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NIMH awards SRI International a $6.3M contract for study of ligands for brain imaging research

SRI International, an independent nonprofit research and development organization, announced today that it has been awarded a $6.3 million contract by the National Institute of Mental Health (NIMH) to conduct preclinical safety studies of promising novel ligands that will be used for brain imaging research and clinical applications.

6 Oct 2009

Promising alternative to use of live animals for drug testing

International Stem Cell Corporation, the first company to perfect a method of creating human “parthenogenetic” stem cells from unfertilized eggs, announces positive results of its collaboration with Absorption Systems to study ISCO’s stem-cell-derived human corneal tissue as an alternative to live animals for drug testing.

6 Oct 2009

Study reveals information about molecular structure of prions

A collaboration between scientists at Vanderbilt University and the University of California, San Francisco has led to the first direct information about the molecular structure of prions. In addition, the study has revealed surprisingly large structural differences between natural prions and the closest synthetic analogs that scientists have created in the lab.

6 Oct 2009

UCSF's Elizabeth Blackburn receives Nobel Prize in Medicine, lauded by Speaker Nancy Pelosi

Speaker Nancy Pelosi issued the following statement congratulating molecular biologist Elizabeth H. Blackburn of the University of California, San Francisco, who today was named to receive the 2009 Nobel Prize in Medicine. Dr. Blackburn shares the award with Carol W. Greider of Johns Hopkins University School of Medicine and Jack W. Szostak of Harvard Medical School for their discovery of an enzyme that plays a key role in normal cell function, as well as in cell aging and most cancers.

6 Oct 2009

Gene therapy to improve ailing heart's contractions of muscle cells

Scientists from the Universities of Michigan and Minnesota show in a research report published online in the FASEB Journal (http://www.fasebj.org) that gene therapy may be used to improve an ailing heart's ability to contract properly. In addition to showing gene therapy's potential for reversing the course of heart failure, it also offers a tantalizing glimpse of a day when "closed heart surgery" via gene therapy is as commonly prescribed as today's cocktail of drugs.

6 Oct 2009

New study to boost immune cells for pathogen resistance and vaccine efficacy in elderly

A new study from the Trudeau Institute in Saranac Lake, New York, demonstrates that immune system cells important for both pathogen resistance and vaccine efficacy live longer in older animals but because of this longevity acquire functional defects. The work may provide new targets for boosting immune system function in older individuals.

6 Oct 2009

Key defence mechanism used by the immune system against Listeria identified

A team of University of British Columbia microbiologists has identified a key defence mechanism used by the immune system against Listeria with strong implications for the future development of vaccines.

6 Oct 2009

Researchers identify that KLF17 gene with Id1 gene can regulate breast cancer metastasis

Researchers at The Wistar Institute have identified a key gene (KLF17) involved in the spread of breast cancer throughout the body. They also demonstrated that expression of KLF17 together with another gene (Id1) known to regulate breast cancer metastasis accurately predicts whether the disease will spread to the lymph nodes.

6 Oct 2009

Absence of certain proteins for proper cell duplication can lead to cancer

A Purdue University researcher has discovered that the absence of certain proteins needed for proper cell duplication can lead to cancer.

6 Oct 2009

Scientists identify new interference method to target cancer cells

Professor Jo Milner and Dr Shafiq Ahmed, from the YCR P53 Research Unit in the Department of Biology, used a process called RNA interference to target the JNK2 gene in both cancer and healthy cells. The cancer cells died but the healthy cells were unaffected.

6 Oct 2009

IBM scientists to build nanoscale DNA sequencer to read human DNA

In an effort to build a nanoscale DNA sequencer, IBM scientists are drilling nano-sized holes in computer-like chips and passing DNA strands through them in order to read the information contained within their genetic code.

6 Oct 2009

Molecular biologist receives 2009 Nobel Prize in Physiology or Medicine

Molecular biologist Elizabeth H. Blackburn, PhD, 60, of the University of California, San Francisco, today was named to receive the 2009 Nobel Prize in Physiology or Medicine.

6 Oct 2009

New journal on cancer biology and genetics

SAGE announces Genes & Cancer, a monthly journal edited by Dr. Prem Reddy, founder and previous Editor-in-Chief of the prestigious and highly-ranked Oncogene.

6 Oct 2009

ALS patients' bone marrow cells capable of differentiating into nerve-supporting cells

BrainStorm Cell Therapeutics Inc., a leading developer of adult stem cell technologies and therapeutics, announced today that bone marrow cells taken from ALS patients were capable of differentiating into nerve-supporting cells.

5 Oct 2009

Pharmacogenomics Centre deploys the Isilon IQ to accelerate its next-generation genetic sequencing operations

Isilon® Systems (Nasdaq: ISLN), the proven leader in scale-out NAS, today announced that Pharmacogenomics Centre, a partnership between Genome Quebec and the Montreal Heart Institute focused on enhancing new and existing drug development research programs through the inclusion of genetic information, has deployed Isilon IQ to accelerate its next-generation genetic sequencing operations.

5 Oct 2009

Elizabeth Blackburn, Carol Greider and Jack Szostak receive 2009 Nobel Prize in medicine

The 2009 Nobel Prize in medicine has been awarded to Elizabeth Blackburn, Carol Greider and Jack Szostak for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase.

5 Oct 2009

Inovio's SynCon H1N1 achieves protective antibody response against pandemic influenza in ferrets

Inovio Biomedical Corporation, a leader in DNA vaccine design, development and delivery, announced today that a combination of its synthetic consensus (SynConTM) H1N1 influenza vaccine candidates achieved protective antibody responses against the novel pandemic influenza A/H1N1 (2009) in 100% of tested ferrets.

5 Oct 2009

Myocardial and neurological effects of Tβ4 presented

REGENERX BIOPHARMACEUTICALS, INC. today reported on the results of several important research programs with Thymosin beta 4 (Tβ4) presented at the Second International Symposium on Thymosins in Health and Disease, in Catania, Italy.

5 Oct 2009

Scientists uncover the role of first-responder molecule involved in repairing DNA strand breaks

Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory and the Scripps Research Institute have uncovered the role played by the least-understood part of a first-responder molecule that rushes in to bind and repair breaks in DNA strands, a process that helps people avoid cancer.

5 Oct 2009

Study identifies new genes associated with head and neck cancer

A Henry Ford Hospital study has identified 231 new genes associated with head and neck cancer, one of the most deadly cancers responsible for 2.1 percent of all cancer deaths in the United States.

5 Oct 2009

Medical Science News

NIMH awards SRI International a $6.3M contract for study of ligands for brain imaging research

Promising alternative to use of live animals for drug testing

Study reveals information about molecular structure of prions

UCSF's Elizabeth Blackburn receives Nobel Prize in Medicine, lauded by Speaker Nancy Pelosi

Gene therapy to improve ailing heart's contractions of muscle cells

New study to boost immune cells for pathogen resistance and vaccine efficacy in elderly

Key defence mechanism used by the immune system against Listeria identified

Researchers identify that KLF17 gene with Id1 gene can regulate breast cancer metastasis

Absence of certain proteins for proper cell duplication can lead to cancer

Scientists identify new interference method to target cancer cells

IBM scientists to build nanoscale DNA sequencer to read human DNA

Molecular biologist receives 2009 Nobel Prize in Physiology or Medicine

New journal on cancer biology and genetics

ALS patients' bone marrow cells capable of differentiating into nerve-supporting cells

Pharmacogenomics Centre deploys the Isilon IQ to accelerate its next-generation genetic sequencing operations

Elizabeth Blackburn, Carol Greider and Jack Szostak receive 2009 Nobel Prize in medicine

Inovio's SynCon H1N1 achieves protective antibody response against pandemic influenza in ferrets

Myocardial and neurological effects of Tβ4 presented

Scientists uncover the role of first-responder molecule involved in repairing DNA strand breaks

Study identifies new genes associated with head and neck cancer

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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