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First genome-wide screen for protein complexes is completed

Researchers in Germany have finished the first complete analysis of the "molecular machines" in one of biology's most important model organisms: S. cerevisiae (baker's yeast). The study from the biotechnology company Cellzome, in collaboration with the European Molecular Biology Laboratory (EMBL), appears in this week's online edition of Nature.

23 Jan 2006

Nanocontainers show drug delivery potential

Tiny chemical cages created by researchers at Rutgers, The State University of New Jersey, show potential for delivering drugs to organs or tissues where they're needed without causing harm elsewhere.

18 Jan 2006

Cloned stem cells are perfectly normal

Scientists generally agree that all cloned animals are biologically flawed. But they don't agree about what that means for stem cells derived from cloned embryos, the basis for therapeutic cloning.

18 Jan 2006

Scientists design a fluorescent sensor capable of measuring intracellular acidity

The colouring agents traditionally used to stain organic tissues are no longer sufficient to meet today’s needs. The study of cell metabolism can only advance with better tools than those currently available.

16 Jan 2006

Genetic fingerprint unmasks microbial vandals

For the first time DNA analysis can identify paper-degrading microorganisms.

16 Jan 2006

Sickle cell corrected with gene copy

Scientists in the U.S. say they have found a way to use embryonic stem cells to correct the mutation that causes sickle cell disease in mice.

16 Jan 2006

Giant protein titin helps build muscles

Imagine grabbing two snakes by the tail so that they can't wriggle off in opposite directions. Scientists at the Hamburg Outstation of the European Molecular Biology Laboratory (EMBL) and collaborators from King's College in London have now discovered that something similar happens to a protein that is crucial in the formation of muscle tissue.

11 Jan 2006

Slow human evolution revealed by worm genome

Humans have retained genomic characteristics of a very ancient ancestor that have been lost in simpler animals such as the fly, indicating that humans are one of the most slowly evolving species. This is the finding of an international team of scientists including Dr David Ferrier of Oxford’s Department of Zoology published in a recent edition of the journal Science.

10 Jan 2006

AIDS drugs from sunflowers

Sunflowers can produce a substance which prevents the AIDS pathogen HIV from reproducing, at least in cell cultures. This is the result of research carried out by scientists at the University of Bonn in cooperation with the caesar research centre.

9 Jan 2006

Clever ants may hold the secret to antibiotic resistance

New research has revealed that ants that tend and harvest gardens of fungus carry on their bodies a secret weapon, an antibiotic-producing bacteria, which works against the parasites that invade their crops.

9 Jan 2006

Scientists describe phenomenon in the human genome called transcription-induced chimerism

In the January issue of the journal Genome Research, two teams of scientists describe a widespread phenomenon in the human genome called transcription-induced chimerism (TIC), where two adjacent genes produce a single, fused RNA transcript.

6 Jan 2006

New human embryonic stem cells grown in animal cell-free cultures

Scientists working at the WiCell Research Institute, a private laboratory affiliated with the University of Wisconsin-Madison, have developed a precisely defined stem cell culture system free of animal cells and used it to derived two new human embryonic stem cell.

2 Jan 2006

Study finds two genes that are essential for the proper development of muscle

Scientists at the University of North Carolina at Chapel Hill have found two genes that are essential for the proper development of muscle.

30 Dec 2005

Study finds two genes that are essential for the proper development of muscle

Scientists at the University of North Carolina at Chapel Hill have found two genes that are essential for the proper development of muscle.

30 Dec 2005

Gene discovery may reinvigorate the body's immune system after fighting viral infections

Like boxers wearied by a 15-round bout, the immune system's CD8 T cells eventually become "exhausted" in their battle against persistent viral infection, and less effective in fighting the disease.

29 Dec 2005

Scientists discover how to integrate new neurons into the brain

In experiments with mice, scientists from Johns Hopkins' Institute for Cell Engineering have discovered the steps required to integrate new neurons into the brain's existing operations.

22 Dec 2005

Plant stem cell breakthrough made

Totipotent stem cells allow plants to build new organs throughout their whole life. But it has been unclear how hormones and genetic factors work together to prevent plants from having growth that is either stunted, or uncontrolled and tumor-like. Scientists from the Max Planck Institute for Developmental Biology have now uncovered a feedback mechanism, involving a growth-enhancing hormone and a regulatory protein, which controls the number of stem cells the plant produces.

22 Dec 2005

Electrical microstimulation allows researchers to map the brain for the first time

Over the last two centuries electrical microstimulation has been often used to demonstrate causal links between neural activity and specific behaviors or cognitive functions. However, to understand the mechanisms by which electrical microstimulation can cause alternations in behaviors and cognitive functions it is imperative to characterize the cortical activity patterns that are elicited by stimulation locally around the electrode and in other functionally connected areas.

22 Dec 2005

Chromosome link found between alcohol addiction and smoking

Scientists have found in a study of tobacco users that their drinking behavior is linked to some of the same chromosome regions associated with alcohol addiction.

22 Dec 2005

Study finds light sensing cells develop before vision

Investigators at Washington University School of Medicine in St. Louis have found that cells making up a non-visual system in the eye are in place and functioning long before the rods and cones that process light into vision.

22 Dec 2005