study in which AGS-004 was evaluated in type-1 HIV-infected adults who were being treated with antiretroviral therapy (ART).

5 Mar 2010

Study shows link between Vitamin D levels and basal cell carcinoma

A Henry Ford Hospital study has shown a link between Vitamin D levels and basal cell carcinoma, a finding that could lead researchers to better understand the development of the most common form of skin cancer.

5 Mar 2010

Medical Science News

Study explores prognostic biomarkers in patients with lymph node-negative colorectal cancer

Researchers discuss the synergy between nanoscience and neuroscience

Gluten intolerance: Hereditary risk factors and link to virus infections

Life Technologies, TGen, US Oncology collaborate to sequence genomes of triple negative breast cancer patients

Genetic epidemiology: Importance of population genomics

Predictive Biosciences to present its novel MADR approach during 2010 GU Symposium

TLR's role in HIV-1 reactivation induced by periodontal pathogens

Worm proteins may provide option in management of gastrointestinal inflammation in IBD patients

Endothelial cells can produce copious amounts of adult stem cells: Study

Signaling mechanisms responsible for HGF-induced CCA invasiveness: More insight

Transcendental Meditation technique produces unique state of "restful alertness"

HMS study suggests new targets for treating Angelman syndrome

Overview of nanotechnology: Nanoparticles may eventually be used in cosmetic products

Gene involved in susceptibility and resistance to TB identified

OSCC cells express VEGFR1, VEGFR2 and serve as targets and effectors for VEGF: Study

Advaxis' Listeria based fusion protein granted U.S. patent

Chikungunya: Experimental vaccine successfully tested in monkeys

Humacyte, Xcellerex collaborate to develop novel vascular graft for transplantation technologies

Argos Therapeutics' AGS-004 immunotherapy for HIV demonstrates clinical and commercial potential

Study shows link between Vitamin D levels and basal cell carcinoma

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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